Modern Approaches to <i>H. pylori</i> Eradication Therapy in Adults (Literature Review and Resolution of Experts Council)

Aim: to analyze current approaches to H. pylori eradication therapy in adults and present the materials of Experts Council held on December 9, 2022 in Moscow.General statements. H. pylori infection is the main etiological factor of gastritis, peptic ulcer, and gastric cancer. Eradication of H. pylor...

Full description

Saved in:
Bibliographic Details
Main Authors: V. Т. Ivashkin, A. I. Ulyanin, I. V. Mayev, R. S. Kozlov, M. A. Livzan, S. R. Abdulkhakov, O. P. Alekseyeva, S. A. Alekseyenko, D. S. Bordin, N. N. Dekhnich, N. V. Korochyanskaya, T. L. Lapina, E. A. Poluektova, V. I. Simanenkov, A. S. Trukhmanov, I. B. Khlynov, V. V. Tsukanov, A. A. Sheptulin
Format: Article
Language:Russian
Published: Gastro LLC 2023-05-01
Series:Российский журнал гастроэнтерологии, гепатологии, колопроктологии
Subjects:
Online Access:https://www.gastro-j.ru/jour/article/view/800
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1823860119931191296
author V. Т. Ivashkin
A. I. Ulyanin
I. V. Mayev
R. S. Kozlov
M. A. Livzan
S. R. Abdulkhakov
O. P. Alekseyeva
S. A. Alekseyenko
D. S. Bordin
N. N. Dekhnich
N. V. Korochyanskaya
T. L. Lapina
E. A. Poluektova
V. I. Simanenkov
A. S. Trukhmanov
I. B. Khlynov
V. V. Tsukanov
A. A. Sheptulin
author_facet V. Т. Ivashkin
A. I. Ulyanin
I. V. Mayev
R. S. Kozlov
M. A. Livzan
S. R. Abdulkhakov
O. P. Alekseyeva
S. A. Alekseyenko
D. S. Bordin
N. N. Dekhnich
N. V. Korochyanskaya
T. L. Lapina
E. A. Poluektova
V. I. Simanenkov
A. S. Trukhmanov
I. B. Khlynov
V. V. Tsukanov
A. A. Sheptulin
author_sort V. Т. Ivashkin
collection DOAJ
description Aim: to analyze current approaches to H. pylori eradication therapy in adults and present the materials of Experts Council held on December 9, 2022 in Moscow.General statements. H. pylori infection is the main etiological factor of gastritis, peptic ulcer, and gastric cancer. Eradication of H. pylori is recognized as a necessary measure to reduce the incidence of these diseases. The approaches to selecting an eradication regimen should be optimized to take into account epidemiological trends and achieve better treatment outcomes. The updated Maastricht VI Consensus Report presents the means to overcome the difficulties in selecting an approach to the treatment of H. pylori infection. However, eradication therapy remains challenging due to adverse events (primarily antibiotic-associated diarrhea), poor treatment tolerance and patient compliance. Eradication therapy can be optimized by supplementing treatment regimens with strain-specific probiotics that reduce adverse events, improve patient compliance and eradication rates, such as Saccharomyces boulardii CNCM I-745 strain with established efficacy.Conclusion. The inclusion of certain probiotics in eradication regimens improves treatment tolerance, reduces the risk of adverse events, improves patient compliance and eradication rates.
format Article
id doaj-art-36c3aad790b84e4e9531e6d5a14c83f6
institution Kabale University
issn 1382-4376
2658-6673
language Russian
publishDate 2023-05-01
publisher Gastro LLC
record_format Article
series Российский журнал гастроэнтерологии, гепатологии, колопроктологии
spelling doaj-art-36c3aad790b84e4e9531e6d5a14c83f62025-02-10T16:14:37ZrusGastro LLCРоссийский журнал гастроэнтерологии, гепатологии, колопроктологии1382-43762658-66732023-05-0132671910.22416/1382-4376-2022-32-6-7-19507Modern Approaches to <i>H. pylori</i> Eradication Therapy in Adults (Literature Review and Resolution of Experts Council)V. Т. Ivashkin0A. I. Ulyanin1I. V. Mayev2R. S. Kozlov3M. A. Livzan4S. R. Abdulkhakov5O. P. Alekseyeva6S. A. Alekseyenko7D. S. Bordin8N. N. Dekhnich9N. V. Korochyanskaya10T. L. Lapina11E. A. Poluektova12V. I. Simanenkov13A. S. Trukhmanov14I. B. Khlynov15V. V. Tsukanov16A. A. Sheptulin17I.M. Sechenov First Moscow State Medical University (Sechenov University)I.M. Sechenov First Moscow State Medical University (Sechenov University)A.I. Yevdokimov Moscow State University of Medicine and DentistrySmolensk State Medical UniversityOmsk State Medical UniversityKazan (Volga Region) Federal University; Kazan State Medical UniversityNizhny Novgorod Regional Clinical Hospital named after N.A. SemashkoFar Eastern State Medical UniversityA.I. Yevdokimov Moscow State University of Medicine and Dentistry; A.S. Loginov Moscow Clinical Scientific Center; Tver State Medical UniversitySmolensk State Medical UniversityKuban State Medical UniversityI.M. Sechenov First Moscow State Medical University (Sechenov University)I.M. Sechenov First Moscow State Medical University (Sechenov University)I.I. Mechnikov North-Western State Medical UniversityI.M. Sechenov First Moscow State Medical University (Sechenov University)Ural State Medical UniversityKrasnoyarsk Science Center of the Siberian Branch of the Russian Academy of Sciences, an autonomous branch of the Research Institute of Medical Problems of the NorthI.M. Sechenov First Moscow State Medical University (Sechenov University)Aim: to analyze current approaches to H. pylori eradication