Biological activities of extracts of some plants which utilized in colds

Aim: In this study, antioxidant activities and antibacterial activities of acetone and chloroform extracts obtained from Rosa canina, Echinacea purpurea, Althaea officinalis and Glycyrrhiza glabra were explored. Methods: Disc diffusion method and minimum inhibition concentration (MIC) assays were us...

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Main Author: Sinem Aydin
Format: Article
Language:English
Published: Open Exploration 2024-08-01
Series:Exploration of Drug Science
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Online Access:https://www.explorationpub.com/uploads/Article/A100857/100857.pdf
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author Sinem Aydin
author_facet Sinem Aydin
author_sort Sinem Aydin
collection DOAJ
description Aim: In this study, antioxidant activities and antibacterial activities of acetone and chloroform extracts obtained from Rosa canina, Echinacea purpurea, Althaea officinalis and Glycyrrhiza glabra were explored. Methods: Disc diffusion method and minimum inhibition concentration (MIC) assays were used to reveal antibacterial activity of the extracts. Total phenolic content, total flavonoid content, total antioxidant capacity, DPPH and ABTS radical scavenging activity tests were performed to determine antioxidant activity of the extracts. Results: Acetone extracts of the studied plants showed higher activity than chloroform extracts. Both acetone and chloroform extracts of G. glabra produced higher inhibition zones compared to other plant extracts. The highest total phenol content was found in acetone extract of G. glabra while the lowest total phenol content was found in chloroform extract of R. canina. The highest and lowest total antioxidant capacity was determined as 247.28 ± 0.0557 µg ascorbic acid equivalent (AAE)/mL and 50.91 ± 0.0294 µg AAE/mL in chloroform extract of A. officinalis and acetone extract of A. officinalis, respectively. Conclusions: In the light of the obtained data, it was concluded that R. canina, E. purpurea, A. officinalis and G. glabra can be used as alternative natural antibacterial and antioxidant sources to synthetic antibacterial and antioxidant agents.
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spelling doaj-art-1388a140b85049b6b2c524ac5a713dce2025-02-08T03:30:12ZengOpen ExplorationExploration of Drug Science2836-76772024-08-012547348310.37349/eds.2024.00057Biological activities of extracts of some plants which utilized in coldsSinem Aydin0https://orcid.org/0000-0002-0484-7191Department of Biology, Giresun University, Giresun 28100, TurkeyAim: In this study, antioxidant activities and antibacterial activities of acetone and chloroform extracts obtained from Rosa canina, Echinacea purpurea, Althaea officinalis and Glycyrrhiza glabra were explored. Methods: Disc diffusion method and minimum inhibition concentration (MIC) assays were used to reveal antibacterial activity of the extracts. Total phenolic content, total flavonoid content, total antioxidant capacity, DPPH and ABTS radical scavenging activity tests were performed to determine antioxidant activity of the extracts. Results: Acetone extracts of the studied plants showed higher activity than chloroform extracts. Both acetone and chloroform extracts of G. glabra produced higher inhibition zones compared to other plant extracts. The highest total phenol content was found in acetone extract of G. glabra while the lowest total phenol content was found in chloroform extract of R. canina. The highest and lowest total antioxidant capacity was determined as 247.28 ± 0.0557 µg ascorbic acid equivalent (AAE)/mL and 50.91 ± 0.0294 µg AAE/mL in chloroform extract of A. officinalis and acetone extract of A. officinalis, respectively. Conclusions: In the light of the obtained data, it was concluded that R. canina, E. purpurea, A. officinalis and G. glabra can be used as alternative natural antibacterial and antioxidant sources to synthetic antibacterial and antioxidant agents.https://www.explorationpub.com/uploads/Article/A100857/100857.pdfplantantibioticreactive oxygen speciesantioxidantphenolic compound
spellingShingle Sinem Aydin
Biological activities of extracts of some plants which utilized in colds
Exploration of Drug Science
plant
antibiotic
reactive oxygen species
antioxidant
phenolic compound
title Biological activities of extracts of some plants which utilized in colds
title_full Biological activities of extracts of some plants which utilized in colds
title_fullStr Biological activities of extracts of some plants which utilized in colds
title_full_unstemmed Biological activities of extracts of some plants which utilized in colds
title_short Biological activities of extracts of some plants which utilized in colds
title_sort biological activities of extracts of some plants which utilized in colds
topic plant
antibiotic
reactive oxygen species
antioxidant
phenolic compound
url https://www.explorationpub.com/uploads/Article/A100857/100857.pdf
work_keys_str_mv AT sinemaydin biologicalactivitiesofextractsofsomeplantswhichutilizedincolds