A unique coexistence of a plurihormonal pituitary adenoma with granulomatous hypophysitis
Dual pathology in the pituitary gland is a unique phenomenon. Coexistence of a pituitary adenoma with primary hypophysitis has been reported rarely with very few cases in the literature. Among the primary hypophysitis, primary granulomatous subtype has been proposed to be idiopathic and autoimmune i...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2023-07-01
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| Series: | Indian Journal of Pathology and Microbiology |
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| Online Access: | https://journals.lww.com/10.4103/ijpm.ijpm_439_21 |
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| _version_ | 1825206059707400192 |
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| author | Sanjiban Patra Priti Trivedi |
| author_facet | Sanjiban Patra Priti Trivedi |
| author_sort | Sanjiban Patra |
| collection | DOAJ |
| description | Dual pathology in the pituitary gland is a unique phenomenon. Coexistence of a pituitary adenoma with primary hypophysitis has been reported rarely with very few cases in the literature. Among the primary hypophysitis, primary granulomatous subtype has been proposed to be idiopathic and autoimmune in nature. Plurihormonal pituitary adenomas produce hormones of more than one different pituitary cell lineage. Pituitary adenoma with a single hormonal content has been documented with concurrent primary granulomatous hypophysitis. The present case describes the unique coexistence of a plurihormonal adenoma showing somatotroph, lactotroph, and corticotroph lineage with primary granulomatous inflammation in the sellar region in a 36-year-old woman. |
| format | Article |
| id | doaj-art-1ff07bb414424da28ef7888d9779b11a |
| institution | Kabale University |
| issn | 0377-4929 |
| language | English |
| publishDate | 2023-07-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Pathology and Microbiology |
| spelling | doaj-art-1ff07bb414424da28ef7888d9779b11a2025-02-07T13:34:40ZengWolters Kluwer Medknow PublicationsIndian Journal of Pathology and Microbiology0377-49292023-07-0166361862010.4103/ijpm.ijpm_439_21A unique coexistence of a plurihormonal pituitary adenoma with granulomatous hypophysitisSanjiban PatraPriti TrivediDual pathology in the pituitary gland is a unique phenomenon. Coexistence of a pituitary adenoma with primary hypophysitis has been reported rarely with very few cases in the literature. Among the primary hypophysitis, primary granulomatous subtype has been proposed to be idiopathic and autoimmune in nature. Plurihormonal pituitary adenomas produce hormones of more than one different pituitary cell lineage. Pituitary adenoma with a single hormonal content has been documented with concurrent primary granulomatous hypophysitis. The present case describes the unique coexistence of a plurihormonal adenoma showing somatotroph, lactotroph, and corticotroph lineage with primary granulomatous inflammation in the sellar region in a 36-year-old woman.https://journals.lww.com/10.4103/ijpm.ijpm_439_21immunohistochemistrypituitary adenomaplurihormonalprimary granulomatous hypophysitis |
| spellingShingle | Sanjiban Patra Priti Trivedi A unique coexistence of a plurihormonal pituitary adenoma with granulomatous hypophysitis Indian Journal of Pathology and Microbiology immunohistochemistry pituitary adenoma plurihormonal primary granulomatous hypophysitis |
| title | A unique coexistence of a plurihormonal pituitary adenoma with granulomatous hypophysitis |
| title_full | A unique coexistence of a plurihormonal pituitary adenoma with granulomatous hypophysitis |
| title_fullStr | A unique coexistence of a plurihormonal pituitary adenoma with granulomatous hypophysitis |
| title_full_unstemmed | A unique coexistence of a plurihormonal pituitary adenoma with granulomatous hypophysitis |
| title_short | A unique coexistence of a plurihormonal pituitary adenoma with granulomatous hypophysitis |
| title_sort | unique coexistence of a plurihormonal pituitary adenoma with granulomatous hypophysitis |
| topic | immunohistochemistry pituitary adenoma plurihormonal primary granulomatous hypophysitis |
| url | https://journals.lww.com/10.4103/ijpm.ijpm_439_21 |
| work_keys_str_mv | AT sanjibanpatra auniquecoexistenceofaplurihormonalpituitaryadenomawithgranulomatoushypophysitis AT prititrivedi auniquecoexistenceofaplurihormonalpituitaryadenomawithgranulomatoushypophysitis AT sanjibanpatra uniquecoexistenceofaplurihormonalpituitaryadenomawithgranulomatoushypophysitis AT prititrivedi uniquecoexistenceofaplurihormonalpituitaryadenomawithgranulomatoushypophysitis |