Pregnancy after Cancer Treatment and Pregnancy Associated Cancer: A Single Center Experience with 96 Cases

OBJECTIVE: The objective of our study was to evaluate our experience on pregnancies after cancer treatment and pregnancy-associated cancer. STUDY DESIGN: The clinical records of 96 pregnant women including previously received treatment for cancer and association of cancer with pregnancy who admitt...

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Main Authors: Mert Turğal, Kemal Beksaç, Derman Başaran, Aslıhan Yazıcıoğlu, Özgür Özyüncü, Ömer Aran, M. Sinan Beksaç
Format: Article
Language:English
Published: Medical Network 2015-08-01
Series:Gynecology Obstetrics & Reproductive Medicine
Subjects:
Online Access:https://gorm.com.tr/index.php/GORM/article/view/26
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author Mert Turğal
Kemal Beksaç
Derman Başaran
Aslıhan Yazıcıoğlu
Özgür Özyüncü
Ömer Aran
M. Sinan Beksaç
author_facet Mert Turğal
Kemal Beksaç
Derman Başaran
Aslıhan Yazıcıoğlu
Özgür Özyüncü
Ömer Aran
M. Sinan Beksaç
author_sort Mert Turğal
collection DOAJ
description OBJECTIVE: The objective of our study was to evaluate our experience on pregnancies after cancer treatment and pregnancy-associated cancer. STUDY DESIGN: The clinical records of 96 pregnant women including previously received treatment for cancer and association of cancer with pregnancy who admitted to our department were enrolled between 2002 and 2012. Demographics, pregnancy outcomes, maternal and fetal complications, perinatal outcomes, cancer types and treatments performed were evaluated. RESULTS: The study group was consisting of 96 cases, 59 out of 96 were cancer survivors and 37 were pregnancy-associated cancer patients. Of those thirty seven, 25 were synchronous with the pregnancy and 12 were metachronic. Pregnancies resulted in 77 healthy newborns, 7 abortions and 12 medical terminations. The most common type of cancer was the breast cancer in 25 patients, followed by thyroid, leukemia, osteosarcoma, lymphoma and ovarian cancer. Patients were treated for their cancer with different modalities including surgery, chemotherapy and radiotherapy. We encountered maternal mortality in 8 cases, all occurred after delivery. CONCLUSIONS: Since management of a pregnancy of a cancer survivor and pregnant woman with cancer a hard work, multidisciplinary approach involving gynecologists, pediatricians, oncologists is essential. Interval between cancer and pregnancy and timing of initiation of therapy in cases of pregnancy associated cancer are important issues in the perspective of fetal/neonatal well-being.
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2602-4918
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publishDate 2015-08-01
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series Gynecology Obstetrics & Reproductive Medicine
spelling doaj-art-2ffff0210f2b4b859a62d13c6da905bd2025-02-11T21:25:51ZengMedical NetworkGynecology Obstetrics & Reproductive Medicine1300-47512602-49182015-08-0121221Pregnancy after Cancer Treatment and Pregnancy Associated Cancer: A Single Center Experience with 96 CasesMert Turğal0Kemal Beksaç1Derman Başaran2Aslıhan Yazıcıoğlu3Özgür Özyüncü4Ömer Aran5M. Sinan Beksaç6Department of Obstetrics and Gynecology, Division of Perinatology, Faculty of Medicine, Hacettepe University, AnkaraDepartment of General Surgery, Faculty of Medicine, Hacettepe University, AnkaraDepartment of Obstetrics and Gynecology, Division of Gynecologic Oncology, Faculty of Medicine, Hacettepe University, AnkaraDepartment of Gynecology and Obstetrics, Faculty of Medicine, Hacettepe University, AnkaraDepartment of Obstetrics and Gynecology, Division of Perinatology, Faculty of Medicine, Hacettepe University, AnkaraDepartment of General Surgery, Faculty of Medicine, Hacettepe University, AnkaraDepartment of Obstetrics and Gynecology, Division of Perinatology, Faculty of Medicine, Hacettepe University, Ankara OBJECTIVE: The objective of our study was to evaluate our experience on pregnancies after cancer treatment and pregnancy-associated cancer. STUDY DESIGN: The clinical records of 96 pregnant women including previously received treatment for cancer and association of cancer with pregnancy who admitted to our department were enrolled between 2002 and 2012. Demographics, pregnancy outcomes, maternal and fetal complications, perinatal outcomes, cancer types and treatments performed were evaluated. RESULTS: The study group was consisting of 96 cases, 59 out of 96 were cancer survivors and 37 were pregnancy-associated cancer patients. Of those thirty seven, 25 were synchronous with the pregnancy and 12 were metachronic. Pregnancies resulted in 77 healthy newborns, 7 abortions and 12 medical terminations. The most common type of cancer was the breast cancer in 25 patients, followed by thyroid, leukemia, osteosarcoma, lymphoma and ovarian cancer. Patients were treated for their cancer with different modalities including surgery, chemotherapy and radiotherapy. We encountered maternal mortality in 8 cases, all occurred after delivery. CONCLUSIONS: Since management of a pregnancy of a cancer survivor and pregnant woman with cancer a hard work, multidisciplinary approach involving gynecologists, pediatricians, oncologists is essential. Interval between cancer and pregnancy and timing of initiation of therapy in cases of pregnancy associated cancer are important issues in the perspective of fetal/neonatal well-being. https://gorm.com.tr/index.php/GORM/article/view/26CancerMetachronous tumorSynchronous tumor
spellingShingle Mert Turğal
Kemal Beksaç
Derman Başaran
Aslıhan Yazıcıoğlu
Özgür Özyüncü
Ömer Aran
M. Sinan Beksaç
Pregnancy after Cancer Treatment and Pregnancy Associated Cancer: A Single Center Experience with 96 Cases
Gynecology Obstetrics & Reproductive Medicine
Cancer
Metachronous tumor
Synchronous tumor
title Pregnancy after Cancer Treatment and Pregnancy Associated Cancer: A Single Center Experience with 96 Cases
title_full Pregnancy after Cancer Treatment and Pregnancy Associated Cancer: A Single Center Experience with 96 Cases
title_fullStr Pregnancy after Cancer Treatment and Pregnancy Associated Cancer: A Single Center Experience with 96 Cases
title_full_unstemmed Pregnancy after Cancer Treatment and Pregnancy Associated Cancer: A Single Center Experience with 96 Cases
title_short Pregnancy after Cancer Treatment and Pregnancy Associated Cancer: A Single Center Experience with 96 Cases
title_sort pregnancy after cancer treatment and pregnancy associated cancer a single center experience with 96 cases
topic Cancer
Metachronous tumor
Synchronous tumor
url https://gorm.com.tr/index.php/GORM/article/view/26
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