Efficacy of Group O Washed Red Blood Cell Transfusion on Vital Signs and Hematologic Stability in Trauma Patients With Different Blood Types
Xian-Juan Gou,1 Lin-Fei Li,1 Xiao-Li He,1 Xi Chen,2 An-Yong Yu,1 Wei-Yan Tian1 1Department of Emergency, Affiliated Hospital of Zunyi Medical University, Zunyi City, Guizhou Province, 563000, People’s Republic of China; 2School of Nursing, Zunyi Medical University, Zunyi City, Guizhou Province, 5630...
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Dove Medical Press
2025-02-01
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| author | Gou XJ Li LF He XL Chen X Yu AY Tian WY |
| author_facet | Gou XJ Li LF He XL Chen X Yu AY Tian WY |
| author_sort | Gou XJ |
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| description | Xian-Juan Gou,1 Lin-Fei Li,1 Xiao-Li He,1 Xi Chen,2 An-Yong Yu,1 Wei-Yan Tian1 1Department of Emergency, Affiliated Hospital of Zunyi Medical University, Zunyi City, Guizhou Province, 563000, People’s Republic of China; 2School of Nursing, Zunyi Medical University, Zunyi City, Guizhou Province, 563000, People’s Republic of ChinaCorrespondence: Wei-Yan Tian, Department of Emergency, Affiliated Hospital of Zunyi Medical University, Zunyi City, Guizhou Province, 563000, People’s Republic of China, Tel +86 19184321912, Email [email protected]: To comprehensively assess the impact of emergency transfusion of group O washed red blood cells on the vital signs and hematological parameters of patients with severe trauma and to analyze the differential responses among different blood types, thereby providing valuable evidence for optimizing transfusion strategies.Methods: A retrospective analysis was conducted on the clinical data of patients with severe trauma who underwent emergency transfusion in the hospital’s emergency department from April 2023 to March 2024. Changes in blood biochemical indexes and vital signs before and after transfusion were compared, and adverse transfusion reactions were monitored.Results: A total of 65 patients were included in the study, and no adverse transfusion reactions were observed. The shock index (SI) score was 1.07 ± 0.28. Significant changes were noted in platelet count (PLT), activated partial thromboplastin time (APTT), and C-reactive protein (CRP) following transfusion (P < 0.05). Both blood pressure and SI enhanced significantly after transfusion (P < 0.05), although no significant change in heart rate (HR) was detected (P = 0.87). Patients with blood group A experienced a significant reduction in HR post-transfusion. In patients with blood groups AB or O, systolic blood pressure (SBP) significantly increased, and SI significantly decreased. Additionally, patients with blood group O revealed a significant rise in diastolic blood pressure (DBP) post-transfusion, with the differences being statistically significant (P < 0.05).Conclusion: Timely and effective transfusion of group O washed red blood cells is crucial for stabilizing the vital signs of patients with severe trauma. This approach is not only safe but also feasible, with blood type influencing the response to transfusion. Larger, multi-center studies are warranted to further validate these findings and enhance the generalizability.Keywords: blood group, group O washed red blood cells, safety, severe trauma, shock index |
| format | Article |
| id | doaj-art-392674b031d44dc3918a858c47cbac31 |
| institution | Kabale University |
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| language | English |
| publishDate | 2025-02-01 |
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| series | Journal of Multidisciplinary Healthcare |
