Natural products targeting RAS by multiple mechanisms and its therapeutic potential in cancer: An update since 2020
RAS proteins, as pivotal signal transduction molecules, are frequently mutated and hyperactivated in various human cancers, closely associated with tumor cell proliferation, survival, and metastasis. Despite extensive research on RAS targeted therapies, developing effective RAS inhibitors remains a...
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Main Authors: | Yanqing Liu, Jie Chen, Xiang Li, Yu Fan, Cheng Peng, Xiaochun Ye, Yingshuang Wang, Xin Xie |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2025-02-01
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Series: | Pharmacological Research |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1043661825000027 |
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