Sarcopenia in IBD patients and the role of nutritional and physical activity interventions in its management – a systematic review
Inflammatory Bowel Diseases (IBD), namely Ulcerative Colitis and Crohn’s Disease, are chronic, relapsing, inflammatory conditions of the gastrointestinal tract, with multifactorial pathophysiology. They are often complicated by sarcopenia, which is defined as a condition of skeletal muscle system c...
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| Format: | Article |
| Language: | English |
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Nicolaus Copernicus University in Toruń
2025-02-01
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| Series: | Quality in Sport |
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| Online Access: | https://apcz.umk.pl/QS/article/view/58221 |
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| author | Michalina Jurkiewicz Karolina Siembab Julia Białeta Katarzyna Rowińska Agnieszka Napieralska Wiktor Garbarczyk Albert Kapla Alicja Černohorská Daria Bednarczyk Wiktoria Pysiewicz |
| author_facet | Michalina Jurkiewicz Karolina Siembab Julia Białeta Katarzyna Rowińska Agnieszka Napieralska Wiktor Garbarczyk Albert Kapla Alicja Černohorská Daria Bednarczyk Wiktoria Pysiewicz |
| author_sort | Michalina Jurkiewicz |
| collection | DOAJ |
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Inflammatory Bowel Diseases (IBD), namely Ulcerative Colitis and Crohn’s Disease, are chronic, relapsing, inflammatory conditions of the gastrointestinal tract, with multifactorial pathophysiology. They are often complicated by sarcopenia, which is defined as a condition of skeletal muscle system characterized by a generalized loss of skeletal muscle mass and muscle function. Sarcopenia and pre-sarcopenic conditions are important to be diagnosed and maintained in the course of IBD, as they exert detrimental impact on the therapy outcomes. There is increased probability of therapy failure such as change of pharmacotherapy, hospitalization or surgical intervention, in individuals with sarcopenia. There are multiple mechanisms underlying this complication in IBD: e.g. malnutrition, disrupted gut microbiota, pharmacotherapy, and elevated inflammatory cytokines. Nevertheless, there are some possible interventions that can be undertaken to counteract this complication. Fundamental interventions in IBD-related sarcopenia are: accurate nutrition, micronutrient supplementation and properly adjusted physical activity. IBD patients should do 3-5 moderate-intensity trainings per week. Exercise programs should combine aerobic, resistance and flexibility exercises. Resistance training is the first-line therapy in management of sarcopenia. This kind of exercises was proven to improve muscle mass, strength and physical performance. Aerobic activity is also important as it enhances metabolic capacity of the muscles.
However, further research is required to define specific recommendations for nutritional and exercise interventions validated for the group of patients with IBD-related sarcopenia.
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| format | Article |
| id | doaj-art-19348e7c1c634e77925988b3b5eeb5cc |
| institution | Kabale University |
| issn | 2450-3118 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Nicolaus Copernicus University in Toruń |
| record_format | Article |
| series | Quality in Sport |
| spelling | doaj-art-19348e7c1c634e77925988b3b5eeb5cc2025-02-12T08:26:12ZengNicolaus Copernicus University in ToruńQuality in Sport2450-31182025-02-013810.12775/QS.2025.38.58221Sarcopenia in IBD patients and the role of nutritional and physical activity interventions in its management – a systematic reviewMichalina Jurkiewicz0https://orcid.org/0009-0005-3318-121XKarolina Siembab1https://orcid.org/0009-0000-9934-8741Julia Białeta2https://orcid.org/0009-0009-3140-4060Katarzyna Rowińska3https://orcid.org/0009-0002-7921-7167Agnieszka Napieralska4https://orcid.org/0009-0001-1163-8283Wiktor Garbarczyk5https://orcid.org/0009-0001-4107-6795Albert Kapla6https://orcid.org/0009-0004-0887-0825Alicja Černohorská7https://orcid.org/0009-0001-8230-2891Daria Bednarczyk8https://orcid.org/0009-0007-1006-4955Wiktoria Pysiewicz9https://orcid.org/0009-0002-3245-8609Central Teaching Hospital of Medical University of Łódź: Łódź, PLMaria Skłodowska-Curie Regional Specialist Hospital in ZgierzCentral Teaching Hospital of Medical University of ŁódźUniversity Clinical Hospital No. 2 of Medical University of ŁódźUniversity Clinical Hospital No. 2 of Medical University of ŁódźUniversity Clinical Hospital No. 2 of Medical University of ŁódźNZOZ Gajda-Med Medical GroupCentral Teaching Hospital of Medical University of ŁódźCentral Clinical Hospital of Medical University of WarsawNorbert Barlicki Memorial Teaching Hospital No. 1 of the Medical University of Lodz Inflammatory Bowel Diseases (IBD), namely Ulcerative Colitis and Crohn’s Disease, are chronic, relapsing, inflammatory conditions of the gastrointestinal tract, with multifactorial pathophysiology. They are often complicated by sarcopenia, which is defined as a condition of skeletal muscle system characterized by a generalized loss of skeletal muscle mass and muscle function. Sarcopenia and pre-sarcopenic conditions are important to be diagnosed and maintained in the course of IBD, as they exert detrimental impact on the therapy outcomes. There is increased probability of therapy failure such as change of pharmacotherapy, hospitalization or surgical intervention, in individuals with sarcopenia. There are multiple mechanisms underlying this complication in IBD: e.g. malnutrition, disrupted gut microbiota, pharmacotherapy, and elevated inflammatory cytokines. Nevertheless, there are some possible interventions that can be undertaken to counteract this complication. Fundamental interventions in IBD-related sarcopenia are: accurate nutrition, micronutrient supplementation and properly adjusted physical activity. IBD patients should do 3-5 moderate-intensity trainings per week. Exercise programs should combine aerobic, resistance and flexibility exercises. Resistance training is the first-line therapy in management of sarcopenia. This kind of exercises was proven to improve muscle mass, strength and physical performance. Aerobic activity is also important as it enhances metabolic capacity of the muscles. However, further research is required to define specific recommendations for nutritional and exercise interventions validated for the group of patients with IBD-related sarcopenia. https://apcz.umk.pl/QS/article/view/58221IBDsarcopeniaCrohn's diseasecolitis ulcerosainflammatory bowel disease |
| spellingShingle | Michalina Jurkiewicz Karolina Siembab Julia Białeta Katarzyna Rowińska Agnieszka Napieralska Wiktor Garbarczyk Albert Kapla Alicja Černohorská Daria Bednarczyk Wiktoria Pysiewicz Sarcopenia in IBD patients and the role of nutritional and physical activity interventions in its management – a systematic review Quality in Sport IBD sarcopenia Crohn's disease colitis ulcerosa inflammatory bowel disease |
| title | Sarcopenia in IBD patients and the role of nutritional and physical activity interventions in its management – a systematic review |
| title_full | Sarcopenia in IBD patients and the role of nutritional and physical activity interventions in its management – a systematic review |
| title_fullStr | Sarcopenia in IBD patients and the role of nutritional and physical activity interventions in its management – a systematic review |
| title_full_unstemmed | Sarcopenia in IBD patients and the role of nutritional and physical activity interventions in its management – a systematic review |
| title_short | Sarcopenia in IBD patients and the role of nutritional and physical activity interventions in its management – a systematic review |
| title_sort | sarcopenia in ibd patients and the role of nutritional and physical activity interventions in its management a systematic review |
| topic | IBD sarcopenia Crohn's disease colitis ulcerosa inflammatory bowel disease |
| url | https://apcz.umk.pl/QS/article/view/58221 |
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