| spelling | doaj-art-392674b031d44dc3918a858c47cbac312025-02-11T17:30:56ZengDove Medical PressJournal of Multidisciplinary Healthcare1178-23902025-02-01Volume 18711719100044Efficacy of Group O Washed Red Blood Cell Transfusion on Vital Signs and Hematologic Stability in Trauma Patients With Different Blood TypesGou XJLi LFHe XLChen XYu AYTian WYXian-Juan Gou,1 Lin-Fei Li,1 Xiao-Li He,1 Xi Chen,2 An-Yong Yu,1 Wei-Yan Tian1 1Department of Emergency, Affiliated Hospital of Zunyi Medical University, Zunyi City, Guizhou Province, 563000, People’s Republic of China; 2School of Nursing, Zunyi Medical University, Zunyi City, Guizhou Province, 563000, People’s Republic of ChinaCorrespondence: Wei-Yan Tian, Department of Emergency, Affiliated Hospital of Zunyi Medical University, Zunyi City, Guizhou Province, 563000, People’s Republic of China, Tel +86 19184321912, Email [email protected]: To comprehensively assess the impact of emergency transfusion of group O washed red blood cells on the vital signs and hematological parameters of patients with severe trauma and to analyze the differential responses among different blood types, thereby providing valuable evidence for optimizing transfusion strategies.Methods: A retrospective analysis was conducted on the clinical data of patients with severe trauma who underwent emergency transfusion in the hospital’s emergency department from April 2023 to March 2024. Changes in blood biochemical indexes and vital signs before and after transfusion were compared, and adverse transfusion reactions were monitored.Results: A total of 65 patients were included in the study, and no adverse transfusion reactions were observed. The shock index (SI) score was 1.07 ± 0.28. Significant changes were noted in platelet count (PLT), activated partial thromboplastin time (APTT), and C-reactive protein (CRP) following transfusion (P < 0.05). Both blood pressure and SI enhanced significantly after transfusion (P < 0.05), although no significant change in heart rate (HR) was detected (P = 0.87). Patients with blood group A experienced a significant reduction in HR post-transfusion. In patients with blood groups AB or O, systolic blood pressure (SBP) significantly increased, and SI significantly decreased. Additionally, patients with blood group O revealed a significant rise in diastolic blood pressure (DBP) post-transfusion, with the differences being statistically significant (P < 0.05).Conclusion: Timely and effective transfusion of group O washed red blood cells is crucial for stabilizing the vital signs of patients with severe trauma. This approach is not only safe but also feasible, with blood type influencing the response to transfusion. Larger, multi-center studies are warranted to further validate these findings and enhance the generalizability.Keywords: blood group, group O washed red blood cells, safety, severe trauma, shock indexhttps://www.dovepress.com/efficacy-of-group-o-washed-red-blood-cell-transfusion-on-vital-signs-a-peer-reviewed-fulltext-article-JMDHblood groupgroup o washed red blood cellssafetysevere traumashock index |
| spellingShingle | Gou XJ Li LF He XL Chen X Yu AY Tian WY Efficacy of Group O Washed Red Blood Cell Transfusion on Vital Signs and Hematologic Stability in Trauma Patients With Different Blood Types Journal of Multidisciplinary Healthcare blood group group o washed red blood cells safety severe trauma shock index |
| title | Efficacy of Group O Washed Red Blood Cell Transfusion on Vital Signs and Hematologic Stability in Trauma Patients With Different Blood Types |
| title_full | Efficacy of Group O Washed Red Blood Cell Transfusion on Vital Signs and Hematologic Stability in Trauma Patients With Different Blood Types |
| title_fullStr | Efficacy of Group O Washed Red Blood Cell Transfusion on Vital Signs and Hematologic Stability in Trauma Patients With Different Blood Types |
| title_full_unstemmed | Efficacy of Group O Washed Red Blood Cell Transfusion on Vital Signs and Hematologic Stability in Trauma Patients With Different Blood Types |
| title_short | Efficacy of Group O Washed Red Blood Cell Transfusion on Vital Signs and Hematologic Stability in Trauma Patients With Different Blood Types |
| title_sort | efficacy of group o washed red blood cell transfusion on vital signs and hematologic stability in trauma patients with different blood types |
| topic | blood group group o washed red blood cells safety severe trauma shock index |
| url | https://www.dovepress.com/efficacy-of-group-o-washed-red-blood-cell-transfusion-on-vital-signs-a-peer-reviewed-fulltext-article-JMDH |
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