Characterization of G2/M checkpoint classifier for personalized treatment in uterine corpus endometrial carcinoma

Characterization of G2/M checkpoint classifier for personalized treatment in uterine corpus endometrial carcinoma

Abstract Background Uterine Corpus Endometrial Carcinoma (UCEC) is a highly heterogeneous tumor, and limitations in current diagnostic methods, along with treatment resistance in some patients, pose significant challenges for managing UCEC. The excessive activation of G2/M checkpoint genes is a cruc...

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Bibliographic Details
Main Authors: Yiming Liu, Yusi Wang, Shu Tan, Xiaochen Shi, Jinglin Wen, Dejia Chen, Yue Zhao, Wenjing Pan, Zhaoyang Jia, Chunru Lu, Ge Lou
Format: Article
Language:English
Published: BMC 2025-02-01
Series:Cancer Cell International
Subjects:
Uterine Corpus Endometrial Carcinoma
G2/M Checkpoint
Precision Treatment
Drug Resistance
G2MCS
Online Access:https://doi.org/10.1186/s12935-025-03667-4
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