Retrospective Analysis of Pregnancy Terminations: 9-Years Experience at a Tertiary Hospital in Southeastern Turkey
Objective: To determine the indications for termination of pregnancy, and their consistency with autopsy data to offer an insight into termination of pregnancy having regard to conditions in Turkey. Study Design: Three hundred and ninety-one pregnancies terminated before the 24th gestational week...
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Medical Network
2021-04-01
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| Series: | Gynecology Obstetrics & Reproductive Medicine |
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| Online Access: | https://gorm.com.tr/index.php/GORM/article/view/934 |
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| author | Neslihan Bayramoglu Tepe Reyhan Gunduz Omer Faruk Dizibuyuk Huseyin Caglayan Ozcan Ozge Komurcu Karuserci Seyhun Sucu Tanyeli Guneyligil Kazaz Ali Irfan Kutlar |
| author_facet | Neslihan Bayramoglu Tepe Reyhan Gunduz Omer Faruk Dizibuyuk Huseyin Caglayan Ozcan Ozge Komurcu Karuserci Seyhun Sucu Tanyeli Guneyligil Kazaz Ali Irfan Kutlar |
| author_sort | Neslihan Bayramoglu Tepe |
| collection | DOAJ |
| description |
Objective: To determine the indications for termination of pregnancy, and their consistency with autopsy data to offer an insight into termination of pregnancy having regard to conditions in Turkey.
Study Design: Three hundred and ninety-one pregnancies terminated before the 24th gestational week were enrolled in this study. Maternal age, gravidity, parity, abortion, the status of folic acid usage, consanguineous marital status, gestational week, anomalies that led to termination and pathological diagnoses were recorded. Anomalies that led to termination were grouped as central nervous system , cardiovascular system, gastrointestinal system, genitourinary system, pulmonary, musculoskeletal, head-neck, chromosomal, genetic, multiple anomalies and others. Four groups were formed based on the consistency of prenatal ultrasound diagnosis with pathological diagnosis.
Results: Mean age, gravidity, parity, abortion, and gestational week were 28 years, 3, 1, 1, and 15.7 weeks, respectively. One hundred and thirty-eight (35.2%) patients had consanguineous marriage. Three major causes of termination were central nervous system (45.78%), head-neck (17.4%) and multiple anomalies (14%). One hundred and twenty-eight (71.5%) patients with central nervous system anomalies were not using folic acid. Comparison of prenatal ultrasound findings with pathology results, 275 (70.3%) patients had full consistency, 46 (11.8%) had other findings at autopsy besides the confirmed sonographic findings, 34 (8.7%) had some sonographic findings not confirmed at autopsy, and 4 (1%) had no consistency between the findings.
Conclusion: Central nervous system anomalies constitute the most common indication for termination of pregnancy in this retrospective study. Low rate of periconceptional folic acid among those cases is remarkable. First-trimester screening for earlier detection of fetal anomalies may be important in high-risk groups such as those with consanguineous marriages.
