Effect of platelet-rich fibrin on wound healing, adhesions, and hemostasis after inferior turbinoplasty surgery
Abstract Background Inferior turbinate enlargement is a prevalent cause of chronic nasal obstruction, often requiring surgical intervention when medical treatment fails. Platelet-rich fibrin (PRF) has been reported to mitigate post-operative complications following nasal surgeries. This work aims to...
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SpringerOpen
2025-02-01
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Series: | The Egyptian Journal of Otolaryngology |
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Online Access: | https://doi.org/10.1186/s43163-025-00764-z |
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author | Abdelhakim Fouad Ghallab Mohamed Fahmy Shendy Samer Badie Kamel Mohamed Ali Adam Mohamed Goda Elnems |
author_facet | Abdelhakim Fouad Ghallab Mohamed Fahmy Shendy Samer Badie Kamel Mohamed Ali Adam Mohamed Goda Elnems |
author_sort | Abdelhakim Fouad Ghallab |
collection | DOAJ |
description | Abstract Background Inferior turbinate enlargement is a prevalent cause of chronic nasal obstruction, often requiring surgical intervention when medical treatment fails. Platelet-rich fibrin (PRF) has been reported to mitigate post-operative complications following nasal surgeries. This work aims to evaluate the efficacy of PRF on hemostasis, adhesions, crust formation, and mucosal healing post-turbinoplasty. Results Demographic characters showed no statistical differences in age (p = 0.62) or gender (p = 0.342), but the mean operative time was significantly shorter in the non-PRF group (22.80 ± 2.02) compared to the PRF group (p > 0.001). Early hemostasis and prevention of crustation were significantly better in the PRF group (p = 0.03 and p = 0.024, respectively). No significant difference was observed regarding adhesions between the groups (p = 1). Conclusion The PRF membrane is an affordable and easy method that acts as a protective layer, reducing crusting, ensuring hemostasis, promoting healing by shortening the period of recovery post inferior turbinoplasty and so improving the quality of life of the patients. |
format | Article |
id | doaj-art-166e2c01582d4946a266e457f0c76d22 |
institution | Kabale University |
issn | 2090-8539 |
language | English |
publishDate | 2025-02-01 |
publisher | SpringerOpen |
record_format | Article |
series | The Egyptian Journal of Otolaryngology |
spelling | doaj-art-166e2c01582d4946a266e457f0c76d222025-02-09T12:08:59ZengSpringerOpenThe Egyptian Journal of Otolaryngology2090-85392025-02-014111810.1186/s43163-025-00764-zEffect of platelet-rich fibrin on wound healing, adhesions, and hemostasis after inferior turbinoplasty surgeryAbdelhakim Fouad Ghallab0Mohamed Fahmy Shendy1Samer Badie Kamel2Mohamed Ali Adam3Mohamed Goda Elnems4Otolaryngology Department, Faculty of Medicine, Benha UniversityOtolaryngology Department, Faculty of Medicine, Benha UniversityOtolaryngology Department, Faculty of Medicine, Benha UniversityOtolaryngology Department, Faculty of Medicine, Benha UniversityOtolaryngology Department, Faculty of Medicine, Benha UniversityAbstract Background Inferior turbinate enlargement is a prevalent cause of chronic nasal obstruction, often requiring surgical intervention when medical treatment fails. Platelet-rich fibrin (PRF) has been reported to mitigate post-operative complications following nasal surgeries. This work aims to evaluate the efficacy of PRF on hemostasis, adhesions, crust formation, and mucosal healing post-turbinoplasty. Results Demographic characters showed no statistical differences in age (p = 0.62) or gender (p = 0.342), but the mean operative time was significantly shorter in the non-PRF group (22.80 ± 2.02) compared to the PRF group (p > 0.001). Early hemostasis and prevention of crustation were significantly better in the PRF group (p = 0.03 and p = 0.024, respectively). No significant difference was observed regarding adhesions between the groups (p = 1). Conclusion The PRF membrane is an affordable and easy method that acts as a protective layer, reducing crusting, ensuring hemostasis, promoting healing by shortening the period of recovery post inferior turbinoplasty and so improving the quality of life of the patients.https://doi.org/10.1186/s43163-025-00764-zHypertrophied inferior turbinatePlatelet-rich fibrinTurbinoplastyCrustationHemostasisHealing |
spellingShingle | Abdelhakim Fouad Ghallab Mohamed Fahmy Shendy Samer Badie Kamel Mohamed Ali Adam Mohamed Goda Elnems Effect of platelet-rich fibrin on wound healing, adhesions, and hemostasis after inferior turbinoplasty surgery The Egyptian Journal of Otolaryngology Hypertrophied inferior turbinate Platelet-rich fibrin Turbinoplasty Crustation Hemostasis Healing |
title | Effect of platelet-rich fibrin on wound healing, adhesions, and hemostasis after inferior turbinoplasty surgery |
title_full | Effect of platelet-rich fibrin on wound healing, adhesions, and hemostasis after inferior turbinoplasty surgery |
title_fullStr | Effect of platelet-rich fibrin on wound healing, adhesions, and hemostasis after inferior turbinoplasty surgery |
title_full_unstemmed | Effect of platelet-rich fibrin on wound healing, adhesions, and hemostasis after inferior turbinoplasty surgery |
title_short | Effect of platelet-rich fibrin on wound healing, adhesions, and hemostasis after inferior turbinoplasty surgery |
title_sort | effect of platelet rich fibrin on wound healing adhesions and hemostasis after inferior turbinoplasty surgery |
topic | Hypertrophied inferior turbinate Platelet-rich fibrin Turbinoplasty Crustation Hemostasis Healing |
url | https://doi.org/10.1186/s43163-025-00764-z |
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