Effect of platelet-rich fibrin on wound healing, adhesions, and hemostasis after inferior turbinoplasty surgery

Abstract Background Inferior turbinate enlargement is a prevalent cause of chronic nasal obstruction, often requiring surgical intervention when medical treatment fails. Platelet-rich fibrin (PRF) has been reported to mitigate post-operative complications following nasal surgeries. This work aims to...

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Main Authors: Abdelhakim Fouad Ghallab, Mohamed Fahmy Shendy, Samer Badie Kamel, Mohamed Ali Adam, Mohamed Goda Elnems
Format: Article
Language:English
Published: SpringerOpen 2025-02-01
Series:The Egyptian Journal of Otolaryngology
Subjects:
Online Access:https://doi.org/10.1186/s43163-025-00764-z
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author Abdelhakim Fouad Ghallab
Mohamed Fahmy Shendy
Samer Badie Kamel
Mohamed Ali Adam
Mohamed Goda Elnems
author_facet Abdelhakim Fouad Ghallab
Mohamed Fahmy Shendy
Samer Badie Kamel
Mohamed Ali Adam
Mohamed Goda Elnems
author_sort Abdelhakim Fouad Ghallab
collection DOAJ
description Abstract Background Inferior turbinate enlargement is a prevalent cause of chronic nasal obstruction, often requiring surgical intervention when medical treatment fails. Platelet-rich fibrin (PRF) has been reported to mitigate post-operative complications following nasal surgeries. This work aims to evaluate the efficacy of PRF on hemostasis, adhesions, crust formation, and mucosal healing post-turbinoplasty. Results Demographic characters showed no statistical differences in age (p = 0.62) or gender (p = 0.342), but the mean operative time was significantly shorter in the non-PRF group (22.80 ± 2.02) compared to the PRF group (p > 0.001). Early hemostasis and prevention of crustation were significantly better in the PRF group (p = 0.03 and p = 0.024, respectively). No significant difference was observed regarding adhesions between the groups (p = 1). Conclusion The PRF membrane is an affordable and easy method that acts as a protective layer, reducing crusting, ensuring hemostasis, promoting healing by shortening the period of recovery post inferior turbinoplasty and so improving the quality of life of the patients.
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institution Kabale University
issn 2090-8539
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publishDate 2025-02-01
publisher SpringerOpen
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series The Egyptian Journal of Otolaryngology
spelling doaj-art-166e2c01582d4946a266e457f0c76d222025-02-09T12:08:59ZengSpringerOpenThe Egyptian Journal of Otolaryngology2090-85392025-02-014111810.1186/s43163-025-00764-zEffect of platelet-rich fibrin on wound healing, adhesions, and hemostasis after inferior turbinoplasty surgeryAbdelhakim Fouad Ghallab0Mohamed Fahmy Shendy1Samer Badie Kamel2Mohamed Ali Adam3Mohamed Goda Elnems4Otolaryngology Department, Faculty of Medicine, Benha UniversityOtolaryngology Department, Faculty of Medicine, Benha UniversityOtolaryngology Department, Faculty of Medicine, Benha UniversityOtolaryngology Department, Faculty of Medicine, Benha UniversityOtolaryngology Department, Faculty of Medicine, Benha UniversityAbstract Background Inferior turbinate enlargement is a prevalent cause of chronic nasal obstruction, often requiring surgical intervention when medical treatment fails. Platelet-rich fibrin (PRF) has been reported to mitigate post-operative complications following nasal surgeries. This work aims to evaluate the efficacy of PRF on hemostasis, adhesions, crust formation, and mucosal healing post-turbinoplasty. Results Demographic characters showed no statistical differences in age (p = 0.62) or gender (p = 0.342), but the mean operative time was significantly shorter in the non-PRF group (22.80 ± 2.02) compared to the PRF group (p > 0.001). Early hemostasis and prevention of crustation were significantly better in the PRF group (p = 0.03 and p = 0.024, respectively). No significant difference was observed regarding adhesions between the groups (p = 1). Conclusion The PRF membrane is an affordable and easy method that acts as a protective layer, reducing crusting, ensuring hemostasis, promoting healing by shortening the period of recovery post inferior turbinoplasty and so improving the quality of life of the patients.https://doi.org/10.1186/s43163-025-00764-zHypertrophied inferior turbinatePlatelet-rich fibrinTurbinoplastyCrustationHemostasisHealing
spellingShingle Abdelhakim Fouad Ghallab
Mohamed Fahmy Shendy
Samer Badie Kamel
Mohamed Ali Adam
Mohamed Goda Elnems
Effect of platelet-rich fibrin on wound healing, adhesions, and hemostasis after inferior turbinoplasty surgery
The Egyptian Journal of Otolaryngology
Hypertrophied inferior turbinate
Platelet-rich fibrin
Turbinoplasty
Crustation
Hemostasis
Healing
title Effect of platelet-rich fibrin on wound healing, adhesions, and hemostasis after inferior turbinoplasty surgery
title_full Effect of platelet-rich fibrin on wound healing, adhesions, and hemostasis after inferior turbinoplasty surgery
title_fullStr Effect of platelet-rich fibrin on wound healing, adhesions, and hemostasis after inferior turbinoplasty surgery
title_full_unstemmed Effect of platelet-rich fibrin on wound healing, adhesions, and hemostasis after inferior turbinoplasty surgery
title_short Effect of platelet-rich fibrin on wound healing, adhesions, and hemostasis after inferior turbinoplasty surgery
title_sort effect of platelet rich fibrin on wound healing adhesions and hemostasis after inferior turbinoplasty surgery
topic Hypertrophied inferior turbinate
Platelet-rich fibrin
Turbinoplasty
Crustation
Hemostasis
Healing
url https://doi.org/10.1186/s43163-025-00764-z
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