Advances in hydrogel for diagnosis and treatment for Parkinson’s disease

Currently, few symptomatic and palliative care options are available for patients with Parkinson’s disease (PD). Interdisciplinary research in materials engineering and regenerative medicine has stimulated the development of innovative therapeutic strategy for patients with PD. Hydrogels, which are...

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Main Authors: Peining Zhu, Zenghui Zhao, Yufei Gao
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1552586/full
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author Peining Zhu
Peining Zhu
Peining Zhu
Peining Zhu
Zenghui Zhao
Zenghui Zhao
Zenghui Zhao
Zenghui Zhao
Yufei Gao
Yufei Gao
Yufei Gao
Yufei Gao
author_facet Peining Zhu
Peining Zhu
Peining Zhu
Peining Zhu
Zenghui Zhao
Zenghui Zhao
Zenghui Zhao
Zenghui Zhao
Yufei Gao
Yufei Gao
Yufei Gao
Yufei Gao
author_sort Peining Zhu
collection DOAJ
description Currently, few symptomatic and palliative care options are available for patients with Parkinson’s disease (PD). Interdisciplinary research in materials engineering and regenerative medicine has stimulated the development of innovative therapeutic strategy for patients with PD. Hydrogels, which are versatile and accessible to modify, have garnered considerable interests. Hydrogels are a kind of three-dimensional hydrophilic network structure gels that are widely employed in biological materials. Hydrogels are conspicuous in many therapeutic applications, including neuron regeneration, neuroprotection, and diagnosis. This review focuses on the advantageous applications of hydrogel-based biomaterials in diagnosing and treating the patients with PD, including cell culture, disease modeling, carriers for cells, medications and proteins, as well as diagnostic and monitoring biosensors.
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spelling doaj-art-2ec8b03916b349cb8b5c51a0a50f6ce42025-02-12T05:15:07ZengFrontiers Media S.A.Frontiers in Pharmacology1663-98122025-02-011610.3389/fphar.2025.15525861552586Advances in hydrogel for diagnosis and treatment for Parkinson’s diseasePeining Zhu0Peining Zhu1Peining Zhu2Peining Zhu3Zenghui Zhao4Zenghui Zhao5Zenghui Zhao6Zenghui Zhao7Yufei Gao8Yufei Gao9Yufei Gao10Yufei Gao11China-Japan Union Hospital of Jilin University, Changchun, ChinaDepartment of Neurosurgery, China-Japan Union Hospital of Jilin University, Changchun, ChinaJilin Province Neuro-Oncology Engineering Laboratory, Changchun, ChinaJilin Provincial Key Laboratory of Neuro-Oncology, Changchun, ChinaChina-Japan Union Hospital of Jilin University, Changchun, ChinaDepartment of Neurosurgery, China-Japan Union Hospital of Jilin University, Changchun, ChinaJilin Province Neuro-Oncology Engineering Laboratory, Changchun, ChinaJilin Provincial Key Laboratory of Neuro-Oncology, Changchun, ChinaChina-Japan Union Hospital of Jilin University, Changchun, ChinaDepartment of Neurosurgery, China-Japan Union Hospital of Jilin University, Changchun, ChinaJilin Province Neuro-Oncology Engineering Laboratory, Changchun, ChinaJilin Provincial Key Laboratory of Neuro-Oncology, Changchun, ChinaCurrently, few symptomatic and palliative care options are available for patients with Parkinson’s disease (PD). Interdisciplinary research in materials engineering and regenerative medicine has stimulated the development of innovative therapeutic strategy for patients with PD. Hydrogels, which are versatile and accessible to modify, have garnered considerable interests. Hydrogels are a kind of three-dimensional hydrophilic network structure gels that are widely employed in biological materials. Hydrogels are conspicuous in many therapeutic applications, including neuron regeneration, neuroprotection, and diagnosis. This review focuses on the advantageous applications of hydrogel-based biomaterials in diagnosing and treating the patients with PD, including cell culture, disease modeling, carriers for cells, medications and proteins, as well as diagnostic and monitoring biosensors.https://www.frontiersin.org/articles/10.3389/fphar.2025.1552586/fullhydrogelsneural tissue engineeringParkinson’s diseasedelivery systemsbiosensing
spellingShingle Peining Zhu
Peining Zhu
Peining Zhu
Peining Zhu
Zenghui Zhao
Zenghui Zhao
Zenghui Zhao
Zenghui Zhao
Yufei Gao
Yufei Gao
Yufei Gao
Yufei Gao
Advances in hydrogel for diagnosis and treatment for Parkinson’s disease
Frontiers in Pharmacology
hydrogels
neural tissue engineering
Parkinson’s disease
delivery systems
biosensing
title Advances in hydrogel for diagnosis and treatment for Parkinson’s disease
title_full Advances in hydrogel for diagnosis and treatment for Parkinson’s disease
title_fullStr Advances in hydrogel for diagnosis and treatment for Parkinson’s disease
title_full_unstemmed Advances in hydrogel for diagnosis and treatment for Parkinson’s disease
title_short Advances in hydrogel for diagnosis and treatment for Parkinson’s disease
title_sort advances in hydrogel for diagnosis and treatment for parkinson s disease
topic hydrogels
neural tissue engineering
Parkinson’s disease
delivery systems
biosensing
url https://www.frontiersin.org/articles/10.3389/fphar.2025.1552586/full
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