The effect of anti mullerian hormone and follicle stimulating hormone discordance on oocyte quality and live birth rates

Evaluating ovarian reserve is crucial in infertility treatment to determine the appropriate approach and predict success rates. Anti-Mullerian Hormone (AMH) and Follicle-Stimulating Hormone (FSH) are key parameters commonly used for this purpose, and they usually yield consistent results. A good ova...

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Main Authors: Seray Kaya, Murat Genc, Bensu Bulut, Medine Akkan Oz, Mustafa Ozturk
Format: Article
Language:English
Published: Society of Turaz Bilim 2024-04-01
Series:Medicine Science
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Online Access:https://www.medicinescience.org/?mno=224959
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Summary:Evaluating ovarian reserve is crucial in infertility treatment to determine the appropriate approach and predict success rates. Anti-Mullerian Hormone (AMH) and Follicle-Stimulating Hormone (FSH) are key parameters commonly used for this purpose, and they usually yield consistent results. A good ovarian reserve is typically indicated when FSH is below 10 IU/ml and AMH is 1 ng/ml or higher. However, in clinical practice, these parameters often conflict, with one suggesting a good ovarian reserve while the other indicates a diminished one. AMH is known to predict oocyte count effectively, but its ability to predict live births is weaker. This study aimed to investigate which parameter is more useful in predicting oocyte count, quality, and live birth outcomes in cases of discordance. This retrospective study was conducted on 82 patients who sought infertility treatment at Assisted Reproductive Techniques Center of Gulhane Training and Research Hospital between January 1, 2016, and December 31, 2020. Data collected included age, AMH and FSH levels, number of retrieved oocytes, mature (M2) oocytes, pregnancy outcomes, and embryos obtained. Statistical analyses were performed using SPSS 25.0. Normal distribution was assessed using the Kolmogorov-Smirnov test and graphical methods. Independent t-tests and One-Way ANOVA were used for normally distributed data, with a significance level set at p=0.05. Patients were divided into two groups: AMH [Med-Science 2024; 13(4.000): 1001-6]
ISSN:2147-0634