Application of deep learning models on single-cell RNA sequencing analysis uncovers novel markers of double negative T cells
Abstract Double negative T (DNT) cells are a unique subset of CD3 + TCRαβ + T lymphocytes that lack CD4, CD8, or NK1.1 expression and constitute 3–5% of the total T cell population in C57BL/6 mice. They have increasingly gained recognition for their novel roles in the immune system, especially under...
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Main Authors: | Tian Xu, Qin Xu, Ran Lu, David N. Oakland, Song Li, Liwu Li, Christopher M. Reilly, Xin M. Luo |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2024-12-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-024-82406-7 |
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