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| format | Article |
| id | doaj-art-020d8429a6f8436ab88fe4e82026c569 |
| institution | Kabale University |
| issn | 1300-4751 2602-4918 |
| language | English |
| publishDate | 2021-04-01 |
| publisher | Medical Network |
| record_format | Article |
| series | Gynecology Obstetrics & Reproductive Medicine |
| spelling | doaj-art-020d8429a6f8436ab88fe4e82026c5692025-02-11T21:11:52ZengMedical NetworkGynecology Obstetrics & Reproductive Medicine1300-47512602-49182021-04-0127110.21613/GORM.2019.934Retrospective Analysis of Pregnancy Terminations: 9-Years Experience at a Tertiary Hospital in Southeastern TurkeyNeslihan Bayramoglu Tepe0Reyhan Gunduz1Omer Faruk Dizibuyuk2Huseyin Caglayan Ozcan3Ozge Komurcu Karuserci4Seyhun Sucu5Tanyeli Guneyligil Kazaz6Ali Irfan Kutlar7Gaziantep University School of Medicine Department of Obstetrics and GynecologyGaziantep Ersin ARslan Education and Research hospitalDepartment of Pathology, University of GaziantepDepartment of Obstetrics and Gynecology, University of GaziantepDepartment of Obstetrics and Gynecology, University of GaziantepDepartment of Obstetrics and Gynecology, University of GaziantepDepartment of Biostatistics, University of Gaziantep, GaziantepDepartment of Obstetrics and Gynecology, University of Gaziantep Objective: To determine the indications for termination of pregnancy, and their consistency with autopsy data to offer an insight into termination of pregnancy having regard to conditions in Turkey. Study Design: Three hundred and ninety-one pregnancies terminated before the 24th gestational week were enrolled in this study. Maternal age, gravidity, parity, abortion, the status of folic acid usage, consanguineous marital status, gestational week, anomalies that led to termination and pathological diagnoses were recorded. Anomalies that led to termination were grouped as central nervous system , cardiovascular system, gastrointestinal system, genitourinary system, pulmonary, musculoskeletal, head-neck, chromosomal, genetic, multiple anomalies and others. Four groups were formed based on the consistency of prenatal ultrasound diagnosis with pathological diagnosis. Results: Mean age, gravidity, parity, abortion, and gestational week were 28 years, 3, 1, 1, and 15.7 weeks, respectively. One hundred and thirty-eight (35.2%) patients had consanguineous marriage. Three major causes of termination were central nervous system (45.78%), head-neck (17.4%) and multiple anomalies (14%). One hundred and twenty-eight (71.5%) patients with central nervous system anomalies were not using folic acid. Comparison of prenatal ultrasound findings with pathology results, 275 (70.3%) patients had full consistency, 46 (11.8%) had other findings at autopsy besides the confirmed sonographic findings, 34 (8.7%) had some sonographic findings not confirmed at autopsy, and 4 (1%) had no consistency between the findings. Conclusion: Central nervous system anomalies constitute the most common indication for termination of pregnancy in this retrospective study. Low rate of periconceptional folic acid among those cases is remarkable. First-trimester screening for earlier detection of fetal anomalies may be important in high-risk groups such as those with consanguineous marriages. https://gorm.com.tr/index.php/GORM/article/view/934Fetal anomaliesPregnancyTermination |
| spellingShingle | Neslihan Bayramoglu Tepe Reyhan Gunduz Omer Faruk Dizibuyuk Huseyin Caglayan Ozcan Ozge Komurcu Karuserci Seyhun Sucu Tanyeli Guneyligil Kazaz Ali Irfan Kutlar Retrospective Analysis of Pregnancy Terminations: 9-Years Experience at a Tertiary Hospital in Southeastern Turkey Gynecology Obstetrics & Reproductive Medicine Fetal anomalies Pregnancy Termination |
| title | Retrospective Analysis of Pregnancy Terminations: 9-Years Experience at a Tertiary Hospital in Southeastern Turkey |
| title_full | Retrospective Analysis of Pregnancy Terminations: 9-Years Experience at a Tertiary Hospital in Southeastern Turkey |
| title_fullStr | Retrospective Analysis of Pregnancy Terminations: 9-Years Experience at a Tertiary Hospital in Southeastern Turkey |
| title_full_unstemmed | Retrospective Analysis of Pregnancy Terminations: 9-Years Experience at a Tertiary Hospital in Southeastern Turkey |
| title_short | Retrospective Analysis of Pregnancy Terminations: 9-Years Experience at a Tertiary Hospital in Southeastern Turkey |
| title_sort | retrospective analysis of pregnancy terminations 9 years experience at a tertiary hospital in southeastern turkey |
| topic | Fetal anomalies Pregnancy Termination |
| url | https://gorm.com.tr/index.php/GORM/article/view/934 |
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