RETRACTED: Modern Subtype Classification and Outlier Detection Using the Attention Embedder to Transform Ovarian Cancer Diagnosis

Ovarian cancer, a deadly female reproductive system disease, is a significant challenge in medical research due to its notorious lethality. Addressing ovarian cancer in the current medical landscape has become more complex than ever. This research explores the complex field of Ovarian Cancer Subtype...

Full description

Saved in:
Bibliographic Details
Main Authors: S. M. Nuruzzaman Nobel, S M Masfequier Rahman Swapno, Md. Ashraful Hossain, Mejdl Safran, Sultan Alfarhood, Md. Mohsin Kabir, M. F. Mridha
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Tomography
Subjects:
Online Access:https://www.mdpi.com/2379-139X/10/1/10
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1825202037026979840
author S. M. Nuruzzaman Nobel
S M Masfequier Rahman Swapno
Md. Ashraful Hossain
Mejdl Safran
Sultan Alfarhood
Md. Mohsin Kabir
M. F. Mridha
author_facet S. M. Nuruzzaman Nobel
S M Masfequier Rahman Swapno
Md. Ashraful Hossain
Mejdl Safran
Sultan Alfarhood
Md. Mohsin Kabir
M. F. Mridha
author_sort S. M. Nuruzzaman Nobel
collection DOAJ
description Ovarian cancer, a deadly female reproductive system disease, is a significant challenge in medical research due to its notorious lethality. Addressing ovarian cancer in the current medical landscape has become more complex than ever. This research explores the complex field of Ovarian Cancer Subtype Classification and the crucial task of Outlier Detection, driven by a progressive automated system, as the need to fight this unforgiving illness becomes critical. This study primarily uses a unique dataset painstakingly selected from 20 esteemed medical institutes. The dataset includes a wide range of images, such as tissue microarray (TMA) images at 40× magnification and whole-slide images (WSI) at 20× magnification. The research is fully committed to identifying abnormalities within this complex environment, going beyond the classification of subtypes of ovarian cancer. We proposed a new Attention Embedder, a state-of-the-art model with effective results in ovarian cancer subtype classification and outlier detection. Using images magnified WSI, the model demonstrated an astonishing 96.42% training accuracy and 95.10% validation accuracy. Similarly, with images magnified via a TMA, the model performed well, obtaining a validation accuracy of 94.90% and a training accuracy of 93.45%. Our fine-tuned hyperparameter testing resulted in exceptional performance on independent images. At 20× magnification, we achieved an accuracy of 93.56%. Even at 40× magnification, our testing accuracy remained high, at 91.37%. This study highlights how machine learning can revolutionize the medical field’s ability to classify ovarian cancer subtypes and identify outliers, giving doctors a valuable tool to lessen the severe effects of the disease. Adopting this novel method is likely to improve the practice of medicine and give people living with ovarian cancer worldwide hope.
format Article
id doaj-art-038cd72f49ff4c618e14dde4693c5f9b
institution Kabale University
issn 2379-1381
2379-139X
language English
publishDate 2024-01-01
publisher MDPI AG
record_format Article
series Tomography
spelling doaj-art-038cd72f49ff4c618e14dde4693c5f9b2025-02-07T15:25:04ZengMDPI AGTomography2379-13812379-139X2024-01-0110110513210.3390/tomography10010010RETRACTED: Modern Subtype Classification and Outlier Detection Using the Attention Embedder to Transform Ovarian Cancer DiagnosisS. M. Nuruzzaman Nobel0S M Masfequier Rahman Swapno1Md. Ashraful Hossain2Mejdl Safran3Sultan Alfarhood4Md. Mohsin Kabir5M. F. Mridha6Department of Computer Science and Engineering, Bangladesh University of Business and Technology, Dhaka 1216, BangladeshDepartment of Computer Science and Engineering, Bangladesh University of Business and Technology, Dhaka 1216, BangladeshDepartment of Computer Science and Engineering, Bangladesh University of Business and Technology, Dhaka 1216, BangladeshDepartment of Computer Science, College of Computer and Information Sciences, King Saud University, P.O. Box 51178, Riyadh 11543, Saudi ArabiaDepartment of Computer Science, College of Computer and Information Sciences, King Saud University, P.O. Box 51178, Riyadh 11543, Saudi ArabiaSuperior Polytechnic School, University of Girona, 17071 Girona, SpainDepartment of Computer