Neurological Crisis Following Intravenous Ozone Therapy; a Case Report

Ozone therapy, often marketed as an immune-boosting alternative treatment, lacks robust evidence of efficacy and poses significant safety risks. Despite claims of therapeutic benefits, Regulatory agencies, such as the U.S. Food and Drug Administration (FDA), warn against its use due to its toxic pr...

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Main Authors: Chloe Y Y Wong, Komal Saxena, John Meneer, Koshy George, Gerben Keijzers
Format: Article
Language:English
Published: Shahid Beheshti University of Medical Sciences 2025-01-01
Series:Archives of Academic Emergency Medicine
Subjects:
Online Access:https://journals.sbmu.ac.ir/aaem/index.php/AAEM/article/view/2592
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author Chloe Y Y Wong
Komal Saxena
John Meneer
Koshy George
Gerben Keijzers
author_facet Chloe Y Y Wong
Komal Saxena
John Meneer
Koshy George
Gerben Keijzers
author_sort Chloe Y Y Wong
collection DOAJ
description Ozone therapy, often marketed as an immune-boosting alternative treatment, lacks robust evidence of efficacy and poses significant safety risks. Despite claims of therapeutic benefits, Regulatory agencies, such as the U.S. Food and Drug Administration (FDA), warn against its use due to its toxic properties and lack of proven benefits at tolerable exposure levels. This case report highlights severe neurological complications, including ischemic infarcts and persistent cognitive deficits, following intravenous ozone (O3) therapy in a previously healthy patient. A 36-year-old woman presented to the emergency department with chest pain, syncope, and generalized seizure shortly after receiving intravenous ozone therapy. Diagnostic imaging revealed multiple ischemic infarcts in the thalamus and cerebellum, consistent with an embolic event. The patient required intensive care unit (ICU) admission, and despite improved neurological function experienced lasting cognitive impairments necessitating long-term rehabilitation.
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institution Kabale University
issn 2645-4904
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publishDate 2025-01-01
publisher Shahid Beheshti University of Medical Sciences
record_format Article
series Archives of Academic Emergency Medicine
spelling doaj-art-0660b8ed9be14bb88bb03864180d26d92025-02-11T20:47:50ZengShahid Beheshti University of Medical SciencesArchives of Academic Emergency Medicine2645-49042025-01-0113110.22037/aaemj.v13i1.2592Neurological Crisis Following Intravenous Ozone Therapy; a Case ReportChloe Y Y Wong0Komal SaxenaJohn Meneer Koshy GeorgeGerben KeijzersGold Coast Health and Hospital Services, Australasian College of Emergency Medicine Ozone therapy, often marketed as an immune-boosting alternative treatment, lacks robust evidence of efficacy and poses significant safety risks. Despite claims of therapeutic benefits, Regulatory agencies, such as the U.S. Food and Drug Administration (FDA), warn against its use due to its toxic properties and lack of proven benefits at tolerable exposure levels. This case report highlights severe neurological complications, including ischemic infarcts and persistent cognitive deficits, following intravenous ozone (O3) therapy in a previously healthy patient. A 36-year-old woman presented to the emergency department with chest pain, syncope, and generalized seizure shortly after receiving intravenous ozone therapy. Diagnostic imaging revealed multiple ischemic infarcts in the thalamus and cerebellum, consistent with an embolic event. The patient required intensive care unit (ICU) admission, and despite improved neurological function experienced lasting cognitive impairments necessitating long-term rehabilitation. https://journals.sbmu.ac.ir/aaem/index.php/AAEM/article/view/2592Embolism, AirComplementary TherapiesEmergency ServiceHospitalNeurologyOzone
spellingShingle Chloe Y Y Wong
Komal Saxena
John Meneer
Koshy George
Gerben Keijzers
Neurological Crisis Following Intravenous Ozone Therapy; a Case Report
Archives of Academic Emergency Medicine
Embolism, Air
Complementary Therapies
Emergency Service
Hospital
Neurology
Ozone
title Neurological Crisis Following Intravenous Ozone Therapy; a Case Report
title_full Neurological Crisis Following Intravenous Ozone Therapy; a Case Report
title_fullStr Neurological Crisis Following Intravenous Ozone Therapy; a Case Report
title_full_unstemmed Neurological Crisis Following Intravenous Ozone Therapy; a Case Report
title_short Neurological Crisis Following Intravenous Ozone Therapy; a Case Report
title_sort neurological crisis following intravenous ozone therapy a case report
topic Embolism, Air
Complementary Therapies
Emergency Service
Hospital
Neurology
Ozone
url https://journals.sbmu.ac.ir/aaem/index.php/AAEM/article/view/2592
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AT komalsaxena neurologicalcrisisfollowingintravenousozonetherapyacasereport
AT johnmeneer neurologicalcrisisfollowingintravenousozonetherapyacasereport
AT koshygeorge neurologicalcrisisfollowingintravenousozonetherapyacasereport
AT gerbenkeijzers neurologicalcrisisfollowingintravenousozonetherapyacasereport