Crystal storing histiocytosis forming a mass lesion in temporal lobe
Crystal storing histiocytosis is a disorder characterized by local or diffuse infiltration of histiocytes containing crystalline inclusions. This entity has been reported in several organs, however the involvement of the central nervous system (CNS) is extremely rare and to date only 7 cases of crys...
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Format: | Article |
Language: | English |
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Wolters Kluwer Medknow Publications
2023-07-01
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Series: | Indian Journal of Pathology and Microbiology |
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Online Access: | https://journals.lww.com/10.4103/ijpm.ijpm_373_21 |
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author | Mine Özşen Şahsine Tolunay Hasan Kocaeli Müfit Parlak |
author_facet | Mine Özşen Şahsine Tolunay Hasan Kocaeli Müfit Parlak |
author_sort | Mine Özşen |
collection | DOAJ |
description | Crystal storing histiocytosis is a disorder characterized by local or diffuse infiltration of histiocytes containing crystalline inclusions. This entity has been reported in several organs, however the involvement of the central nervous system (CNS) is extremely rare and to date only 7 cases of crystal storing histiocytosis (CSH) of CNS have been reported in the English literature. More than 90% patients with CSH had an underlying lymphoproliferative or plasma cell disorders, especially multiple myeloma, lymphoplasmacytic lymphoma or monoclonal gammopathy. Radiologically and intraoperatively, CSH may mimic an infectious process or neoplasm, hence its histopathological confirmation is important to facilitate appropriate treatment. In this report, we describe an additional case of crystal storing histiocytosis in a 48 year old female who presented with a mass lesion in the right temporal lobe of the cerebrum. |
format | Article |
id | doaj-art-3c010f7affd74f72970d01fd3afc1854 |
institution | Kabale University |
issn | 0377-4929 |
language | English |
publishDate | 2023-07-01 |
publisher | Wolters Kluwer Medknow Publications |
record_format | Article |
series | Indian Journal of Pathology and Microbiology |
spelling | doaj-art-3c010f7affd74f72970d01fd3afc18542025-02-07T13:38:25ZengWolters Kluwer Medknow PublicationsIndian Journal of Pathology and Microbiology0377-49292023-07-0166365565810.4103/ijpm.ijpm_373_21Crystal storing histiocytosis forming a mass lesion in temporal lobeMine ÖzşenŞahsine TolunayHasan KocaeliMüfit ParlakCrystal storing histiocytosis is a disorder characterized by local or diffuse infiltration of histiocytes containing crystalline inclusions. This entity has been reported in several organs, however the involvement of the central nervous system (CNS) is extremely rare and to date only 7 cases of crystal storing histiocytosis (CSH) of CNS have been reported in the English literature. More than 90% patients with CSH had an underlying lymphoproliferative or plasma cell disorders, especially multiple myeloma, lymphoplasmacytic lymphoma or monoclonal gammopathy. Radiologically and intraoperatively, CSH may mimic an infectious process or neoplasm, hence its histopathological confirmation is important to facilitate appropriate treatment. In this report, we describe an additional case of crystal storing histiocytosis in a 48 year old female who presented with a mass lesion in the right temporal lobe of the cerebrum.https://journals.lww.com/10.4103/ijpm.ijpm_373_21central nervous systemcrystal-storing histiocytosislymphomamultiple myeloma |
spellingShingle | Mine Özşen Şahsine Tolunay Hasan Kocaeli Müfit Parlak Crystal storing histiocytosis forming a mass lesion in temporal lobe Indian Journal of Pathology and Microbiology central nervous system crystal-storing histiocytosis lymphoma multiple myeloma |
title | Crystal storing histiocytosis forming a mass lesion in temporal lobe |
title_full | Crystal storing histiocytosis forming a mass lesion in temporal lobe |
title_fullStr | Crystal storing histiocytosis forming a mass lesion in temporal lobe |
title_full_unstemmed | Crystal storing histiocytosis forming a mass lesion in temporal lobe |
title_short | Crystal storing histiocytosis forming a mass lesion in temporal lobe |
title_sort | crystal storing histiocytosis forming a mass lesion in temporal lobe |
topic | central nervous system crystal-storing histiocytosis lymphoma multiple myeloma |
url | https://journals.lww.com/10.4103/ijpm.ijpm_373_21 |
work_keys_str_mv | AT mineozsen crystalstoringhistiocytosisformingamasslesionintemporallobe AT sahsinetolunay crystalstoringhistiocytosisformingamasslesionintemporallobe AT hasankocaeli crystalstoringhistiocytosisformingamasslesionintemporallobe AT mufitparlak crystalstoringhistiocytosisformingamasslesionintemporallobe |