The changing landscape of antimicrobial resistance and use in South Africa: The need for access to new antibiotics: A position paper
Antibiotic resistance is a global threat, with a disproportionate burden of mortality in low- and middle-income countries. It is increasing in both the public and private healthcare sectors within South Africa, especially in Gram-negative organisms, and is associated with increased use of World...
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| Format: | Article |
| Language: | English |
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South African Medical Association
2024-10-01
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| Series: | South African Medical Journal |
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| Online Access: | https://samajournals.co.za/index.php/samj/article/view/2348 |
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| author | H Finlayson V Chibabhai P Jeena S Kolman W Lowman T C Manzini T Nana J Nuttall A Parker P Skosana V Ueckermann A Wise |
| author_facet | H Finlayson V Chibabhai P Jeena S Kolman W Lowman T C Manzini T Nana J Nuttall A Parker P Skosana V Ueckermann A Wise |
| author_sort | H Finlayson |
| collection | DOAJ |
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Antibiotic resistance is a global threat, with a disproportionate burden of mortality in low- and middle-income countries. It is increasing in both the public and private healthcare sectors within South Africa, especially in Gram-negative organisms, and is associated with increased use of World Health Organization watch and reserve antibiotics. There is a need for improved access to new antibiotics to treat infections caused by drug-resistant organisms in order to limit side-effects and improve patient outcomes of currently available antibiotics. We propose the responsible introduction of these new antibiotics with both administrative and clinical oversight in order to preserve the longevity of these precious antibiotics.
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| format | Article |
| id | doaj-art-125e7bbadc4b4c1ea0f8885190a5eaad |
| institution | Kabale University |
| issn | 0256-9574 2078-5135 |
| language | English |
| publishDate | 2024-10-01 |
| publisher | South African Medical Association |
| record_format | Article |
| series | South African Medical Journal |
| spelling | doaj-art-125e7bbadc4b4c1ea0f8885190a5eaad2025-02-10T12:25:37ZengSouth African Medical AssociationSouth African Medical Journal0256-95742078-51352024-10-011141010.7196/SAMJ.2024.v114i10.2348The changing landscape of antimicrobial resistance and use in South Africa: The need for access to new antibiotics: A position paperH Finlayson0V Chibabhai1P Jeena2S Kolman3W Lowman4T C Manzini5T Nana6J Nuttall7A Parker8P Skosana9V Ueckermann10A Wise11Department of Paediatrics and Child Health, Faculty of Health Sciences, Stellenbosch University, Cape Town, South AfricaDivision of Clinical Microbiology and Infectious Diseases, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South AfricaDepartment of Paediatrics and Child Health, College of Health Sciences, University of KwaZulu-Natal, Durban, South AfricaNelson Mandela Children’s Hospital, Johannesburg, South AfricaPathCare/Vermaak Pathologists, Gauteng; Wits Donald Gordon Medical Centre, University of the Witwatersrand, Johannesburg, South AfricaInfectious Disease Unit, Sefako Makgatho Health Science University and Dr George Mukhari Academic Hospital, Pretoria, South AfricaDivision of Clinical Microbiology and Infectious Diseases, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South AfricaPaediatric Infectious Diseases Unit, Department of Paediatrics and Child Health, Red Cross War Memorial Children’s Hospital, University of Cape Town, Cape Town, South AfricaUnit for Infection Prevention Control and Division of Infectious Diseases, Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South AfricaDepartment of Clinical Pharmacy, School of Pharmacy, Sefako Makgatho Health Sciences University, Pretoria, South AfricaDivision of Infectious Diseases, Department of Internal Medicine, Faculty of Health Sciences, University of Pretoria, South AfricaRahima Moosa Mother and Child Hospital, Department of Obstetrics and Gynaecology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa Antibiotic resistance is a global threat, with a disproportionate burden of mortality in low- and middle-income countries. It is increasing in both the public and private healthcare sectors within South Africa, especially in Gram-negative organisms, and is associated with increased use of World Health Organization watch and reserve antibiotics. There is a need for improved access to new antibiotics to treat infections caused by drug-resistant organisms in order to limit side-effects and improve patient outcomes of currently available antibiotics. We propose the responsible introduction of these new antibiotics with both administrative and clinical oversight in order to preserve the longevity of these precious antibiotics. https://samajournals.co.za/index.php/samj/article/view/2348antimicrobial resistanceantimicrobial useantibiotic stewardshipAwaRE antibiotics |
| spellingShingle | H Finlayson V Chibabhai P Jeena S Kolman W Lowman T C Manzini T Nana J Nuttall A Parker P Skosana V Ueckermann A Wise The changing landscape of antimicrobial resistance and use in South Africa: The need for access to new antibiotics: A position paper South African Medical Journal antimicrobial resistance antimicrobial use antibiotic stewardship AwaRE antibiotics |
| title | The changing landscape of antimicrobial resistance and use in South Africa: The need for access to new antibiotics: A position paper |
| title_full | The changing landscape of antimicrobial resistance and use in South Africa: The need for access to new antibiotics: A position paper |
| title_fullStr | The changing landscape of antimicrobial resistance and use in South Africa: The need for access to new antibiotics: A position paper |
| title_full_unstemmed | The changing landscape of antimicrobial resistance and use in South Africa: The need for access to new antibiotics: A position paper |
| title_short | The changing landscape of antimicrobial resistance and use in South Africa: The need for access to new antibiotics: A position paper |
| title_sort | changing landscape of antimicrobial resistance and use in south africa the need for access to new antibiotics a position paper |
| topic | antimicrobial resistance antimicrobial use antibiotic stewardship AwaRE antibiotics |
| url | https://samajournals.co.za/index.php/samj/article/view/2348 |
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