Internet-based cognitive–behavioural therapy for insomnia (ICBT-i): a meta-analysis of randomised controlled trials

Objective To evaluate the effectiveness of internet-based cognitive–behavioural therapy for insomnia (ICBT-i) in adults.Design A meta-analysis of ICBT-i.Data sources Systematic searches of randomised controlled trials of ICBT-i were performed in the PubMed, EMBASE, PsycINFO and Cochrane Library data...

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Main Authors: Jia Chen, Juan Liu, Yuan-yuan Ye, Ni-ka Chen, Ling Lin, Ya-zhen Liu, Ying Lang, Xun-jun Li, Xin-ju Yang, Xiao-jiang Jiang
Format: Article
Language:English
Published: BMJ Publishing Group 2016-11-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/6/11/e010707.full
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author Jia Chen
Juan Liu
Yuan-yuan Ye
Ni-ka Chen
Ling Lin
Ya-zhen Liu
Ying Lang
Xun-jun Li
Xin-ju Yang
Xiao-jiang Jiang
author_facet Jia Chen
Juan Liu
Yuan-yuan Ye
Ni-ka Chen
Ling Lin
Ya-zhen Liu
Ying Lang
Xun-jun Li
Xin-ju Yang
Xiao-jiang Jiang
author_sort Jia Chen
collection DOAJ
description Objective To evaluate the effectiveness of internet-based cognitive–behavioural therapy for insomnia (ICBT-i) in adults.Design A meta-analysis of ICBT-i.Data sources Systematic searches of randomised controlled trials of ICBT-i were performed in the PubMed, EMBASE, PsycINFO and Cochrane Library databases up to 19 June 2016.Review method 2 reviewers independently performed study selection, quality assessment and data extraction. Outcomes of interest included sleep onset latency (SOL), total sleep time (TST), sleep efficiency (SE), wake after sleep onset (WASO), number of nocturnal awakenings (NWAK), and Insomnia Severity Index (ISI). RevMan 5.2 and Stata 13.0 meta-analysis software were used to perform statistical analysis.Results 14 records for 15 studies (1013 experimental group participants, 591 waiting list group participants) were included. The meta-analysis indicated that, at the post-test time point, SOL decreased by 18.41 min (95% CI 13.60 to 23.21), TST increased by 22.30 min (95% CI 16.38 to 28.23), SE increased by 9.58% (95% CI 7.30% to 11.85%), WASO decreased by 22.31 min (95% CI 13.50 to 31.11), NWAK decreased by 0.52 (95% CI 0.28 to 0.76), and ISI decreased by 5.88 points (95% CI 4.29 to 7.46). Additionally SOL, TST, SE, and WASO exhibited statistically significant improvements at follow-up versus before treatment.Conclusions ICBT-i is an effective treatment for adults with insomnia. This conclusion should be verified in further studies.
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spelling doaj-art-1b00091033da41ed85effc1f6b99c0712025-02-12T03:35:09ZengBMJ Publishing GroupBMJ Open2044-60552016-11-0161110.1136/bmjopen-2015-010707Internet-based cognitive–behavioural therapy for insomnia (ICBT-i): a meta-analysis of randomised controlled trialsJia Chen0Juan Liu1Yuan-yuan Ye2Ni-ka Chen3Ling Lin4Ya-zhen Liu5Ying Lang6Xun-jun Li7Xin-ju Yang8Xiao-jiang Jiang9Alnylam Pharmaceuticals, Cambridge, Massachusetts, USAassociate professor1Department of Neurology, Institute of Surgery Research, Daping Hospital, Third Military Medical University, Chongqing, China2Department of Neurology, PLA 187 Hospital, Haikou, ChinaDepartment of Respiratory and Critical Care Medicine, the Second Xiangya Hospital of Central South University, Changsha, Hunan, China1Department of Neurology, Institute of Surgery Research, Daping Hospital, Third Military Medical University, Chongqing, China1Department of Neurology, Institute of Surgery Research, Daping Hospital, Third Military Medical University, Chongqing, China1Department of Neurology, Institute of Surgery Research, Daping Hospital, Third Military Medical University, Chongqing, China1Department of Neurology, Institute of Surgery Research, Daping Hospital, Third Military Medical University, Chongqing, China1Department of Neurology, Institute of Surgery Research, Daping Hospital, Third Military Medical University, Chongqing, ChinaObjective To evaluate the effectiveness of internet-based cognitive–behavioural therapy for insomnia (ICBT-i) in adults.Design A meta-analysis of ICBT-i.Data sources Systematic searches of randomised controlled trials of ICBT-i were performed in the PubMed, EMBASE, PsycINFO and Cochrane Library databases up to 19 June 2016.Review method 2 reviewers independently performed study selection, quality assessment and data extraction. Outcomes of interest included sleep onset latency (SOL), total sleep time (TST), sleep efficiency (SE), wake after sleep onset (WASO), number of nocturnal awakenings (NWAK), and Insomnia Severity Index (ISI). RevMan 5.2 and Stata 13.0 meta-analysis software were used to perform statistical analysis.Results 14 records for 15 studies (1013 experimental group participants, 591 waiting list group participants) were included. The meta-analysis indicated that, at the post-test time point, SOL decreased by 18.41 min (95% CI 13.60 to 23.21), TST increased by 22.30 min (95% CI 16.38 to 28.23), SE increased by 9.58% (95% CI 7.30% to 11.85%), WASO decreased by 22.31 min (95% CI 13.50 to 31.11), NWAK decreased by 0.52 (95% CI 0.28 to 0.76), and ISI decreased by 5.88 points (95% CI 4.29 to 7.46). Additionally SOL, TST, SE, and WASO exhibited statistically significant improvements at follow-up versus before treatment.Conclusions ICBT-i is an effective treatment for adults with insomnia. This conclusion should be verified in further studies.https://bmjopen.bmj.com/content/6/11/e010707.full
spellingShingle Jia Chen
Juan Liu
Yuan-yuan Ye
Ni-ka Chen
Ling Lin
Ya-zhen Liu
Ying Lang
Xun-jun Li
Xin-ju Yang
Xiao-jiang Jiang
Internet-based cognitive–behavioural therapy for insomnia (ICBT-i): a meta-analysis of randomised controlled trials
BMJ Open
title Internet-based cognitive–behavioural therapy for insomnia (ICBT-i): a meta-analysis of randomised controlled trials
title_full Internet-based cognitive–behavioural therapy for insomnia (ICBT-i): a meta-analysis of randomised controlled trials
title_fullStr Internet-based cognitive–behavioural therapy for insomnia (ICBT-i): a meta-analysis of randomised controlled trials
title_full_unstemmed Internet-based cognitive–behavioural therapy for insomnia (ICBT-i): a meta-analysis of randomised controlled trials
title_short Internet-based cognitive–behavioural therapy for insomnia (ICBT-i): a meta-analysis of randomised controlled trials
title_sort internet based cognitive behavioural therapy for insomnia icbt i a meta analysis of randomised controlled trials
url https://bmjopen.bmj.com/content/6/11/e010707.full
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