Mechanism study on the enhancement of bile acid-binding capacity in corn by-product juice via Lactiplantibacillus plantarum HY127 fermentation
Hyperlipidemia is a common endocrine metabolic disease in humans. Long-term medications often have adverse effects, making the search for safer and more effective treatments crucial. This study aimed to explore the impacts and mechanisms of Lactiplantibacillus plantarum HY127 fermentation on enhanci...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-01-01
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| Series: | Food Chemistry: X |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2590157524009994 |
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| author | Huanyong Lv Xiaohui Tang Jian Zhang Menghan Ma Xinyi Li Zhenjie Zheng Yunhe Xu Lili Zhang |
| author_facet | Huanyong Lv Xiaohui Tang Jian Zhang Menghan Ma Xinyi Li Zhenjie Zheng Yunhe Xu Lili Zhang |
| author_sort | Huanyong Lv |
| collection | DOAJ |
| description | Hyperlipidemia is a common endocrine metabolic disease in humans. Long-term medications often have adverse effects, making the search for safer and more effective treatments crucial. This study aimed to explore the impacts and mechanisms of Lactiplantibacillus plantarum HY127 fermentation on enhancing bile acid-binding capacity (BABC). We fermented corn by-product juice (CBJ) by HY127 and investigated the BABC of HY127 bacterial cells and their metabolites. Our results indicated that HY127 cells (95.25 %) played a major role in enhancing BABC, with metabolites (31.50 %–66.41 %) also contributing. Compared to unfermented CBJ, the contents of phenolics, flavonoids, polysaccharides, and organic acids were significantly higher. Non-targeted metabolomics revealed upregulated amino acids, alkaloids, terpenoids, and other bioactive substances associated with BABC in the supernatant. This study confirmed that HY127 fermentation enhances the BABC of CBJ (increased by 32.02 %–78.76 %), providing a research foundation and technical reference for the development of LAB-fermented corn by-product beverages with hypolipidemic activities. |
| format | Article |
| id | doaj-art-2c47069ed99d4cd0ace43a8845077c85 |
| institution | Kabale University |
| issn | 2590-1575 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Food Chemistry: X |
| spelling | doaj-art-2c47069ed99d4cd0ace43a8845077c852025-02-12T05:32:00ZengElsevierFood Chemistry: X2590-15752025-01-0125102111Mechanism study on the enhancement of bile acid-binding capacity in corn by-product juice via Lactiplantibacillus plantarum HY127 fermentationHuanyong Lv0Xiaohui Tang1Jian Zhang2Menghan Ma3Xinyi Li4Zhenjie Zheng5Yunhe Xu6Lili Zhang7School of Food and Health, Jinzhou Medical University, Jinzhou 121000, China; Liaoning Agricultural Vocational and Technical College, Yingkou 115007, ChinaSchool of Food and Health, Jinzhou Medical University, Jinzhou 121000, ChinaDepartment of Biology, University of British Columbia, Okanagan, Kelowna, BC V1V 1V7, Canada; Faculty of Agronomy, Jilin Agricultural University, Changchun 130118, ChinaSchool of Food and Health, Jinzhou Medical University, Jinzhou 121000, ChinaSchool of Food and Health, Jinzhou Medical University, Jinzhou 121000, ChinaSchool of Food and Health, Jinzhou Medical University, Jinzhou 121000, ChinaSchool of Food and Health, Jinzhou Medical University, Jinzhou 121000, China; Corresponding authors.School of Food and Health, Jinzhou Medical University, Jinzhou 121000, China; Corresponding authors.Hyperlipidemia is a common endocrine metabolic disease in humans. Long-term medications often have adverse effects, making the search for safer and more effective treatments crucial. This study aimed to explore the impacts and mechanisms of Lactiplantibacillus plantarum HY127 fermentation on enhancing bile acid-binding capacity (BABC). We fermented corn by-product juice (CBJ) by HY127 and investigated the BABC of HY127 bacterial cells and their metabolites. Our results indicated that HY127 cells (95.25 %) played a major role in enhancing BABC, with metabolites (31.50 %–66.41 %) also contributing. Compared to unfermented CBJ, the contents of phenolics, flavonoids, polysaccharides, and organic acids were significantly higher. Non-targeted metabolomics revealed upregulated amino acids, alkaloids, terpenoids, and other bioactive substances associated with BABC in the supernatant. This study confirmed that HY127 fermentation enhances the BABC of CBJ (increased by 32.02 %–78.76 %), providing a research foundation and technical reference for the development of LAB-fermented corn by-product beverages with hypolipidemic activities.http://www.sciencedirect.com/science/article/pii/S2590157524009994L. plantarum fermentationCorn by-product juiceBile acid binding capacityHyperlipidemiaMetabolomics |
| spellingShingle | Huanyong Lv Xiaohui Tang Jian Zhang Menghan Ma Xinyi Li Zhenjie Zheng Yunhe Xu Lili Zhang Mechanism study on the enhancement of bile acid-binding capacity in corn by-product juice via Lactiplantibacillus plantarum HY127 fermentation Food Chemistry: X L. plantarum fermentation Corn by-product juice Bile acid binding capacity Hyperlipidemia Metabolomics |
| title | Mechanism study on the enhancement of bile acid-binding capacity in corn by-product juice via Lactiplantibacillus plantarum HY127 fermentation |
| title_full | Mechanism study on the enhancement of bile acid-binding capacity in corn by-product juice via Lactiplantibacillus plantarum HY127 fermentation |
| title_fullStr | Mechanism study on the enhancement of bile acid-binding capacity in corn by-product juice via Lactiplantibacillus plantarum HY127 fermentation |
| title_full_unstemmed | Mechanism study on the enhancement of bile acid-binding capacity in corn by-product juice via Lactiplantibacillus plantarum HY127 fermentation |
| title_short | Mechanism study on the enhancement of bile acid-binding capacity in corn by-product juice via Lactiplantibacillus plantarum HY127 fermentation |
| title_sort | mechanism study on the enhancement of bile acid binding capacity in corn by product juice via lactiplantibacillus plantarum hy127 fermentation |
| topic | L. plantarum fermentation Corn by-product juice Bile acid binding capacity Hyperlipidemia Metabolomics |
| url | http://www.sciencedirect.com/science/article/pii/S2590157524009994 |
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