A case report of discordant Chikungunya manifestations in a married couple: From acute undifferentiated fever to fatal sepsis with purpura fulminans

Chikungunya virus, an alphavirus transmitted by mosquitoes, causes chikungunya fever, a non-fatal febrile illness characterized by severe arthralgia and rash. We are reporting on two Chikungunya cases who recently returned from the Thailand-Cambodia border. The first case involved a man who presente...

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Main Authors: Ditthawat Pathomchareansukchai, Navin Horthongkham, Pinyo Rattanaumpawan
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:IDCases
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Online Access:http://www.sciencedirect.com/science/article/pii/S221425092500037X
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author Ditthawat Pathomchareansukchai
Navin Horthongkham
Pinyo Rattanaumpawan
author_facet Ditthawat Pathomchareansukchai
Navin Horthongkham
Pinyo Rattanaumpawan
author_sort Ditthawat Pathomchareansukchai
collection DOAJ
description Chikungunya virus, an alphavirus transmitted by mosquitoes, causes chikungunya fever, a non-fatal febrile illness characterized by severe arthralgia and rash. We are reporting on two Chikungunya cases who recently returned from the Thailand-Cambodia border. The first case involved a man who presented with atypical manifestations, including purpura fulminans and multi-organ failure, ultimately leading to death. Conversely, the subsequent case pertains to the spouse of the deceased, who exhibited typical symptoms.
format Article
id doaj-art-383a4777716448e585373a8de9636efb
institution Kabale University
issn 2214-2509
language English
publishDate 2025-01-01
publisher Elsevier
record_format Article
series IDCases
spelling doaj-art-383a4777716448e585373a8de9636efb2025-02-07T04:47:33ZengElsevierIDCases2214-25092025-01-0139e02182A case report of discordant Chikungunya manifestations in a married couple: From acute undifferentiated fever to fatal sepsis with purpura fulminansDitthawat Pathomchareansukchai0Navin Horthongkham1Pinyo Rattanaumpawan2Division of Infectious Diseases and Tropical Medicine, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, ThailandDepartment of Microbiology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, ThailandDivision of Infectious Diseases and Tropical Medicine, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand; Correspondence to: 2 Wanglang Road, Bangkoknoi, Bangkok 10700, Thailand.Chikungunya virus, an alphavirus transmitted by mosquitoes, causes chikungunya fever, a non-fatal febrile illness characterized by severe arthralgia and rash. We are reporting on two Chikungunya cases who recently returned from the Thailand-Cambodia border. The first case involved a man who presented with atypical manifestations, including purpura fulminans and multi-organ failure, ultimately leading to death. Conversely, the subsequent case pertains to the spouse of the deceased, who exhibited typical symptoms.http://www.sciencedirect.com/science/article/pii/S221425092500037XAcute undifferentiated feverChikungunyaPurpura fulminansSeptic shock
spellingShingle Ditthawat Pathomchareansukchai
Navin Horthongkham
Pinyo Rattanaumpawan
A case report of discordant Chikungunya manifestations in a married couple: From acute undifferentiated fever to fatal sepsis with purpura fulminans
IDCases
Acute undifferentiated fever
Chikungunya
Purpura fulminans
Septic shock
title A case report of discordant Chikungunya manifestations in a married couple: From acute undifferentiated fever to fatal sepsis with purpura fulminans
title_full A case report of discordant Chikungunya manifestations in a married couple: From acute undifferentiated fever to fatal sepsis with purpura fulminans
title_fullStr A case report of discordant Chikungunya manifestations in a married couple: From acute undifferentiated fever to fatal sepsis with purpura fulminans
title_full_unstemmed A case report of discordant Chikungunya manifestations in a married couple: From acute undifferentiated fever to fatal sepsis with purpura fulminans
title_short A case report of discordant Chikungunya manifestations in a married couple: From acute undifferentiated fever to fatal sepsis with purpura fulminans
title_sort case report of discordant chikungunya manifestations in a married couple from acute undifferentiated fever to fatal sepsis with purpura fulminans
topic Acute undifferentiated fever
Chikungunya
Purpura fulminans
Septic shock
url http://www.sciencedirect.com/science/article/pii/S221425092500037X
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