Diagnosis and Treatment of Peptic Ulcer in Adults (Clinical Guidelines of the Russian Gastroenterological Association, Russian Society of Colorectal Surgeons and the Russian Endoscopic Society)

Aim. These clinical recommendations present up-to-date methods for the diagnosis and treatment of peptic ulcer. The recommendations are intended for gastroenterologists and general practitioners.General provisions. Peptic ulcer (PU) represents a chronic relapsing disease occurring with alternating p...

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Main Authors: V. T. Ivashkin, I. V. Maev, P. V. Tsar’kov, M. P. Korolev, D. N. Andreev, E. K. Baranskaya, S. G. Burkov, A. A. Derinov, S. K. Efetov, T. L. Lapina, P. V. Pavlov, S. S. Pirogov, A. V. Tkachev, A. S. Trukhmanov, E. D. Fedorov, A. A. Sheptulin
Format: Article
Language:Russian
Published: Gastro LLC 2020-04-01
Series:Российский журнал гастроэнтерологии, гепатологии, колопроктологии
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Online Access:https://www.gastro-j.ru/jour/article/view/465
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author V. T. Ivashkin
I. V. Maev
P. V. Tsar’kov
M. P. Korolev
D. N. Andreev
E. K. Baranskaya
S. G. Burkov
A. A. Derinov
S. K. Efetov
T. L. Lapina
P. V. Pavlov
S. S. Pirogov
A. V. Tkachev
A. S. Trukhmanov
E. D. Fedorov
A. A. Sheptulin
author_facet V. T. Ivashkin
I. V. Maev
P. V. Tsar’kov
M. P. Korolev
D. N. Andreev
E. K. Baranskaya
S. G. Burkov
A. A. Derinov
S. K. Efetov
T. L. Lapina
P. V. Pavlov
S. S. Pirogov
A. V. Tkachev
A. S. Trukhmanov
E. D. Fedorov
A. A. Sheptulin
author_sort V. T. Ivashkin
collection DOAJ
description Aim. These clinical recommendations present up-to-date methods for the diagnosis and treatment of peptic ulcer. The recommendations are intended for gastroenterologists and general practitioners.General provisions. Peptic ulcer (PU) represents a chronic relapsing disease occurring with alternating periods of exacerbation and remission. The main manifestation of the disease is the formation of a defect (ulcer) in the wall of the stomach and duodenum. Most cases of peptic ulcer are pathogenetically associated with the infection of H. pylori. PU can be an independent disease or represent symptomatic ulcers of the stomach and duodenum (medicinal, as a result of stress or endocrine pathologies, associated with chronic diseases of internal organs). In the absence of contraindications, esophagogastroduodenoscopy is recommended for all patients with suspected ulcer with the purpose of confirming the diagnosis. In order to determine indications for eradication therapy, all ulcer patients should be tested for the presence of H. pylori using a 13C-breath test or a stool antigen test. In the case of simultaneous endoscopy, rapid urease test can be used. For the prevention of subsequent relapses of ulcer, all PU patients with confirmed H. pylori should undergo eradication therapy. In addition, in order to achieve ulcer healing, 4–6 week antisecretory therapy with proton pump inhibitors is recommended. Clinical recommendations contain criteria for assessing the quality of medical care, an algorithm of the doctor’s actions, as well as information for patients.Conclusions. These clinical recommendations present modern ideas about the etiology and pathogenesis of peptic ulcer disease, its clinical manifestations, methods of laboratory and instrumental diagnostics and basic approaches to conservative and surgical treatment.
