Differences in HIV infection trends in two regions of Cameroon with a longstanding HIV epidemic: insights from 2012 and 2022
IntroductionTo achieve the UNAIDS 95-95-95 target by 2025, it is of great importance to test and diagnose individuals infected with HIV; especially those residing in communities with limited access to health and in areas with a longstanding HIV epidemic, where the virus has been circulating since th...
Saved in:
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2025-02-01
|
| Series: | Frontiers in Public Health |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fpubh.2025.1517213/full |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1823856478727962624 |
|---|---|
| author | Yannick F. Ngoume Urmes C. Teagho Brice Eselacha Oumarou H. Goni Dell-Dylan Kenfack Mérimé Tchakoute Georges Nguefack-Tsague Marcel Tongo Marcel Tongo |
| author_facet | Yannick F. Ngoume Urmes C. Teagho Brice Eselacha Oumarou H. Goni Dell-Dylan Kenfack Mérimé Tchakoute Georges Nguefack-Tsague Marcel Tongo Marcel Tongo |
| author_sort | Yannick F. Ngoume |
| collection | DOAJ |
| description | IntroductionTo achieve the UNAIDS 95-95-95 target by 2025, it is of great importance to test and diagnose individuals infected with HIV; especially those residing in communities with limited access to health and in areas with a longstanding HIV epidemic, where the virus has been circulating since the early phase of the pandemic. In this regard, we determined the HIV prevalence in remote communities of the East and South administrative regions of Cameroon where the four cross-species SIV transmissions that gave rise to the four HIV-1 groups likely happened.MethodsWe did this in two different periods: 2012/2013 (Period 1; 4,435 participants enrolled in the East and 2,347 in the South) and 2021/2022 (Period 2; 2,203 participant enrolled in the East and 2,347 in the South) using HIV1/2 rapid assays and standard ELISAs and according to the WHO testing strategy.ResultsDuring Period 1, the HIV seroprevalence in the East was 6.9%. This prevalence had significantly decreased to 2.7% [Prevalence Difference or PD: 4.1 (3.1; 5.2); p < 0.001] by Period 2. Contrasting with these results, the HIV prevalence in the South during Period 1 was 5.5% and did not significantly change by Period 2 at 5.2% [PD: 0.3 (1.07;1.6); p = 0.67].ConclusionOur data suggest that HIV transmission in remote communities of the South administrative region of Cameroon has likely remained uncurbed over the past decade. As a result, this region should be prioritized in efforts to curb the spread of HIV and reduce its prevalence. |
| format | Article |
| id | doaj-art-1eddafb778184c0f8bf75572b2af9be9 |
| institution | Kabale University |
| issn | 2296-2565 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Public Health |
| spelling | doaj-art-1eddafb778184c0f8bf75572b2af9be92025-02-12T07:26:36ZengFrontiers Media S.A.Frontiers in Public Health2296-25652025-02-011310.3389/fpubh.2025.15172131517213Differences in HIV infection trends in two regions of Cameroon with a longstanding HIV epidemic: insights from 2012 and 2022Yannick F. Ngoume0Urmes C. Teagho1Brice Eselacha2Oumarou H. Goni3Dell-Dylan Kenfack4Mérimé Tchakoute5Georges Nguefack-Tsague6Marcel Tongo7Marcel Tongo8Centre of Research for Emerging and Re-Emerging Diseases/Institute of Medical Research and Studies of Medicinal Plants (CREMER/IMPM), Yaoundé, CameroonCentre of Research for Emerging and Re-Emerging Diseases/Institute of Medical Research and Studies of Medicinal Plants (CREMER/IMPM), Yaoundé, CameroonMinistry of Scientific Research and InnovationNational Institute of Cartography (INC), Yaoundé, CameroonCentre of Research for Emerging and Re-Emerging Diseases/Institute of Medical Research and Studies of Medicinal Plants (CREMER/IMPM), Yaoundé, CameroonCentre of Research for Emerging and Re-Emerging Diseases/Institute of Medical Research and Studies of Medicinal Plants (CREMER/IMPM), Yaoundé, CameroonProgrammes de Santé et Développement au Sein du Groupement de la Filière Bois du Cameroun (GFBC), Yaoundé, CameroonFaculty of Medicine and Biomedical Sciences, The University of Yaoundé I, Yaoundé, CameroonCentre of Research for Emerging and Re-Emerging Diseases/Institute of Medical Research and Studies of Medicinal Plants (CREMER/IMPM), Yaoundé, CameroonHIV Pathogenesis Programme, The Doris Duke Medical Research Institute, University of KwaZulu Natal, Durban, South AfricaIntroductionTo achieve the UNAIDS 95-95-95 target by 2025, it is of great importance to test and diagnose individuals infected with HIV; especially those residing in communities with limited access to health and in areas with a longstanding HIV epidemic, where the virus has been circulating since the early phase of the pandemic. In this regard, we determined the HIV prevalence in remote communities of the East and South administrative regions of Cameroon where the four cross-species SIV transmissions that gave rise to the four HIV-1 groups likely happened.MethodsWe did this in two different periods: 2012/2013 (Period 1; 4,435 participants enrolled in the East and 2,347 in the South) and 2021/2022 (Period 2; 2,203 participant enrolled in the East and 2,347 in the South) using HIV1/2 rapid assays and standard ELISAs and according to the WHO testing strategy.ResultsDuring Period 1, the HIV seroprevalence in the East was 6.9%. This prevalence had significantly decreased to 2.7% [Prevalence Difference or PD: 4.1 (3.1; 5.2); p < 0.001] by Period 2. Contrasting with these results, the HIV prevalence in the South during Period 1 was 5.5% and did not significantly change by Period 2 at 5.2% [PD: 0.3 (1.07;1.6); p = 0.67].ConclusionOur data suggest that HIV transmission in remote communities of the South administrative region of Cameroon has likely remained uncurbed over the past decade. As a result, this region should be prioritized in efforts to curb the spread of HIV and reduce its prevalence.https://www.frontiersin.org/articles/10.3389/fpubh.2025.1517213/fullHIV prevalenceCameroonHIV diagnosisHIV diversityHIV infection |
| spellingShingle | Yannick F. Ngoume Urmes C. Teagho Brice Eselacha Oumarou H. Goni Dell-Dylan Kenfack Mérimé Tchakoute Georges Nguefack-Tsague Marcel Tongo Marcel Tongo Differences in HIV infection trends in two regions of Cameroon with a longstanding HIV epidemic: insights from 2012 and 2022 Frontiers in Public Health HIV prevalence Cameroon HIV diagnosis HIV diversity HIV infection |
| title | Differences in HIV infection trends in two regions of Cameroon with a longstanding HIV epidemic: insights from 2012 and 2022 |
| title_full | Differences in HIV infection trends in two regions of Cameroon with a longstanding HIV epidemic: insights from 2012 and 2022 |
| title_fullStr | Differences in HIV infection trends in two regions of Cameroon with a longstanding HIV epidemic: insights from 2012 and 2022 |
| title_full_unstemmed | Differences in HIV infection trends in two regions of Cameroon with a longstanding HIV epidemic: insights from 2012 and 2022 |
| title_short | Differences in HIV infection trends in two regions of Cameroon with a longstanding HIV epidemic: insights from 2012 and 2022 |
| title_sort | differences in hiv infection trends in two regions of cameroon with a longstanding hiv epidemic insights from 2012 and 2022 |
| topic | HIV prevalence Cameroon HIV diagnosis HIV diversity HIV infection |
| url | https://www.frontiersin.org/articles/10.3389/fpubh.2025.1517213/full |
| work_keys_str_mv | AT yannickfngoume differencesinhivinfectiontrendsintworegionsofcameroonwithalongstandinghivepidemicinsightsfrom2012and2022 AT urmescteagho differencesinhivinfectiontrendsintworegionsofcameroonwithalongstandinghivepidemicinsightsfrom2012and2022 AT briceeselacha differencesinhivinfectiontrendsintworegionsofcameroonwithalongstandinghivepidemicinsightsfrom2012and2022 AT oumarouhgoni differencesinhivinfectiontrendsintworegionsofcameroonwithalongstandinghivepidemicinsightsfrom2012and2022 AT delldylankenfack differencesinhivinfectiontrendsintworegionsofcameroonwithalongstandinghivepidemicinsightsfrom2012and2022 AT merimetchakoute differencesinhivinfectiontrendsintworegionsofcameroonwithalongstandinghivepidemicinsightsfrom2012and2022 AT georgesnguefacktsague differencesinhivinfectiontrendsintworegionsofcameroonwithalongstandinghivepidemicinsightsfrom2012and2022 AT marceltongo differencesinhivinfectiontrendsintworegionsofcameroonwithalongstandinghivepidemicinsightsfrom2012and2022 AT marceltongo differencesinhivinfectiontrendsintworegionsofcameroonwithalongstandinghivepidemicinsightsfrom2012and2022 |