Crystal storing histiocytosis forming a mass lesion in temporal lobe

Crystal storing histiocytosis is a disorder characterized by local or diffuse infiltration of histiocytes containing crystalline inclusions. This entity has been reported in several organs, however the involvement of the central nervous system (CNS) is extremely rare and to date only 7 cases of crys...

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Main Authors: Mine Özşen, Şahsine Tolunay, Hasan Kocaeli, Müfit Parlak
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2023-07-01
Series:Indian Journal of Pathology and Microbiology
Subjects:
Online Access:https://journals.lww.com/10.4103/ijpm.ijpm_373_21
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author Mine Özşen
Şahsine Tolunay
Hasan Kocaeli
Müfit Parlak
author_facet Mine Özşen
Şahsine Tolunay
Hasan Kocaeli
Müfit Parlak
author_sort Mine Özşen
collection DOAJ
description Crystal storing histiocytosis is a disorder characterized by local or diffuse infiltration of histiocytes containing crystalline inclusions. This entity has been reported in several organs, however the involvement of the central nervous system (CNS) is extremely rare and to date only 7 cases of crystal storing histiocytosis (CSH) of CNS have been reported in the English literature. More than 90% patients with CSH had an underlying lymphoproliferative or plasma cell disorders, especially multiple myeloma, lymphoplasmacytic lymphoma or monoclonal gammopathy. Radiologically and intraoperatively, CSH may mimic an infectious process or neoplasm, hence its histopathological confirmation is important to facilitate appropriate treatment. In this report, we describe an additional case of crystal storing histiocytosis in a 48 year old female who presented with a mass lesion in the right temporal lobe of the cerebrum.
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institution Kabale University
issn 0377-4929
language English
publishDate 2023-07-01
publisher Wolters Kluwer Medknow Publications
record_format Article
series Indian Journal of Pathology and Microbiology
spelling doaj-art-3c010f7affd74f72970d01fd3afc18542025-02-07T13:38:25ZengWolters Kluwer Medknow PublicationsIndian Journal of Pathology and Microbiology0377-49292023-07-0166365565810.4103/ijpm.ijpm_373_21Crystal storing histiocytosis forming a mass lesion in temporal lobeMine ÖzşenŞahsine TolunayHasan KocaeliMüfit ParlakCrystal storing histiocytosis is a disorder characterized by local or diffuse infiltration of histiocytes containing crystalline inclusions. This entity has been reported in several organs, however the involvement of the central nervous system (CNS) is extremely rare and to date only 7 cases of crystal storing histiocytosis (CSH) of CNS have been reported in the English literature. More than 90% patients with CSH had an underlying lymphoproliferative or plasma cell disorders, especially multiple myeloma, lymphoplasmacytic lymphoma or monoclonal gammopathy. Radiologically and intraoperatively, CSH may mimic an infectious process or neoplasm, hence its histopathological confirmation is important to facilitate appropriate treatment. In this report, we describe an additional case of crystal storing histiocytosis in a 48 year old female who presented with a mass lesion in the right temporal lobe of the cerebrum.https://journals.lww.com/10.4103/ijpm.ijpm_373_21central nervous systemcrystal-storing histiocytosislymphomamultiple myeloma
spellingShingle Mine Özşen
Şahsine Tolunay
Hasan Kocaeli
Müfit Parlak
Crystal storing histiocytosis forming a mass lesion in temporal lobe
Indian Journal of Pathology and Microbiology
central nervous system
crystal-storing histiocytosis
lymphoma
multiple myeloma
title Crystal storing histiocytosis forming a mass lesion in temporal lobe
title_full Crystal storing histiocytosis forming a mass lesion in temporal lobe
title_fullStr Crystal storing histiocytosis forming a mass lesion in temporal lobe
title_full_unstemmed Crystal storing histiocytosis forming a mass lesion in temporal lobe
title_short Crystal storing histiocytosis forming a mass lesion in temporal lobe
title_sort crystal storing histiocytosis forming a mass lesion in temporal lobe
topic central nervous system
crystal-storing histiocytosis
lymphoma
multiple myeloma
url https://journals.lww.com/10.4103/ijpm.ijpm_373_21
work_keys_str_mv AT mineozsen crystalstoringhistiocytosisformingamasslesionintemporallobe
AT sahsinetolunay crystalstoringhistiocytosisformingamasslesionintemporallobe
AT hasankocaeli crystalstoringhistiocytosisformingamasslesionintemporallobe
AT mufitparlak crystalstoringhistiocytosisformingamasslesionintemporallobe