A Bird’s-Eye Overview of Leptin and Female Reproduction —with Mammalian Comparisons
Leptin, a key regulator of reproductive physiology, influences various processes in vertebrates, including oocyte proliferation, embryogenesis, the onset of puberty, ovarian function, and follicle development. In mammals, leptin affects steroidogenesis, folliculogenesis, a...
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| Format: | Article |
| Language: | English |
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Japan Poultry Science Association
2025-02-01
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| Series: | The Journal of Poultry Science |
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| Online Access: | https://www.jstage.jst.go.jp/article/jpsa/62/0/62_2025007/_html/-char/en |
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| author | Sadequllah Ahmadi Takeshi Ohkubo |
| author_facet | Sadequllah Ahmadi Takeshi Ohkubo |
| author_sort | Sadequllah Ahmadi |
| collection | DOAJ |
| description | Leptin, a key regulator of reproductive physiology, influences various processes in vertebrates, including oocyte proliferation, embryogenesis, the onset of puberty, ovarian function, and follicle development. In mammals, leptin affects steroidogenesis, folliculogenesis, and hormonal regulation through the hypothalamic-pituitary-gonadal axis. Instead, in avian species, leptin-controlled mechanisms are poorly understood, because birds do not produce leptin in adipocytes. In birds, leptin is expressed in the brain, pituitary glands, and gonads, where it enhances ovarian function and egg-laying performance, particularly during feed deprivation. In this review, we discuss and summarize the recently discovered role of leptin in regulating ovarian function during different life stages in birds and compare it with its function in mammals. |
| format | Article |
| id | doaj-art-2df0a9478cde4783a307b6357fad05ca |
| institution | Kabale University |
| issn | 1346-7395 1349-0486 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Japan Poultry Science Association |
| record_format | Article |
| series | The Journal of Poultry Science |
| spelling | doaj-art-2df0a9478cde4783a307b6357fad05ca2025-02-12T05:23:29ZengJapan Poultry Science AssociationThe Journal of Poultry Science1346-73951349-04862025-02-0162010.2141/jpsa.2025007jpsaA Bird’s-Eye Overview of Leptin and Female Reproduction —with Mammalian ComparisonsSadequllah Ahmadi0Takeshi Ohkubo1College of Agriculture, Ibaraki University, 3-21-1 Chuo, Ami, Ibaraki 300-0393, JapanCollege of Agriculture, Ibaraki University, 3-21-1 Chuo, Ami, Ibaraki 300-0393, JapanLeptin, a key regulator of reproductive physiology, influences various processes in vertebrates, including oocyte proliferation, embryogenesis, the onset of puberty, ovarian function, and follicle development. In mammals, leptin affects steroidogenesis, folliculogenesis, and hormonal regulation through the hypothalamic-pituitary-gonadal axis. Instead, in avian species, leptin-controlled mechanisms are poorly understood, because birds do not produce leptin in adipocytes. In birds, leptin is expressed in the brain, pituitary glands, and gonads, where it enhances ovarian function and egg-laying performance, particularly during feed deprivation. In this review, we discuss and summarize the recently discovered role of leptin in regulating ovarian function during different life stages in birds and compare it with its function in mammals.https://www.jstage.jst.go.jp/article/jpsa/62/0/62_2025007/_html/-char/enbirdsleptinmammalsovaryreproduction |
| spellingShingle | Sadequllah Ahmadi Takeshi Ohkubo A Bird’s-Eye Overview of Leptin and Female Reproduction —with Mammalian Comparisons The Journal of Poultry Science birds leptin mammals ovary reproduction |
| title | A Bird’s-Eye Overview of Leptin and Female Reproduction —with Mammalian Comparisons |
| title_full | A Bird’s-Eye Overview of Leptin and Female Reproduction —with Mammalian Comparisons |
| title_fullStr | A Bird’s-Eye Overview of Leptin and Female Reproduction —with Mammalian Comparisons |
| title_full_unstemmed | A Bird’s-Eye Overview of Leptin and Female Reproduction —with Mammalian Comparisons |
| title_short | A Bird’s-Eye Overview of Leptin and Female Reproduction —with Mammalian Comparisons |
| title_sort | bird s eye overview of leptin and female reproduction with mammalian comparisons |
| topic | birds leptin mammals ovary reproduction |
| url | https://www.jstage.jst.go.jp/article/jpsa/62/0/62_2025007/_html/-char/en |
| work_keys_str_mv | AT sadequllahahmadi abirdseyeoverviewofleptinandfemalereproductionwithmammaliancomparisons AT takeshiohkubo abirdseyeoverviewofleptinandfemalereproductionwithmammaliancomparisons AT sadequllahahmadi birdseyeoverviewofleptinandfemalereproductionwithmammaliancomparisons AT takeshiohkubo birdseyeoverviewofleptinandfemalereproductionwithmammaliancomparisons |