RGD-HSA-TAC nanoparticles targeted delivery of tacrolimus and attenuation of podocyte injury in diabetic kidney disease

RGD-HSA-TAC nanoparticles targeted delivery of tacrolimus and attenuation of podocyte injury in diabetic kidney disease

Abstract Background Diabetic kidney disease (DKD) is a prevalent and severe complication of diabetes and plays a pivotal role in the pathogenesis and progression of DKD. However, the current clinical application of the treatment methods does not yield effective results. Tacrolimus has been utilized...

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Bibliographic Details
Main Authors: Zhaochen Guo, Shaohui Gao, Feng Xu, Zige Chen, Qinger Wang, Zhaojie Liu, Ziyue Wang, Weisong Qin, Caihong Zeng, Zhihong Liu, Hao Bao
Format: Article
Language:English
Published: BMC 2025-02-01
Series:Journal of Nanobiotechnology
Subjects:
Diabetic kidney disease
Targeted delivery
Nanoparticle
HSA
Tacrolimus
Online Access:https://doi.org/10.1186/s12951-025-03108-4
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