Effect of Basal Testosterone and Dehydroepiandrosterone Sulphate Levels on in Vitro Fertilization Outcome in Normoresponders

OBJECTIVE: The purpose of the present study is to evaluate the predictive value of basal total testosterone (total-T) and dehydroepiandrosterone sulphate (DHEAS) levels in normoresponder patients undergoing IVF-ET. STUDY DESIGN: A total of 60 normoresponder infertile women, scheduled to undergo the...

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Main Authors: İnci Kahyaoğlu, Nafiye Yılmaz, Serkan Kahyaoğlu, Ayten Türkkanı, Mahmut Nedim Çiçek, Leyla Mollamahmutoğlu
Format: Article
Language:English
Published: Medical Network 2013-12-01
Series:Gynecology Obstetrics & Reproductive Medicine
Subjects:
Online Access:https://gorm.com.tr/index.php/GORM/article/view/212
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author İnci Kahyaoğlu
Nafiye Yılmaz
Serkan Kahyaoğlu
Ayten Türkkanı
Mahmut Nedim Çiçek
Leyla Mollamahmutoğlu
author_facet İnci Kahyaoğlu
Nafiye Yılmaz
Serkan Kahyaoğlu
Ayten Türkkanı
Mahmut Nedim Çiçek
Leyla Mollamahmutoğlu
author_sort İnci Kahyaoğlu
collection DOAJ
description OBJECTIVE: The purpose of the present study is to evaluate the predictive value of basal total testosterone (total-T) and dehydroepiandrosterone sulphate (DHEAS) levels in normoresponder patients undergoing IVF-ET. STUDY DESIGN: A total of 60 normoresponder infertile women, scheduled to undergo their first IVF/ET cycle were enrolled in this study. Day 2-4 basal concentrations of FSH, LH, E2, total testosterone, DHEAS and antral follicle count (AFC) were determined in preceding cycle. RESULTS: No significant difference was found between pregnant and non-pregnant groups regarding the AFC, hormone and controlled ovarian hyperstimulation (COH) parameters (total dose of gonadotrophins (1995.7±851.1 vs 2296.4±845.3 IU), >14 mm follicles (9.3±3.1 vs 7.3±3.9), retrieved oocytes (12.4±5.1 vs 8.7±6.1) or number of good quality embryos (7.4±3.7 vs 4,4±3.6) (p>0.05). Testosterone and DHEAS was not correlated with COH parameters (p>0.05). CONCLUSION: There is no correlation between testosterone and DHEAS levels and COH parameters in normoresponder IVF patients.
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publishDate 2013-12-01
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series Gynecology Obstetrics & Reproductive Medicine
spelling doaj-art-2e5ae768addd48b498927a4ca5d9c2102025-02-11T21:22:13ZengMedical NetworkGynecology Obstetrics & Reproductive Medicine1300-47512602-49182013-12-01193150Effect of Basal Testosterone and Dehydroepiandrosterone Sulphate Levels on in Vitro Fertilization Outcome in Normorespondersİnci Kahyaoğlu0Nafiye Yılmaz1Serkan Kahyaoğlu2Ayten Türkkanı3Mahmut Nedim Çiçek4Leyla Mollamahmutoğlu5Etlik Zübeyde Hanım Women’s Health Teaching and Research Hospital, Department of IVF, AnkaraZekai Tahir Burak Women's Health Education and Research Hospital, Department of IVF, AnkaraZekai Tahir Burak Women's Health Education and Research Hospital, Department of IVF, AnkaraEtlik Zübeyde Hanım Women’s Health Teaching and Research Hospital, Department of IVF, AnkaraZekai Tahir Burak Women's Health Education and Research Hospital, Department of IVF, AnkaraEtlik Zübeyde Hanım Women’s Health Teaching and Research Hospital, Department of IVF, Ankara OBJECTIVE: The purpose of the present study is to evaluate the predictive value of basal total testosterone (total-T) and dehydroepiandrosterone sulphate (DHEAS) levels in normoresponder patients undergoing IVF-ET. STUDY DESIGN: A total of 60 normoresponder infertile women, scheduled to undergo their first IVF/ET cycle were enrolled in this study. Day 2-4 basal concentrations of FSH, LH, E2, total testosterone, DHEAS and antral follicle count (AFC) were determined in preceding cycle. RESULTS: No significant difference was found between pregnant and non-pregnant groups regarding the AFC, hormone and controlled ovarian hyperstimulation (COH) parameters (total dose of gonadotrophins (1995.7±851.1 vs 2296.4±845.3 IU), >14 mm follicles (9.3±3.1 vs 7.3±3.9), retrieved oocytes (12.4±5.1 vs 8.7±6.1) or number of good quality embryos (7.4±3.7 vs 4,4±3.6) (p>0.05). Testosterone and DHEAS was not correlated with COH parameters (p>0.05). CONCLUSION: There is no correlation between testosterone and DHEAS levels and COH parameters in normoresponder IVF patients. https://gorm.com.tr/index.php/GORM/article/view/212AndrogenNormoresponderIn vitro fertilization
spellingShingle İnci Kahyaoğlu
Nafiye Yılmaz
Serkan Kahyaoğlu
Ayten Türkkanı
Mahmut Nedim Çiçek
Leyla Mollamahmutoğlu
Effect of Basal Testosterone and Dehydroepiandrosterone Sulphate Levels on in Vitro Fertilization Outcome in Normoresponders
Gynecology Obstetrics & Reproductive Medicine
Androgen
Normoresponder
In vitro fertilization
title Effect of Basal Testosterone and Dehydroepiandrosterone Sulphate Levels on in Vitro Fertilization Outcome in Normoresponders
title_full Effect of Basal Testosterone and Dehydroepiandrosterone Sulphate Levels on in Vitro Fertilization Outcome in Normoresponders
title_fullStr Effect of Basal Testosterone and Dehydroepiandrosterone Sulphate Levels on in Vitro Fertilization Outcome in Normoresponders
title_full_unstemmed Effect of Basal Testosterone and Dehydroepiandrosterone Sulphate Levels on in Vitro Fertilization Outcome in Normoresponders
title_short Effect of Basal Testosterone and Dehydroepiandrosterone Sulphate Levels on in Vitro Fertilization Outcome in Normoresponders
title_sort effect of basal testosterone and dehydroepiandrosterone sulphate levels on in vitro fertilization outcome in normoresponders
topic Androgen
Normoresponder
In vitro fertilization
url https://gorm.com.tr/index.php/GORM/article/view/212
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