Impact of Nutritional Factors on Colorectal Cancer: Implication the molecular mechanisms of Vitamins Supplementation
Colorectal cancer (CRC) is the leading cause of death from gastrointestinal cancer, the second largest cause of cancer-related death worldwide, and the third most common cancer in both men and women. Bad eating habits, smoking, intestinal inflammatory diseases, polyps, aging, and genetic factors al...
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| Language: | English |
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German Journal of Pharmaceuticals and Biomaterials
2025-01-01
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| Series: | German Journal of Pharmaceuticals and Biomaterials |
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| Online Access: | https://www.gjpb.de/index.php/gjpb/article/view/134 |
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| author | Hossna M. Ismail Abdel-Aziz S. Shatat |
| author_facet | Hossna M. Ismail Abdel-Aziz S. Shatat |
| author_sort | Hossna M. Ismail |
| collection | DOAJ |
| description |
Colorectal cancer (CRC) is the leading cause of death from gastrointestinal cancer, the second largest cause of cancer-related death worldwide, and the third most common cancer in both men and women. Bad eating habits, smoking, intestinal inflammatory diseases, polyps, aging, and genetic factors all increase the risk of developing colorectal cancer. More interestingly, vitamin deficiency has been associated with an increased risk of colorectal cancer. We reviewed the published significance of vitamin supplementation on colorectal cancer proliferation, survival, apoptosis, angiogenesis and migration, focusing on the possible molecular mechanisms of water-soluble and fat-soluble vitamins to provide protective suggestions to minimize the occurrence and progression of colorectal cancer.
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| format | Article |
| id | doaj-art-037cc19275074eeeaa7d6f7d3bdc09a0 |
| institution | Kabale University |
| issn | 2750-624X 2750-6258 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | German Journal of Pharmaceuticals and Biomaterials |
| record_format | Article |
| series | German Journal of Pharmaceuticals and Biomaterials |
| spelling | doaj-art-037cc19275074eeeaa7d6f7d3bdc09a02025-02-11T06:26:19ZengGerman Journal of Pharmaceuticals and BiomaterialsGerman Journal of Pharmaceuticals and Biomaterials2750-624X2750-62582025-01-013410.5530/gjpb.2024.4.12Impact of Nutritional Factors on Colorectal Cancer: Implication the molecular mechanisms of Vitamins SupplementationHossna M. Ismail 0Abdel-Aziz S. Shatat11)Ministry of Health & Population, Alsharqia, Egypt. 2) Professional Clinical Nutrition Master Program, Faculty of Pharmacy, Suez Canal University, Ismailia, Egypt.Department of Pharmacology and Toxicology, Faculty of Pharmacy, Al-Azhar University, Cairo, Egypt. Colorectal cancer (CRC) is the leading cause of death from gastrointestinal cancer, the second largest cause of cancer-related death worldwide, and the third most common cancer in both men and women. Bad eating habits, smoking, intestinal inflammatory diseases, polyps, aging, and genetic factors all increase the risk of developing colorectal cancer. More interestingly, vitamin deficiency has been associated with an increased risk of colorectal cancer. We reviewed the published significance of vitamin supplementation on colorectal cancer proliferation, survival, apoptosis, angiogenesis and migration, focusing on the possible molecular mechanisms of water-soluble and fat-soluble vitamins to provide protective suggestions to minimize the occurrence and progression of colorectal cancer. https://www.gjpb.de/index.php/gjpb/article/view/134colorectal cancernutritional factorsvitamins supplementation |
| spellingShingle | Hossna M. Ismail Abdel-Aziz S. Shatat Impact of Nutritional Factors on Colorectal Cancer: Implication the molecular mechanisms of Vitamins Supplementation German Journal of Pharmaceuticals and Biomaterials colorectal cancer nutritional factors vitamins supplementation |
| title | Impact of Nutritional Factors on Colorectal Cancer: Implication the molecular mechanisms of Vitamins Supplementation |
| title_full | Impact of Nutritional Factors on Colorectal Cancer: Implication the molecular mechanisms of Vitamins Supplementation |
| title_fullStr | Impact of Nutritional Factors on Colorectal Cancer: Implication the molecular mechanisms of Vitamins Supplementation |
| title_full_unstemmed | Impact of Nutritional Factors on Colorectal Cancer: Implication the molecular mechanisms of Vitamins Supplementation |
| title_short | Impact of Nutritional Factors on Colorectal Cancer: Implication the molecular mechanisms of Vitamins Supplementation |
| title_sort | impact of nutritional factors on colorectal cancer implication the molecular mechanisms of vitamins supplementation |
| topic | colorectal cancer nutritional factors vitamins supplementation |
| url | https://www.gjpb.de/index.php/gjpb/article/view/134 |
| work_keys_str_mv | AT hossnamismail impactofnutritionalfactorsoncolorectalcancerimplicationthemolecularmechanismsofvitaminssupplementation AT abdelazizsshatat impactofnutritionalfactorsoncolorectalcancerimplicationthemolecularmechanismsofvitaminssupplementation |