therapy in adults and present the materials of Experts Council held on December 9, 2022 in Moscow.General statements. H. pylori infection is the main etiological factor of gastritis, peptic ulcer, and gastric cancer. Eradication of H. pylori is recognized as a necessary measure to reduce the incidence of these diseases. The approaches to selecting an eradication regimen should be optimized to take into account epidemiological trends and achieve better treatment outcomes. The updated Maastricht VI Consensus Report presents the means to overcome the difficulties in selecting an approach to the treatment of H. pylori infection. However, eradication therapy remains challenging due to adverse events (primarily antibiotic-associated diarrhea), poor treatment tolerance and patient compliance. Eradication therapy can be optimized by supplementing treatment regimens with strain-specific probiotics that reduce adverse events, improve patient compliance and eradication rates, such as Saccharomyces boulardii CNCM I-745 strain with established efficacy.Conclusion. The inclusion of certain probiotics in eradication regimens improves treatment tolerance, reduces the risk of adverse events, improves patient compliance and eradication rates.https://www.gastro-j.ru/jour/article/view/800gastritisgastric canceratrophy<i>h. pylori</i>eradicationcompliancemicrobiomemicrobiotaantibioticsprobiotics<i>saccharomyces boulardii</i> cncm i-745
spellingShingle V. Т. Ivashkin
A. I. Ulyanin
I. V. Mayev
R. S. Kozlov
M. A. Livzan
S. R. Abdulkhakov
O. P. Alekseyeva
S. A. Alekseyenko
D. S. Bordin
N. N. Dekhnich
N. V. Korochyanskaya
T. L. Lapina
E. A. Poluektova
V. I. Simanenkov
A. S. Trukhmanov
I. B. Khlynov
V. V. Tsukanov
A. A. Sheptulin
Modern Approaches to <i>H. pylori</i> Eradication Therapy in Adults (Literature Review and Resolution of Experts Council)
Российский журнал гастроэнтерологии, гепатологии, колопроктологии
gastritis
gastric cancer
atrophy
<i>h. pylori</i>
eradication
compliance
microbiome
microbiota
antibiotics
probiotics
<i>saccharomyces boulardii</i> cncm i-745
title Modern Approaches to <i>H. pylori</i> Eradication Therapy in Adults (Literature Review and Resolution of Experts Council)
title_full Modern Approaches to <i>H. pylori</i> Eradication Therapy in Adults (Literature Review and Resolution of Experts Council)
title_fullStr Modern Approaches to <i>H. pylori</i> Eradication Therapy in Adults (Literature Review and Resolution of Experts Council)
title_full_unstemmed Modern Approaches to <i>H. pylori</i> Eradication Therapy in Adults (Literature Review and Resolution of Experts Council)
title_short Modern Approaches to <i>H. pylori</i> Eradication Therapy in Adults (Literature Review and Resolution of Experts Council)
title_sort modern approaches to i h pylori i eradication therapy in adults literature review and resolution of experts council
topic gastritis
gastric cancer
atrophy
<i>h. pylori</i>
eradication
compliance
microbiome
microbiota
antibiotics
probiotics
<i>saccharomyces boulardii</i> cncm i-745
url https://www.gastro-j.ru/jour/article/view/800
work_keys_str_mv AT vtivashkin modernapproachestoihpyloriieradicationtherapyinadultsliteraturereviewandresolutionofexpertscouncil
AT aiulyanin modernapproachestoihpyloriieradicationtherapyinadultsliteraturereviewandresolutionofexpertscouncil
AT ivmayev modernapproachestoihpyloriieradicationtherapyinadultsliteraturereviewandresolutionofexpertscouncil
AT rskozlov modernapproachestoihpyloriieradicationtherapyinadultsliteraturereviewandresolutionofexpertscouncil
AT malivzan modernapproachestoihpyloriieradicationtherapyinadultsliteraturereviewandresolutionofexpertscouncil
AT srabdulkhakov modernapproachestoihpyloriieradicationtherapyinadultsliteraturereviewandresolutionofexpertscouncil
AT opalekseyeva modernapproachestoihpyloriieradicationtherapyinadultsliteraturereviewandresolutionofexpertscouncil
AT saalekseyenko modernapproachestoihpyloriieradicationtherapyinadultsliteraturereviewandresolutionofexpertscouncil
AT dsbordin modernapproachestoihpyloriieradicationtherapyinadultsliteraturereviewandresolutionofexpertscouncil
AT nndekhnich modernapproachestoihpyloriieradicationtherapyinadultsliteraturereviewandresolutionofexpertscouncil
AT nvkorochyanskaya modernapproachestoihpyloriieradicationtherapyinadultsliteraturereviewandresolutionofexpertscouncil
AT tllapina modernapproachestoihpyloriieradicationtherapyinadultsliteraturereviewandresolutionofexpertscouncil
AT eapoluektova modernapproachestoihpyloriieradicationtherapyinadultsliteraturereviewandresolutionofexpertscouncil
AT visimanenkov modernapproachestoihpyloriieradicationtherapyinadultsliteraturereviewandresolutionofexpertscouncil
AT astrukhmanov modernapproachestoihpyloriieradicationtherapyinadultsliteraturereviewandresolutionofexpertscouncil
AT ibkhlynov modernapproachestoihpyloriieradicationtherapyinadultsliteraturereviewandresolutionofexpertscouncil
AT vvtsukanov modernapproachestoihpyloriieradicationtherapyinadultsliteraturereviewandresolutionofexpertscouncil
AT aasheptulin modernapproachestoihpyloriieradicationtherapyinadultsliteraturereviewandresolutionofexpertscouncil