Comparison of the effects of lidocaine and articaine used for buccal infiltration and supplemental palatinal infiltration anesthesia in maxillary molars with irreversible pulpitis: a prospective randomized study

Abstract Objectives The aim of the study was to compare the efficiency of buccal infiltration versus combination of buccal and palatal infiltration to anesthetize maxillary molars with symptomaticirreversible pulpitis, wither lidocaine or articaine are used. Material-methods This randomized clinical...

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Main Authors: Duygu Kolay, Damla Kırıcı
Format: Article
Language:English
Published: BMC 2025-02-01
Series:BMC Oral Health
Subjects:
Online Access:https://doi.org/10.1186/s12903-025-05552-y
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author Duygu Kolay
Damla Kırıcı
author_facet Duygu Kolay
Damla Kırıcı
author_sort Duygu Kolay
collection DOAJ
description Abstract Objectives The aim of the study was to compare the efficiency of buccal infiltration versus combination of buccal and palatal infiltration to anesthetize maxillary molars with symptomaticirreversible pulpitis, wither lidocaine or articaine are used. Material-methods This randomized clinical study was conducted on 80 patients with symptomatic irreversible pulpitis of the maxillary first and second molars. Eighty patients were divided into 4 groups (n = 20). (1) group buccal infiltration with 1.2 ml 4% articaine containing 1:100,000 epinephrine, (2) group buccal infiltration with 1.2 ml 2% lidocaine containing 80,000 epinephrine, (3) group buccal infiltration with 1.2 ml 4% articaine containing 1:100,000 epinephrine and palatinal infiltration with 0.5 ml 4% articaine containing 1:100,000 epinephrine, 4.group buccal infiltration with 1.2 ml 2% lidocaine containing 80.000 epinephrine and palatinal infiltration with 0.5 ml lidocaine containing 80.000 epinephrine. The pain intensity was measured by the Heft-Parker visual analog scale (VAS) before injection, during access cavity preparation and access palatal canal. The data were analyzed by the chi-square and The Kruskal–Wallis tests. Results Within the results of the study, no statistically significant difference was found between 4% articaine containing 1:100,000 epinephrine and 2% lidocaine containing 1:80,000 epinephrine in terms of anesthesia effectiveness (p > 0.05). When palatal infiltration anesthesia was applied in addition to buccal infiltration, the pain during entry into the palatal canals was significantly reduced compared to buccal infiltration anesthesia alone (p < 0.05). Conclusions According to the results of this study, it may be recommended to use palatal infiltration anesthesia in addition to buccal infiltration anesthesia, independent of the anesthetic solution, for an effective pulpal anesthesia in maxillary molars with irreversible pulpitis. Clinical trial registration Registration number is “NCT06342869” and date of registration is 2024-04-02.Retrospectively registered.
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spelling doaj-art-4332ee0f7e1049af85622f0107d2d5412025-02-09T12:57:22ZengBMCBMC Oral Health1472-68312025-02-012511910.1186/s12903-025-05552-yComparison of the effects of lidocaine and articaine used for buccal infiltration and supplemental palatinal infiltration anesthesia in maxillary molars with irreversible pulpitis: a prospective randomized studyDuygu Kolay0Damla Kırıcı1Dentistry of Faculty, Department of Endodontics, Akdeniz UniversityDentistry of Faculty, Department of Endodontics, Akdeniz UniversityAbstract Objectives The aim of the study was to compare the efficiency of buccal infiltration versus combination of buccal and palatal infiltration to anesthetize maxillary molars with symptomaticirreversible pulpitis, wither lidocaine or articaine are used. Material-methods This randomized clinical study was conducted on 80 patients with symptomatic irreversible pulpitis of the maxillary first and second molars. Eighty patients were divided into 4 groups (n = 20). (1) group buccal infiltration with 1.2 ml 4% articaine containing 1:100,000 epinephrine, (2) group buccal infiltration with 1.2 ml 2% lidocaine containing 80,000 epinephrine, (3) group buccal infiltration with 1.2 ml 4% articaine containing 1:100,000 epinephrine and palatinal infiltration with 0.5 ml 4% articaine containing 1:100,000 epinephrine, 4.group buccal infiltration with 1.2 ml 2% lidocaine containing 80.000 epinephrine and palatinal infiltration with 0.5 ml lidocaine containing 80.000 epinephrine. The pain intensity was measured by the Heft-Parker visual analog scale (VAS) before injection, during access cavity preparation and access palatal canal. The data were analyzed by the chi-square and The Kruskal–Wallis tests. Results Within the results of the study, no statistically significant difference was found between 4% articaine containing 1:100,000 epinephrine and 2% lidocaine containing 1:80,000 epinephrine in terms of anesthesia effectiveness (p > 0.05). When palatal infiltration anesthesia was applied in addition to buccal infiltration, the pain during entry into the palatal canals was significantly reduced compared to buccal infiltration anesthesia alone (p < 0.05). Conclusions According to the results of this study, it may be recommended to use palatal infiltration anesthesia in addition to buccal infiltration anesthesia, independent of the anesthetic solution, for an effective pulpal anesthesia in maxillary molars with irreversible pulpitis. Clinical trial registration Registration number is “NCT06342869” and date of registration is 2024-04-02.Retrospectively registered.https://doi.org/10.1186/s12903-025-05552-yArticaineLidocaineIrreversible pulpitisInfiltration anesthesiaMaxillary molar anesthesia
spellingShingle Duygu Kolay
Damla Kırıcı
Comparison of the effects of lidocaine and articaine used for buccal infiltration and supplemental palatinal infiltration anesthesia in maxillary molars with irreversible pulpitis: a prospective randomized study
BMC Oral Health
Articaine
Lidocaine
Irreversible pulpitis
Infiltration anesthesia
Maxillary molar anesthesia
title Comparison of the effects of lidocaine and articaine used for buccal infiltration and supplemental palatinal infiltration anesthesia in maxillary molars with irreversible pulpitis: a prospective randomized study
title_full Comparison of the effects of lidocaine and articaine used for buccal infiltration and supplemental palatinal infiltration anesthesia in maxillary molars with irreversible pulpitis: a prospective randomized study
title_fullStr Comparison of the effects of lidocaine and articaine used for buccal infiltration and supplemental palatinal infiltration anesthesia in maxillary molars with irreversible pulpitis: a prospective randomized study
title_full_unstemmed Comparison of the effects of lidocaine and articaine used for buccal infiltration and supplemental palatinal infiltration anesthesia in maxillary molars with irreversible pulpitis: a prospective randomized study
title_short Comparison of the effects of lidocaine and articaine used for buccal infiltration and supplemental palatinal infiltration anesthesia in maxillary molars with irreversible pulpitis: a prospective randomized study
title_sort comparison of the effects of lidocaine and articaine used for buccal infiltration and supplemental palatinal infiltration anesthesia in maxillary molars with irreversible pulpitis a prospective randomized study
topic Articaine
Lidocaine
Irreversible pulpitis
Infiltration anesthesia
Maxillary molar anesthesia
url https://doi.org/10.1186/s12903-025-05552-y
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AT damlakırıcı comparisonoftheeffectsoflidocaineandarticaineusedforbuccalinfiltrationandsupplementalpalatinalinfiltrationanesthesiainmaxillarymolarswithirreversiblepulpitisaprospectiverandomizedstudy