The gastric microbiome altered by A4GNT deficiency in mice

The gastric microbiome altered by A4GNT deficiency in mice

BackgroundSelective antimicrobial effects have been found for α1,4-linked N-acetylglucosamine residues at the terminus of O-glycans attached to a core protein of gastric gland mucin. A4gnt encodes α1,4-N-acetylglucosaminyl transferase, which is responsible for the biosynthesis of α1,4-linked N-acety...

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Bibliographic Details
Main Authors: Dawei Gong, Yuqiang Gao, Rui Shi, Xiaona Xu, Mengchao Yu, Shumin Zhang, Lili Wang, Quanjiang Dong
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Microbiology
Subjects:
A4gnt
gastric microbiome
Desulfovibrio
Prevotellamassilia
gastric cancer
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2025.1541800/full
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