Modern Approaches to <i>H. pylori</i> Eradication Therapy in Adults (Literature Review and Resolution of Experts Council)
Aim: to analyze current approaches to H. pylori eradication therapy in adults and present the materials of Experts Council held on December 9, 2022 in Moscow.General statements. H. pylori infection is the main etiological factor of gastritis, peptic ulcer, and gastric cancer. Eradication of H. pylor...
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Gastro LLC
2023-05-01
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Series: | Российский журнал гастроэнтерологии, гепатологии, колопроктологии |
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Online Access: | https://www.gastro-j.ru/jour/article/view/800 |
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author | V. Т. Ivashkin A. I. Ulyanin I. V. Mayev R. S. Kozlov M. A. Livzan S. R. Abdulkhakov O. P. Alekseyeva S. A. Alekseyenko D. S. Bordin N. N. Dekhnich N. V. Korochyanskaya T. L. Lapina E. A. Poluektova V. I. Simanenkov A. S. Trukhmanov I. B. Khlynov V. V. Tsukanov A. A. Sheptulin |
author_facet | V. Т. Ivashkin A. I. Ulyanin I. V. Mayev R. S. Kozlov M. A. Livzan S. R. Abdulkhakov O. P. Alekseyeva S. A. Alekseyenko D. S. Bordin N. N. Dekhnich N. V. Korochyanskaya T. L. Lapina E. A. Poluektova V. I. Simanenkov A. S. Trukhmanov I. B. Khlynov V. V. Tsukanov A. A. Sheptulin |
author_sort | V. Т. Ivashkin |
collection | DOAJ |
description | Aim: to analyze current approaches to H. pylori eradication therapy in adults and present the materials of Experts Council held on December 9, 2022 in Moscow.General statements. H. pylori infection is the main etiological factor of gastritis, peptic ulcer, and gastric cancer. Eradication of H. pylori is recognized as a necessary measure to reduce the incidence of these diseases. The approaches to selecting an eradication regimen should be optimized to take into account epidemiological trends and achieve better treatment outcomes. The updated Maastricht VI Consensus Report presents the means to overcome the difficulties in selecting an approach to the treatment of H. pylori infection. However, eradication therapy remains challenging due to adverse events (primarily antibiotic-associated diarrhea), poor treatment tolerance and patient compliance. Eradication therapy can be optimized by supplementing treatment regimens with strain-specific probiotics that reduce adverse events, improve patient compliance and eradication rates, such as Saccharomyces boulardii CNCM I-745 strain with established efficacy.Conclusion. The inclusion of certain probiotics in eradication regimens improves treatment tolerance, reduces the risk of adverse events, improves patient compliance and eradication rates. |
format | Article |
id | doaj-art-36c3aad790b84e4e9531e6d5a14c83f6 |
institution | Kabale University |
issn | 1382-4376 2658-6673 |
language | Russian |
publishDate | 2023-05-01 |
publisher | Gastro LLC |
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series | Российский журнал гастроэнтерологии, гепатологии, колопроктологии |
spelling | doaj-art-36c3aad790b84e4e9531e6d5a14c83f62025-02-10T16:14:37ZrusGastro LLCРоссийский журнал гастроэнтерологии, гепатологии, колопроктологии1382-43762658-66732023-05-0132671910.22416/1382-4376-2022-32-6-7-19507Modern Approaches to <i>H. pylori</i> Eradication Therapy in Adults (Literature Review and Resolution of Experts Council)V. Т. Ivashkin0A. I. Ulyanin1I. V. Mayev2R. S. Kozlov3M. A. Livzan4S. R. Abdulkhakov5O. P. Alekseyeva6S. A. Alekseyenko7D. S. Bordin8N. N. Dekhnich9N. V. Korochyanskaya10T. L. Lapina11E. A. Poluektova12V. I. Simanenkov13A. S. Trukhmanov14I. B. Khlynov15V. V. Tsukanov16A. A. Sheptulin17I.M. Sechenov First Moscow State Medical University (Sechenov University)I.M. Sechenov First Moscow State Medical University (Sechenov University)A.I. Yevdokimov Moscow State University of Medicine and DentistrySmolensk State Medical UniversityOmsk State Medical UniversityKazan (Volga Region) Federal University; Kazan State Medical UniversityNizhny Novgorod