Evidence based use of antibiotics in epidemic keratoconjunctivitis to prevent development of microbial resistance
Aim: It was thought that resistance acquired during treatment of systemic diseases can lead to resistant bacteria in eye infections. However, evidences are showing emergence of bacterial resistance owing to prior topical antibiotic usage. In the current study, we intended to promote evidence-based u...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2025-01-01
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| Series: | Journal of Family Medicine and Primary Care |
| Subjects: | |
| Online Access: | https://journals.lww.com/10.4103/jfmpc.jfmpc_1123_24 |
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| _version_ | 1823858101986525184 |
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| author | Shalini Kumari Imsensenba Longkumer Mamta Sharma Shashank Tripathi |
| author_facet | Shalini Kumari Imsensenba Longkumer Mamta Sharma Shashank Tripathi |
| author_sort | Shalini Kumari |
| collection | DOAJ |
| description | Aim:
It was thought that resistance acquired during treatment of systemic diseases can lead to resistant bacteria in eye infections. However, evidences are showing emergence of bacterial resistance owing to prior topical antibiotic usage. In the current study, we intended to promote evidence-based usage of antibiotics during outbreak of epidemic keratoconjunctivitis.
Methods:
A descriptive study was designed. First 50 patients who visited the outpatient department of ophthalmology with signs and symptoms of EKC during the outbreak in the months of July-August, 2023 in a tertiary hospital in northern India were included in the study. Prior usage of topical antibiotics during this epidemic outbreak was the exclusion criteria. Conjunctival swabs were taken and subjected to Gram staining and Culture and sensitivity, for any bacterial infection.
Results:
Only two slides of gram stain showed gram-positive cocci. These two samples were positive for Methicillin resistant Staphylococcs Aureus (MRSA). Rest of the 48 samples were negative for any bacterial growth. P value for no growth in bacterial cultures was <0.05, which is significant.
Conclusions:
Our study suggests restrain from overusage of topical antibiotics in outbreaks of EKC until microbiological outcomes suggest otherwise. In view of presence of MRSA in neo-natal sample, and its known serious complications, we suggest prophylactic use of topical antibiotic and its modifications once reports of culture and sensitivity are available. |
| format | Article |
| id | doaj-art-2014cf5ebaaa40a2a555bf1f718c8ae9 |
| institution | Kabale University |
| issn | 2249-4863 2278-7135 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Family Medicine and Primary Care |
| spelling | doaj-art-2014cf5ebaaa40a2a555bf1f718c8ae92025-02-11T13:58:03ZengWolters Kluwer Medknow PublicationsJournal of Family Medicine and Primary Care2249-48632278-71352025-01-0114141241810.4103/jfmpc.jfmpc_1123_24Evidence based use of antibiotics in epidemic keratoconjunctivitis to prevent development of microbial resistanceShalini KumariImsensenba LongkumerMamta SharmaShashank TripathiAim: It was thought that resistance acquired during treatment of systemic diseases can lead to resistant bacteria in eye infections. However, evidences are showing emergence of bacterial resistance owing to prior topical antibiotic usage. In the current study, we intended to promote evidence-based usage of antibiotics during outbreak of epidemic keratoconjunctivitis. Methods: A descriptive study was designed. First 50 patients who visited the outpatient department of ophthalmology with signs and symptoms of EKC during the outbreak in the months of July-August, 2023 in a tertiary hospital in northern India were included in the study. Prior usage of topical antibiotics during this epidemic outbreak was the exclusion criteria. Conjunctival swabs were taken and subjected to Gram staining and Culture and sensitivity, for any bacterial infection. Results: Only two slides of gram stain showed gram-positive cocci. These two samples were positive for Methicillin resistant Staphylococcs Aureus (MRSA). Rest of the 48 samples were negative for any bacterial growth. P value for no growth in bacterial cultures was <0.05, which is significant. Conclusions: Our study suggests restrain from overusage of topical antibiotics in outbreaks of EKC until microbiological outcomes suggest otherwise. In view of presence of MRSA in neo-natal sample, and its known serious complications, we suggest prophylactic use of topical antibiotic and its modifications once reports of culture and sensitivity are available.https://journals.lww.com/10.4103/jfmpc.jfmpc_1123_24antibiotic resistancebacteriaepidemic keratoconjunctivitisfluoroquinolonesocular infections |
| spellingShingle | Shalini Kumari Imsensenba Longkumer Mamta Sharma Shashank Tripathi Evidence based use of antibiotics in epidemic keratoconjunctivitis to prevent development of microbial resistance Journal of Family Medicine and Primary Care antibiotic resistance bacteria epidemic keratoconjunctivitis fluoroquinolones ocular infections |
| title | Evidence based use of antibiotics in epidemic keratoconjunctivitis to prevent development of microbial resistance |
| title_full | Evidence based use of antibiotics in epidemic keratoconjunctivitis to prevent development of microbial resistance |
| title_fullStr | Evidence based use of antibiotics in epidemic keratoconjunctivitis to prevent development of microbial resistance |
| title_full_unstemmed | Evidence based use of antibiotics in epidemic keratoconjunctivitis to prevent development of microbial resistance |
| title_short | Evidence based use of antibiotics in epidemic keratoconjunctivitis to prevent development of microbial resistance |
| title_sort | evidence based use of antibiotics in epidemic keratoconjunctivitis to prevent development of microbial resistance |
| topic | antibiotic resistance bacteria epidemic keratoconjunctivitis fluoroquinolones ocular infections |
| url | https://journals.lww.com/10.4103/jfmpc.jfmpc_1123_24 |
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