The Accuracy of an Intraoperative Frozen Section for Premalignant Endometrial Pathology

OBJECTIVE: Abnormal uterine bleeding which is the most frequent complaint among pre- and postmenopausal women should be investigated to rule out endometrial cancer. An intra-operative frozen section can be taken to examine the suspicious of the malignancy. The study aims to investigate the accuracy...

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Bibliographic Details
Main Authors: Ergul Demircivi Bor, Esra Akdeniz, Yucel Nurettin Ceylan, Taner Gunay, Meryem Hocaoglu, Abdulkadir Turgut
Format: Article
Language:English
Published: Medical Network 2020-12-01
Series:Gynecology Obstetrics & Reproductive Medicine
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Online Access:https://gorm.com.tr/index.php/GORM/article/view/935
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Summary:OBJECTIVE: Abnormal uterine bleeding which is the most frequent complaint among pre- and postmenopausal women should be investigated to rule out endometrial cancer. An intra-operative frozen section can be taken to examine the suspicious of the malignancy. The study aims to investigate the accuracy of frozen section in suspicious of endometrial malignancy. STUDY DESIGN: Fifty patients with pre-malign endometrial pathology and malignant ultrasound characteristics were included in this study and their preoperative biopsy, frozen and postoperative pathological results were examined. RESULTS: The kappa coefficient between postoperative pathology and frozen section was 0.88 (p<0.05) and 95% confidence interval was (0.63-1.12). This indicates that the amount of agreement between the two tests was strong, thus the frozen section would be considered as a valid indicator of postoperative pathology results. CONCLUSIONS: Frozen section is a valuable method to investigate the suspicious of malignancy in endometrial pre-malign lesions.
ISSN:1300-4751
2602-4918