Genetic Polymorphism in Peripartum Cardiomyopathy
Peripartum cardiomyopathy (PPCM) is a rare type of cardiomyopathy. PPCM is a potentially life-threatening pregnancy-associated disease that typically arises in peripartum period and is marked with left ventricular (LV) dysfunction and heart failure. The cause of PPCM remain unclear, but several mec...
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Medical Network
2021-12-01
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| Series: | Gynecology Obstetrics & Reproductive Medicine |
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| Online Access: | https://gorm.com.tr/index.php/GORM/article/view/1072 |
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| _version_ | 1823857324645679104 |
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| author | Ivana Purnama Dewi Johanes Nugroho |
| author_facet | Ivana Purnama Dewi Johanes Nugroho |
| author_sort | Ivana Purnama Dewi |
| collection | DOAJ |
| description |
Peripartum cardiomyopathy (PPCM) is a rare type of cardiomyopathy. PPCM is a potentially life-threatening pregnancy-associated disease that typically arises in peripartum period and is marked with left ventricular (LV) dysfunction and heart failure. The cause of PPCM remain unclear, but several mechanisms have been proposed ehich indices a potentially multi-factorial etiology. Early case reports identified overlap between familial dilated cardiomyopathy (DCM) and PPCM, although the degree of overlap is largely unknown. Many evidence supporting a contribution from gene mutations in PPCM includes genome-wide association studies, familial occurrence, variable prevalence among different regions and ethnicities, and more recent investigations of panels of genes for mutations among women with PPCM. Although the true incidence of genetic cardiomyopathy is not yet known among women with PPCM, there is substantial evidence demonstrating that genetic contribution to their condition.
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| format | Article |
| id | doaj-art-0612d06a07794140ae5fb7326e168967 |
| institution | Kabale University |
| issn | 1300-4751 2602-4918 |
| language | English |
| publishDate | 2021-12-01 |
| publisher | Medical Network |
| record_format | Article |
| series | Gynecology Obstetrics & Reproductive Medicine |
| spelling | doaj-art-0612d06a07794140ae5fb7326e1689672025-02-11T21:13:48ZengMedical NetworkGynecology Obstetrics & Reproductive Medicine1300-47512602-49182021-12-0127310.21613/GORM.2021.1072Genetic Polymorphism in Peripartum CardiomyopathyIvana Purnama Dewi0Johanes Nugroho1Duta Wacana Christian UniversityAirlangga University Peripartum cardiomyopathy (PPCM) is a rare type of cardiomyopathy. PPCM is a potentially life-threatening pregnancy-associated disease that typically arises in peripartum period and is marked with left ventricular (LV) dysfunction and heart failure. The cause of PPCM remain unclear, but several mechanisms have been proposed ehich indices a potentially multi-factorial etiology. Early case reports identified overlap between familial dilated cardiomyopathy (DCM) and PPCM, although the degree of overlap is largely unknown. Many evidence supporting a contribution from gene mutations in PPCM includes genome-wide association studies, familial occurrence, variable prevalence among different regions and ethnicities, and more recent investigations of panels of genes for mutations among women with PPCM. Although the true incidence of genetic cardiomyopathy is not yet known among women with PPCM, there is substantial evidence demonstrating that genetic contribution to their condition. https://gorm.com.tr/index.php/GORM/article/view/1072peripartum cardiomyopathygeneticpregnancyfamilial dilated cardiomyopathy |
| spellingShingle | Ivana Purnama Dewi Johanes Nugroho Genetic Polymorphism in Peripartum Cardiomyopathy Gynecology Obstetrics & Reproductive Medicine peripartum cardiomyopathy genetic pregnancy familial dilated cardiomyopathy |
| title | Genetic Polymorphism in Peripartum Cardiomyopathy |
| title_full | Genetic Polymorphism in Peripartum Cardiomyopathy |
| title_fullStr | Genetic Polymorphism in Peripartum Cardiomyopathy |
| title_full_unstemmed | Genetic Polymorphism in Peripartum Cardiomyopathy |
| title_short | Genetic Polymorphism in Peripartum Cardiomyopathy |
| title_sort | genetic polymorphism in peripartum cardiomyopathy |
| topic | peripartum cardiomyopathy genetic pregnancy familial dilated cardiomyopathy |
| url | https://gorm.com.tr/index.php/GORM/article/view/1072 |
| work_keys_str_mv | AT ivanapurnamadewi geneticpolymorphisminperipartumcardiomyopathy AT johanesnugroho geneticpolymorphisminperipartumcardiomyopathy |