Preoperative anxiety and its impact on surgical outcomes: A systematic review and meta-analysis
Abstract Background: Preoperative anxiety is a common phenomenon affecting 60–80% of surgical patients, with potential implications for surgical outcomes. Despite its prevalence, there remains a lack of consensus on its precise effects and optimal management strategies. Objective: This meta-anal...
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| Format: | Article |
| Language: | English |
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Cambridge University Press
2025-01-01
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| Series: | Journal of Clinical and Translational Science |
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| Online Access: | https://www.cambridge.org/core/product/identifier/S2059866125000068/type/journal_article |
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| author | Mohamed A. Shebl Eman Toraih Menna Shebl Ahmed Mosaad Tolba Parisa Ahmed Harshdeep Singh Banga Mohab Orz Mahmoud Tammam Keroles Saadalla Mohamed Elsayed Mennatallah Kamal Mohamed Abdulla Ahmed Ibrahim Eldessouky Yousef Tarek Moustafa Omar Ahmed Mohamed Hani Aiash |
| author_facet | Mohamed A. Shebl Eman Toraih Menna Shebl Ahmed Mosaad Tolba Parisa Ahmed Harshdeep Singh Banga Mohab Orz Mahmoud Tammam Keroles Saadalla Mohamed Elsayed Mennatallah Kamal Mohamed Abdulla Ahmed Ibrahim Eldessouky Yousef Tarek Moustafa Omar Ahmed Mohamed Hani Aiash |
| author_sort | Mohamed A. Shebl |
| collection | DOAJ |
| description |
Abstract
Background:
Preoperative anxiety is a common phenomenon affecting 60–80% of surgical patients, with potential implications for surgical outcomes. Despite its prevalence, there remains a lack of consensus on its precise effects and optimal management strategies.
Objective:
This meta-analysis aimed to synthesize current evidence on the impact of preoperative anxiety on various surgical outcomes, including anesthetic and analgesic requirements, delirium, recovery times, and pain.
Methods:
We conducted a comprehensive literature search and meta-analysis of studies examining the relationship between preoperative anxiety and surgical outcomes. Standardized mean differences (SMD), correlation (COR), and odds ratios (OR) with 95% confidence intervals were calculated.
Results:
Our analysis revealed significant associations between preoperative anxiety and increased anesthetic requirements (SMD = 0.67, 95% CI: 0.32–1.01) and analgesic requirements (SMD = 0.89, 95% CI: 0.65–1.12). Preoperative anxiety was associated with postoperative delirium in adults (OR = 1.90, 95% CI: 1.11–3.26), unlike the pediatric population. Preoperative anxiety was associated with prolonged time to reach Modified Aldrete Score of 9 (SMD = 0.79, 95% CI: 0.50–1.07) and extubation time (SMD = 0.89, 95% CI: 0.58–1.21). Preoperative anxiety was positively correlated with propofol consumption (STAI-S COR = 0.35, 95%CI: 0.15–0.55). No significant association between preoperative anxiety and postoperative pain was found.
Conclusions:
This meta-analysis provides evidence for the wide-ranging effects of preoperative anxiety on surgical outcomes. The findings emphasize the need for routine preoperative anxiety screening and the development of targeted interventions. Future research should focus on long-term impacts and the effectiveness of various anxiety management strategies.