Regional Clinical Hospital named after N.A. SemashkoFar Eastern State Medical UniversityA.I. Yevdokimov Moscow State University of Medicine and Dentistry; A.S. Loginov Moscow Clinical Scientific Center; Tver State Medical UniversitySmolensk State Medical UniversityKuban State Medical UniversityI.M. Sechenov First Moscow State Medical University (Sechenov University)I.M. Sechenov First Moscow State Medical University (Sechenov University)I.I. Mechnikov North-Western State Medical UniversityI.M. Sechenov First Moscow State Medical University (Sechenov University)Ural State Medical UniversityKrasnoyarsk Science Center of the Siberian Branch of the Russian Academy of Sciences, an autonomous branch of the Research Institute of Medical Problems of the NorthI.M. Sechenov First Moscow State Medical University (Sechenov University)Aim: to analyze current approaches to H. pylori eradication therapy in adults and present the materials of Experts Council held on December 9, 2022 in Moscow.General statements. H. pylori infection is the main etiological factor of gastritis, peptic ulcer, and gastric cancer. Eradication of H. pylori is recognized as a necessary measure to reduce the incidence of these diseases. The approaches to selecting an eradication regimen should be optimized to take into account epidemiological trends and achieve better treatment outcomes. The updated Maastricht VI Consensus Report presents the means to overcome the difficulties in selecting an approach to the treatment of H. pylori infection. However, eradication therapy remains challenging due to adverse events (primarily antibiotic-associated diarrhea), poor treatment tolerance and patient compliance. Eradication therapy can be optimized by supplementing treatment regimens with strain-specific probiotics that reduce adverse events, improve patient compliance and eradication rates, such as Saccharomyces boulardii CNCM I-745 strain with established efficacy.Conclusion. The inclusion of certain probiotics in eradication regimens improves treatment tolerance, reduces the risk of adverse events, improves patient compliance and eradication rates.https://www.gastro-j.ru/jour/article/view/800gastritisgastric canceratrophy<i>h. pylori</i>eradicationcompliancemicrobiomemicrobiotaantibioticsprobiotics<i>saccharomyces boulardii</i> cncm i-745 |
spellingShingle | V. Т. Ivashkin A. I. Ulyanin I. V. Mayev R. S. Kozlov M. A. Livzan S. R. Abdulkhakov O. P. Alekseyeva S. A. Alekseyenko D. S. Bordin N. N. Dekhnich N. V. Korochyanskaya T. L. Lapina E. A. Poluektova V. I. Simanenkov A. S. Trukhmanov I. B. Khlynov V. V. Tsukanov A. A. Sheptulin Modern Approaches to <i>H. pylori</i> Eradication Therapy in Adults (Literature Review and Resolution of Experts Council) Российский журнал гастроэнтерологии, гепатологии, колопроктологии gastritis gastric cancer atrophy <i>h. pylori</i> eradication compliance microbiome microbiota antibiotics probiotics <i>saccharomyces boulardii</i> cncm i-745 |
title | Modern Approaches to <i>H. pylori</i> Eradication Therapy in Adults (Literature Review and Resolution of Experts Council) |
title_full | Modern Approaches to <i>H. pylori</i> Eradication Therapy in Adults (Literature Review and Resolution of Experts Council) |
title_fullStr | Modern Approaches to <i>H. pylori</i> Eradication Therapy in Adults (Literature Review and Resolution of Experts Council) |
title_full_unstemmed | Modern Approaches to <i>H. pylori</i> Eradication Therapy in Adults (Literature Review and Resolution of Experts Council) |
title_short | Modern Approaches to <i>H. pylori</i> Eradication Therapy in Adults (Literature Review and Resolution of Experts Council) |
title_sort | modern approaches to i h pylori i eradication therapy in adults literature review and resolution of experts council |
topic | gastritis gastric cancer atrophy <i>h. pylori</i> eradication compliance microbiome microbiota antibiotics probiotics <i>saccharomyces boulardii</i> cncm i-745 |
url | https://www.gastro-j.ru/jour/article/view/800 |
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