E3 ubiquitin ligase SYVN1 as a promising therapeutic target for diverse human diseases
Numerous studies conducted in recent years indicate that mammalian E3 ubiquitin ligases serve as key regulators in the maintenance of cellular homeostasis by targeting the ubiquitination of substrate proteins and activating downstream signaling pathways. SYVN1, an E3 ubiquitin ligase, is characteriz...
Saved in:
Main Authors: | Li Zhu, Yong-Ping Liu, Yuan-Wang, Bo-Xuan Sun, Yu-Ting Huang, Ji-Kai Zhao, Jian-Feng Liu, Li-Ming Yu, Hui-Shan Wang |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2025-02-01
|
Series: | Pharmacological Research |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1043661825000283 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
TWIST1 regulates HK2 ubiquitination degradation to promote pancreatic cancer invasion and metastasis
by: Xinxing Wang, et al.
Published: (2025-02-01) -
Platycodin D inhibits tumor proliferation by modulating macrophage polarization through promoting JAK2 ubiquitination
by: Wei Wu, et al.
Published: (2025-02-01) -
Drosophila ubiquitin-specific peptidase 14 stabilizes the PERIOD protein by regulating a ubiquitin ligase SLIMB
by: So Who Kang, et al.
Published: (2025-02-01) -
Mechanisms of ubiquitin-independent proteasomal degradation and their roles in age-related neurodegenerative disease
by: Taylor R. Church, et al.
Published: (2025-02-01) -
The Cul3 ubiquitin ligase engages Insomniac as an adaptor to impact sleep and synaptic homeostasis.
by: Qiuling Li, et al.
Published: (2025-01-01)