A multiplex method for rapidly identifying viral protease inhibitors

A multiplex method for rapidly identifying viral protease inhibitors

Abstract With current treatments addressing only a fraction of pathogens and new viral threats constantly evolving, there is a critical need to expand our existing therapeutic arsenal. To speed the rate of discovery and better prepare against future threats, we establish a high-throughput platform c...

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Bibliographic Details
Main Authors: Seo Jung Hong, Samuel J Resnick, Sho Iketani, Ji Won Cha, Benjamin Alexander Albert, Christopher T Fazekas, Ching-Wen Chang, Hengrui Liu, Shlomi Dagan, Michael R Abagyan, Pavla Fajtová, Bruce Culbertson, Brooklyn Brace, Eswar R Reddem, Farhad Forouhar, J Fraser Glickman, James M Balkovec, Brent R Stockwell, Lawrence Shapiro, Anthony J O’Donoghue, Yosef Sabo, Joel S Freundlich, David D Ho, Alejandro Chavez
Format: Article
Language:English
Published: Springer Nature 2025-01-01
Series:Molecular Systems Biology
Subjects:
Antiviral
Biosensors
Drug Screening
High-Throughput
Multiplex
Online Access:https://doi.org/10.1038/s44320-024-00082-1
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