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spelling doaj-art-3db884f915e24b4f8f77adda6d7808462025-02-10T16:14:36ZrusGastro LLCРоссийский журнал гастроэнтерологии, гепатологии, колопроктологии1382-43762658-66732020-04-01301497010.22416/1382-4376-2020-30-1-49-70357Diagnosis and Treatment of Peptic Ulcer in Adults (Clinical Guidelines of the Russian Gastroenterological Association, Russian Society of Colorectal Surgeons and the Russian Endoscopic Society)V. T. Ivashkin0I. V. Maev1P. V. Tsar’kov2M. P. Korolev3D. N. Andreev4E. K. Baranskaya5S. G. Burkov6A. A. Derinov7S. K. Efetov8T. L. Lapina9P. V. Pavlov10S. S. Pirogov11A. V. Tkachev12A. S. Trukhmanov13E. D. Fedorov14A. A. Sheptulin15I.M. Sechenov First Moscow State Medical UniversityA.I. Yevdokimov Moscow State University of Medicine and DentistryI.M. Sechenov First Moscow State Medical UniversitySt. Petersburg State Paediatric Medical UniversityA.I. Yevdokimov Moscow State University of Medicine and DentistryI.M. Sechenov First Moscow State Medical UniversityPolyclinic No. 3 of the Administrative Department of the President of the Russian FederationI.M. Sechenov First Moscow State Medical UniversityI.M. Sechenov First Moscow State Medical UniversityI.M. Sechenov First Moscow State Medical UniversityI.M. Sechenov First Moscow State Medical UniversityP.A. Gertsen National Medical Research Centre for Radiology, branch of the Moscow Research Institute of OncologyRostov State Medical UniversityI.M. Sechenov First Moscow State Medical UniversityPirogov National Research UniversityI.M. Sechenov First Moscow State Medical UniversityAim. These clinical recommendations present up-to-date methods for the diagnosis and treatment of peptic ulcer. The recommendations are intended for gastroenterologists and general practitioners.General provisions. Peptic ulcer (PU) represents a chronic relapsing disease occurring with alternating periods of exacerbation and remission. The main manifestation of the disease is the formation of a defect (ulcer) in the wall of the stomach and duodenum. Most cases of peptic ulcer are pathogenetically associated with the infection of H. pylori. PU can be an independent disease or represent symptomatic ulcers of the stomach and duodenum (medicinal, as a result of stress or endocrine pathologies, associated with chronic diseases of internal organs). In the absence of contraindications, esophagogastroduodenoscopy is recommended for all patients with suspected ulcer with the purpose of confirming the diagnosis. In order to determine indications for eradication therapy, all ulcer patients should be tested for the presence of H. pylori using a 13C-breath test or a stool antigen test. In the case of simultaneous endoscopy, rapid urease test can be used. For the prevention of subsequent relapses of ulcer, all PU patients with confirmed H. pylori should undergo eradication therapy. In addition, in order to achieve ulcer healing, 4–6 week antisecretory therapy with proton pump inhibitors is recommended. Clinical recommendations contain criteria for assessing the quality of medical care, an algorithm of the doctor’s actions, as well as information for patients.Conclusions. These clinical recommendations present modern ideas about the etiology and pathogenesis of peptic ulcer disease, its clinical manifestations, methods of laboratory and instrumental diagnostics and basic approaches to conservative and surgical treatment.https://www.gastro-j.ru/jour/article/view/465peptic ulcerpeptic ulcer bleedingperforationstenosish. pylorih. pylori eradication therapyproton pump inhibitors
spellingShingle V. T. Ivashkin
I. V. Maev
P. V. Tsar’kov
M. P. Korolev
D. N. Andreev
E. K. Baranskaya
S. G. Burkov
A. A. Derinov
S. K. Efetov
T. L. Lapina
P. V. Pavlov
S. S. Pirogov
A. V. Tkachev
A. S. Trukhmanov
E. D. Fedorov
A. A. Sheptulin
Diagnosis and Treatment of Peptic Ulcer in Adults (Clinical Guidelines of the Russian Gastroenterological Association, Russian Society of Colorectal Surgeons and the Russian Endoscopic Society)
Российский журнал гастроэнтерологии, гепатологии, колопроктологии
peptic ulcer
peptic ulcer bleeding
perforation
stenosis
h. pylori
h. pylori eradication therapy
proton pump inhibitors
title Diagnosis and Treatment of Peptic Ulcer in Adults (Clinical Guidelines of the Russian Gastroenterological Association, Russian Society of Colorectal Surgeons and the Russian Endoscopic Society)
title_full Diagnosis and Treatment of Peptic Ulcer in Adults (Clinical Guidelines of the Russian Gastroenterological Association, Russian Society of Colorectal Surgeons and the Russian Endoscopic Society)
title_fullStr Diagnosis and Treatment of Peptic Ulcer in Adults (Clinical Guidelines of the Russian Gastroenterological Association, Russian Society of Colorectal Surgeons and the Russian Endoscopic Society)
title_full_unstemmed Diagnosis and Treatment of Peptic Ulcer in Adults (Clinical Guidelines of the Russian Gastroenterological Association, Russian Society of Colorectal Surgeons and the Russian Endoscopic Society)
title_short Diagnosis and Treatment of Peptic Ulcer in Adults (Clinical Guidelines of the Russian Gastroenterological Association, Russian Society of Colorectal Surgeons and the Russian Endoscopic Society)
title_sort diagnosis and treatment of peptic ulcer in adults clinical guidelines of the russian gastroenterological association russian society of colorectal surgeons and the russian endoscopic society
topic peptic ulcer
peptic ulcer bleeding
perforation
stenosis
h. pylori
h. pylori eradication therapy
proton pump inhibitors
url https://www.gastro-j.ru/jour/article/view/465
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