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| format | Article |
| id | doaj-art-3384b869adb84837bbf8e2c15937a44c |
| institution | Kabale University |
| issn | 2059-8661 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Cambridge University Press |
| record_format | Article |
| series | Journal of Clinical and Translational Science |
| spelling | doaj-art-3384b869adb84837bbf8e2c15937a44c2025-02-12T05:49:10ZengCambridge University PressJournal of Clinical and Translational Science2059-86612025-01-01910.1017/cts.2025.6Preoperative anxiety and its impact on surgical outcomes: A systematic review and meta-analysisMohamed A. Shebl0https://orcid.org/0009-0009-4657-0272Eman Toraih1Menna Shebl2Ahmed Mosaad Tolba3Parisa Ahmed4Harshdeep Singh Banga5Mohab Orz6Mahmoud Tammam7Keroles Saadalla8Mohamed Elsayed9Mennatallah Kamal10Mohamed Abdulla11Ahmed Ibrahim Eldessouky12Yousef Tarek Moustafa13Omar Ahmed Mohamed14Hani Aiash15Faculty of Medicine, Cairo University, Kasr Al-Ainy, Cairo, EgyptTulane University School of Medicine, New Orleans, LA, USA Faculty of Medicine, Suez Canal University, Ismailia, Egypt Upstate Medical University, Syracuse, USAFaculty of Medicine, Modern University for Technology and Information, Cairo, EgyptFaculty of Medicine, Alexandria University, Alexandria, EgyptVirginia Commonwealth University, Richmond, USAUpstate Medical University, Syracuse, USAFaculty of Medicine, Alexandria University, Alexandria, EgyptFaculty of Medicine, Alexandria University, Alexandria, EgyptFaculty of Medicine, Cairo University, Kasr Al-Ainy, Cairo, EgyptDnipropetrovsk Medical Institute of Conventional and Alternative Medicine, Dnipropetrovsk, UkraineFaculty of Medicine, Suez Canal University, Ismailia, EgyptFaculty of Medicine, Alexandria University, Alexandria, EgyptFaculty of Medicine, Suez Canal University, Ismailia, EgyptFaculty of Medicine, Alexandria University, Alexandria, EgyptFaculty of Medicine, Cairo University, Kasr Al-Ainy, Cairo, EgyptFaculty of Medicine, Suez Canal University, Ismailia, Egypt Upstate Medical University, Syracuse, USA Abstract Background: Preoperative anxiety is a common phenomenon affecting 60–80% of surgical patients, with potential implications for surgical outcomes. Despite its prevalence, there remains a lack of consensus on its precise effects and optimal management strategies. Objective: This meta-analysis aimed to synthesize current evidence on the impact of preoperative anxiety on various surgical outcomes, including anesthetic and analgesic requirements, delirium, recovery times, and pain. Methods: We conducted a comprehensive literature search and meta-analysis of studies examining the relationship between preoperative anxiety and surgical outcomes. Standardized mean differences (SMD), correlation (COR), and odds ratios (OR) with 95% confidence intervals were calculated. Results: Our analysis revealed significant associations between preoperative anxiety and increased anesthetic requirements (SMD = 0.67, 95% CI: 0.32–1.01) and analgesic requirements (SMD = 0.89, 95% CI: 0.65–1.12). Preoperative anxiety was associated with postoperative delirium in adults (OR = 1.90, 95% CI: 1.11–3.26), unlike the pediatric population. Preoperative anxiety was associated with prolonged time to reach Modified Aldrete Score of 9 (SMD = 0.79, 95% CI: 0.50–1.07) and extubation time (SMD = 0.89, 95% CI: 0.58–1.21). Preoperative anxiety was positively correlated with propofol consumption (STAI-S COR = 0.35, 95%CI: 0.15–0.55). No significant association between preoperative anxiety and postoperative pain was found. Conclusions: This meta-analysis provides evidence for the wide-ranging effects of preoperative anxiety on surgical outcomes. The findings emphasize the need for routine preoperative anxiety screening and the development of targeted interventions. Future research should focus on long-term impacts and the effectiveness of various anxiety management strategies. https://www.cambridge.org/core/product/identifier/S2059866125000068/type/journal_articlePreoperative anxietydeliriumSTAImYPASpropofol |
| spellingShingle | Mohamed A. Shebl Eman Toraih Menna Shebl Ahmed Mosaad Tolba Parisa Ahmed Harshdeep Singh Banga Mohab Orz Mahmoud Tammam Keroles Saadalla Mohamed Elsayed Mennatallah Kamal Mohamed Abdulla Ahmed Ibrahim Eldessouky Yousef Tarek Moustafa Omar Ahmed Mohamed Hani Aiash Preoperative anxiety and its impact on surgical outcomes: A systematic review and meta-analysis Journal of Clinical and Translational Science Preoperative anxiety delirium STAI mYPAS propofol |
| title | Preoperative anxiety and its impact on surgical outcomes: A systematic review and meta-analysis |
| title_full | Preoperative anxiety and its impact on surgical outcomes: A systematic review and meta-analysis |
| title_fullStr | Preoperative anxiety and its impact on surgical outcomes: A systematic review and meta-analysis |
| title_full_unstemmed | Preoperative anxiety and its impact on surgical outcomes: A systematic review and meta-analysis |
| title_short | Preoperative anxiety and its impact on surgical outcomes: A systematic review and meta-analysis |
| title_sort | preoperative anxiety and its impact on surgical outcomes a systematic review and meta analysis |
| topic | Preoperative anxiety delirium STAI mYPAS propofol |
| url | https://www.cambridge.org/core/product/identifier/S2059866125000068/type/journal_article |
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