PHARMACEUTICAL TECHNIQUES FOR THE FABRICATION OF POOR WATERSOLUBLE DRUGS A REVIEW
Pharmaceutical technologies for increasing the solubility of drug substances have a prime role in its faster dissolution and maximum absorption in the systemic circulation. Majority of the drugs possesses low solubility leading to poor absorption and erratic bioavailability and thus failed to achie...
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| Format: | Article |
| Language: | English |
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Baqai University Press
2024-10-01
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| Series: | Baqai Journal of Health Sciences |
| Online Access: | https://journals.baqai.edu.pk/index.php/CS/article/view/101 |
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| _version_ | 1825197146538770432 |
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| author | Rabia Noor |
| author_facet | Rabia Noor |
| author_sort | Rabia Noor |
| collection | DOAJ |
| description |
Pharmaceutical technologies for increasing the solubility of drug substances have a prime role in its faster
dissolution and maximum absorption in the systemic circulation. Majority of the drugs possesses low
solubility leading to poor absorption and erratic bioavailability and thus failed to achieve a desired
pharmacological response. Therefore formulation scientists have adopted various techniques to overcome
solubility and bioavailability issues following oral administration. The selection of technique is primarily
based on the physicochemical characteristics of drug and dosage form. The present review highlights the
importance of solubility with a brief description of conventional and novel approaches that could be used
for solubility enhancement
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| format | Article |
| id | doaj-art-1f2ddbbfc0e146c7b798f9abb4e56a40 |
| institution | Kabale University |
| issn | 2312-4423 2312-6884 |
| language | English |
| publishDate | 2024-10-01 |
| publisher | Baqai University Press |
| record_format | Article |
| series | Baqai Journal of Health Sciences |
| spelling | doaj-art-1f2ddbbfc0e146c7b798f9abb4e56a402025-02-11T18:45:37ZengBaqai University PressBaqai Journal of Health Sciences2312-44232312-68842024-10-01211PHARMACEUTICAL TECHNIQUES FOR THE FABRICATION OF POOR WATERSOLUBLE DRUGS A REVIEWRabia Noor Pharmaceutical technologies for increasing the solubility of drug substances have a prime role in its faster dissolution and maximum absorption in the systemic circulation. Majority of the drugs possesses low solubility leading to poor absorption and erratic bioavailability and thus failed to achieve a desired pharmacological response. Therefore formulation scientists have adopted various techniques to overcome solubility and bioavailability issues following oral administration. The selection of technique is primarily based on the physicochemical characteristics of drug and dosage form. The present review highlights the importance of solubility with a brief description of conventional and novel approaches that could be used for solubility enhancement https://journals.baqai.edu.pk/index.php/CS/article/view/101 |
| spellingShingle | Rabia Noor PHARMACEUTICAL TECHNIQUES FOR THE FABRICATION OF POOR WATERSOLUBLE DRUGS A REVIEW Baqai Journal of Health Sciences |
| title | PHARMACEUTICAL TECHNIQUES FOR THE FABRICATION OF POOR WATERSOLUBLE DRUGS A REVIEW |
| title_full | PHARMACEUTICAL TECHNIQUES FOR THE FABRICATION OF POOR WATERSOLUBLE DRUGS A REVIEW |
| title_fullStr | PHARMACEUTICAL TECHNIQUES FOR THE FABRICATION OF POOR WATERSOLUBLE DRUGS A REVIEW |
| title_full_unstemmed | PHARMACEUTICAL TECHNIQUES FOR THE FABRICATION OF POOR WATERSOLUBLE DRUGS A REVIEW |
| title_short | PHARMACEUTICAL TECHNIQUES FOR THE FABRICATION OF POOR WATERSOLUBLE DRUGS A REVIEW |
| title_sort | pharmaceutical techniques for the fabrication of poor watersoluble drugs a review |
| url | https://journals.baqai.edu.pk/index.php/CS/article/view/101 |
| work_keys_str_mv | AT rabianoor pharmaceuticaltechniquesforthefabricationofpoorwatersolubledrugsareview |