Pulmonary arteriovenous malformation causing lung sequestration and media infarction: a case report

Pulmonary arteriovenous malformations (PAVMs) are rare vascular malformations of the lungs. Direct communication of pulmonary arteries to pulmonary veins is the defining characteristic allowing venous blood to bypass the pulmonary capillary system and avoiding an efficient oxygenation process. The c...

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Main Authors: Raffaella Griffo, Laura V. Klotz, Lena Brendel, Romina Rösch, Benedikt Niedermaier, Kai Schlamp, Mark Kriegsmann, Martin M. Eichhorn, Hauke Winter
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Medicine
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Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2025.1490820/full
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author Raffaella Griffo
Laura V. Klotz
Laura V. Klotz
Lena Brendel
Romina Rösch
Benedikt Niedermaier
Kai Schlamp
Mark Kriegsmann
Mark Kriegsmann
Martin M. Eichhorn
Martin M. Eichhorn
Hauke Winter
Hauke Winter
author_facet Raffaella Griffo
Laura V. Klotz
Laura V. Klotz
Lena Brendel
Romina Rösch
Benedikt Niedermaier
Kai Schlamp
Mark Kriegsmann
Mark Kriegsmann
Martin M. Eichhorn
Martin M. Eichhorn
Hauke Winter
Hauke Winter
author_sort Raffaella Griffo
collection DOAJ
description Pulmonary arteriovenous malformations (PAVMs) are rare vascular malformations of the lungs. Direct communication of pulmonary arteries to pulmonary veins is the defining characteristic allowing venous blood to bypass the pulmonary capillary system and avoiding an efficient oxygenation process. The complexity of the pathology lies not only in the variety of its manifestations, but also in the choice of the most appropriate and effective treatment. We present a case of a complex PAVM associated with a persistent foramen ovale, with stroke as the onset symptom. Despite timely multidisciplinary treatment of the malformation, a potentially fatal pulmonary complication occurred, highlighting the critical importance of early, interdisciplinary management and ongoing follow-up of PAVMs, particularly in preventing life-threatening outcomes.
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institution Kabale University
issn 2296-858X
language English
publishDate 2025-02-01
publisher Frontiers Media S.A.
record_format Article
series Frontiers in Medicine
spelling doaj-art-0e14fda442d94a99b24e0c27413d239b2025-02-11T05:10:15ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2025-02-011210.3389/fmed.2025.14908201490820Pulmonary arteriovenous malformation causing lung sequestration and media infarction: a case reportRaffaella Griffo0Laura V. Klotz1Laura V. Klotz2Lena Brendel3Romina Rösch4Benedikt Niedermaier5Kai Schlamp6Mark Kriegsmann7Mark Kriegsmann8Martin M. Eichhorn9Martin M. Eichhorn10Hauke Winter11Hauke Winter12Thoraxklinik, Department of Thoracic Surgery, Heidelberg University Hospital, Heidelberg, GermanyThoraxklinik, Department of Thoracic Surgery, Heidelberg University Hospital, Heidelberg, GermanyTranslational Lung Research Center (TLRC), Heidelberg, GermanyThoraxklinik, Department of Thoracic Surgery, Heidelberg University Hospital, Heidelberg, GermanyThoraxklinik, Department of Thoracic Surgery, Heidelberg University Hospital, Heidelberg, GermanyThoraxklinik, Department of Thoracic Surgery, Heidelberg University Hospital, Heidelberg, GermanyThoraxklinik, Department of Radiology, Heidelberg University Hospital, Heidelberg, GermanyTranslational Lung Research Center (TLRC), Heidelberg, GermanyThoraxklinik, Department of Pathology, Heidelberg University Hospital, Heidelberg, GermanyThoraxklinik, Department of Thoracic Surgery, Heidelberg University Hospital, Heidelberg, GermanyTranslational Lung Research Center (TLRC), Heidelberg, GermanyThoraxklinik, Department of Thoracic Surgery, Heidelberg University Hospital, Heidelberg, GermanyTranslational Lung Research Center (TLRC), Heidelberg, GermanyPulmonary arteriovenous malformations (PAVMs) are rare vascular malformations of the lungs. Direct communication of pulmonary arteries to pulmonary veins is the defining characteristic allowing venous blood to bypass the pulmonary capillary system and avoiding an efficient oxygenation process. The complexity of the pathology lies not only in the variety of its manifestations, but also in the choice of the most appropriate and effective treatment. We present a case of a complex PAVM associated with a persistent foramen ovale, with stroke as the onset symptom. Despite timely multidisciplinary treatment of the malformation, a potentially fatal pulmonary complication occurred, highlighting the critical importance of early, interdisciplinary management and ongoing follow-up of PAVMs, particularly in preventing life-threatening outcomes.https://www.frontiersin.org/articles/10.3389/fmed.2025.1490820/fulllung malformationthoracic surgerypulmonary arteriovenous malformationhereditary hemorrhagic telangiectasialung diseasecase report
spellingShingle Raffaella Griffo
Laura V. Klotz
Laura V. Klotz
Lena Brendel
Romina Rösch
Benedikt Niedermaier
Kai Schlamp
Mark Kriegsmann
Mark Kriegsmann
Martin M. Eichhorn
Martin M. Eichhorn
Hauke Winter
Hauke Winter
Pulmonary arteriovenous malformation causing lung sequestration and media infarction: a case report
Frontiers in Medicine
lung malformation
thoracic surgery
pulmonary arteriovenous malformation
hereditary hemorrhagic telangiectasia
lung disease
case report
title Pulmonary arteriovenous malformation causing lung sequestration and media infarction: a case report
title_full Pulmonary arteriovenous malformation causing lung sequestration and media infarction: a case report
title_fullStr Pulmonary arteriovenous malformation causing lung sequestration and media infarction: a case report
title_full_unstemmed Pulmonary arteriovenous malformation causing lung sequestration and media infarction: a case report
title_short Pulmonary arteriovenous malformation causing lung sequestration and media infarction: a case report
title_sort pulmonary arteriovenous malformation causing lung sequestration and media infarction a case report
topic lung malformation
thoracic surgery
pulmonary arteriovenous malformation
hereditary hemorrhagic telangiectasia
lung disease
case report
url https://www.frontiersin.org/articles/10.3389/fmed.2025.1490820/full
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