Science, American International University-Bangladesh, Dhaka 1229, BangladeshOvarian cancer, a deadly female reproductive system disease, is a significant challenge in medical research due to its notorious lethality. Addressing ovarian cancer in the current medical landscape has become more complex than ever. This research explores the complex field of Ovarian Cancer Subtype Classification and the crucial task of Outlier Detection, driven by a progressive automated system, as the need to fight this unforgiving illness becomes critical. This study primarily uses a unique dataset painstakingly selected from 20 esteemed medical institutes. The dataset includes a wide range of images, such as tissue microarray (TMA) images at 40× magnification and whole-slide images (WSI) at 20× magnification. The research is fully committed to identifying abnormalities within this complex environment, going beyond the classification of subtypes of ovarian cancer. We proposed a new Attention Embedder, a state-of-the-art model with effective results in ovarian cancer subtype classification and outlier detection. Using images magnified WSI, the model demonstrated an astonishing 96.42% training accuracy and 95.10% validation accuracy. Similarly, with images magnified via a TMA, the model performed well, obtaining a validation accuracy of 94.90% and a training accuracy of 93.45%. Our fine-tuned hyperparameter testing resulted in exceptional performance on independent images. At 20× magnification, we achieved an accuracy of 93.56%. Even at 40× magnification, our testing accuracy remained high, at 91.37%. This study highlights how machine learning can revolutionize the medical field’s ability to classify ovarian cancer subtypes and identify outliers, giving doctors a valuable tool to lessen the severe effects of the disease. Adopting this novel method is likely to improve the practice of medicine and give people living with ovarian cancer worldwide hope.https://www.mdpi.com/2379-139X/10/1/10ovarian cancerattention embeddertransfer learningcancer subtypecomputer visionoutlier detection
spellingShingle S. M. Nuruzzaman Nobel
S M Masfequier Rahman Swapno
Md. Ashraful Hossain
Mejdl Safran
Sultan Alfarhood
Md. Mohsin Kabir
M. F. Mridha
RETRACTED: Modern Subtype Classification and Outlier Detection Using the Attention Embedder to Transform Ovarian Cancer Diagnosis
Tomography
ovarian cancer
attention embedder
transfer learning
cancer subtype
computer vision
outlier detection
title RETRACTED: Modern Subtype Classification and Outlier Detection Using the Attention Embedder to Transform Ovarian Cancer Diagnosis
title_full RETRACTED: Modern Subtype Classification and Outlier Detection Using the Attention Embedder to Transform Ovarian Cancer Diagnosis
title_fullStr RETRACTED: Modern Subtype Classification and Outlier Detection Using the Attention Embedder to Transform Ovarian Cancer Diagnosis
title_full_unstemmed RETRACTED: Modern Subtype Classification and Outlier Detection Using the Attention Embedder to Transform Ovarian Cancer Diagnosis
title_short RETRACTED: Modern Subtype Classification and Outlier Detection Using the Attention Embedder to Transform Ovarian Cancer Diagnosis
title_sort retracted modern subtype classification and outlier detection using the attention embedder to transform ovarian cancer diagnosis
topic ovarian cancer
attention embedder
transfer learning
cancer subtype
computer vision
outlier detection
url https://www.mdpi.com/2379-139X/10/1/10
work_keys_str_mv AT smnuruzzamannobel retractedmodernsubtypeclassificationandoutlierdetectionusingtheattentionembeddertotransformovariancancerdiagnosis
AT smmasfequierrahmanswapno retractedmodernsubtypeclassificationandoutlierdetectionusingtheattentionembeddertotransformovariancancerdiagnosis
AT mdashrafulhossain retractedmodernsubtypeclassificationandoutlierdetectionusingtheattentionembeddertotransformovariancancerdiagnosis
AT mejdlsafran retractedmodernsubtypeclassificationandoutlierdetectionusingtheattentionembeddertotransformovariancancerdiagnosis
AT sultanalfarhood retractedmodernsubtypeclassificationandoutlierdetectionusingtheattentionembeddertotransformovariancancerdiagnosis
AT mdmohsinkabir retractedmodernsubtypeclassificationandoutlierdetectionusingtheattentionembeddertotransformovariancancerdiagnosis
AT mfmridha retractedmodernsubtypeclassificationandoutlierdetectionusingtheattentionembeddertotransformovariancancerdiagnosis