Association of ERCC2/XPD polymorphisms and the risk of head and neck carcinoma: a systematic review, meta-analysis, trial sequential analysis, network analysis, and functional effects

Association of ERCC2/XPD polymorphisms and the risk of head and neck carcinoma: a systematic review, meta-analysis, trial sequential analysis, network analysis, and functional effects

Abstract Objectives and aims The combination of genetic and environmental factors may contribute to the carcinogenesis of HNC. Despite the reported associations between xeroderma pigmentosum group D (XPD) polymorphisms and HNC, the results have been inconsistent, with different studies reporting var...

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Bibliographic Details
Main Authors: Mohammad Moslem Imani, Ali Ashabi, Farzad Rezaei, Atefe Saffar Shahroudi, Sadegh Kashkouli, Edris Sadeghi, Masoud Sadeghi
Format: Article
Language:English
Published: BMC 2025-02-01
Series:BMC Oral Health
Subjects:
Head and neck neoplasms
Xeroderma pigmentosum
XPD protein
ERCC2 protein
Meta-analysis
Online Access:https://doi.org/10.1186/s12903-025-05476-7
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