Carbimazole-induced atypia – A mimicker of malignancy in fine-needle aspiration cytology
A 20-year-old female presented with complaints of thyroid swelling and showed signs and symptoms of thyrotoxicosis and fine-needle aspiration cytology (FNAC) was requested by the surgeon. On examination of FNAC smear, it showed thyroid follicular cells with atypical features like bizarre giant cells...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2023-07-01
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| Series: | Indian Journal of Pathology and Microbiology |
| Subjects: | |
| Online Access: | https://journals.lww.com/10.4103/ijpm.ijpm_513_21 |
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| _version_ | 1825206064579084288 |
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| author | M. Aswin Manikandan B. Shobana S. Marry Lilly J. Thanka |
| author_facet | M. Aswin Manikandan B. Shobana S. Marry Lilly J. Thanka |
| author_sort | M. Aswin Manikandan |
| collection | DOAJ |
| description | A 20-year-old female presented with complaints of thyroid swelling and showed signs and symptoms of thyrotoxicosis and fine-needle aspiration cytology (FNAC) was requested by the surgeon. On examination of FNAC smear, it showed thyroid follicular cells with atypical features like bizarre giant cells, pseudo nuclear inclusions, and mitotic figure. Correlation between clinical history and cytomorphologic features was done and it was reported as atypical changes in thyroid probably due to carbimazole-induced changes. It helped the patient, as radical surgery and its untoward complications were avoided. |
| format | Article |
| id | doaj-art-30d312ff758a41c0b8517f259ef5f330 |
| institution | Kabale University |
| issn | 0377-4929 |
| language | English |
| publishDate | 2023-07-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Pathology and Microbiology |
| spelling | doaj-art-30d312ff758a41c0b8517f259ef5f3302025-02-07T13:34:07ZengWolters Kluwer Medknow PublicationsIndian Journal of Pathology and Microbiology0377-49292023-07-0166360560710.4103/ijpm.ijpm_513_21Carbimazole-induced atypia – A mimicker of malignancy in fine-needle aspiration cytologyM. Aswin ManikandanB. ShobanaS. Marry LillyJ. ThankaA 20-year-old female presented with complaints of thyroid swelling and showed signs and symptoms of thyrotoxicosis and fine-needle aspiration cytology (FNAC) was requested by the surgeon. On examination of FNAC smear, it showed thyroid follicular cells with atypical features like bizarre giant cells, pseudo nuclear inclusions, and mitotic figure. Correlation between clinical history and cytomorphologic features was done and it was reported as atypical changes in thyroid probably due to carbimazole-induced changes. It helped the patient, as radical surgery and its untoward complications were avoided.https://journals.lww.com/10.4103/ijpm.ijpm_513_21carbimazolecomplicationscytological atypia |
| spellingShingle | M. Aswin Manikandan B. Shobana S. Marry Lilly J. Thanka Carbimazole-induced atypia – A mimicker of malignancy in fine-needle aspiration cytology Indian Journal of Pathology and Microbiology carbimazole complications cytological atypia |
| title | Carbimazole-induced atypia – A mimicker of malignancy in fine-needle aspiration cytology |
| title_full | Carbimazole-induced atypia – A mimicker of malignancy in fine-needle aspiration cytology |
| title_fullStr | Carbimazole-induced atypia – A mimicker of malignancy in fine-needle aspiration cytology |
| title_full_unstemmed | Carbimazole-induced atypia – A mimicker of malignancy in fine-needle aspiration cytology |
| title_short | Carbimazole-induced atypia – A mimicker of malignancy in fine-needle aspiration cytology |
| title_sort | carbimazole induced atypia a mimicker of malignancy in fine needle aspiration cytology |
| topic | carbimazole complications cytological atypia |
| url | https://journals.lww.com/10.4103/ijpm.ijpm_513_21 |
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