Caffeine consumption during pregnancy and ADHD at the age of 11 years: a birth cohort study
Objective Studies evaluating caffeine intake during pregnancy and long-term outcomes, such as the child's neurobehaviour, are still scarce and their results are inconsistent. The objective of the present study was to evaluate the association between maternal consumption of caffeine during pregn...
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BMJ Publishing Group
2016-12-01
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| Series: | BMJ Open |
| Online Access: | https://bmjopen.bmj.com/content/6/12/e012749.full |
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| author | Tiago N Munhoz Iná S Santos Alicia Matijasevich Luciana Anselmi Bianca Del-Ponte Luciana Tovo-Rodrigues |
| author_facet | Tiago N Munhoz Iná S Santos Alicia Matijasevich Luciana Anselmi Bianca Del-Ponte Luciana Tovo-Rodrigues |
| author_sort | Tiago N Munhoz |
| collection | DOAJ |
| description | Objective Studies evaluating caffeine intake during pregnancy and long-term outcomes, such as the child's neurobehaviour, are still scarce and their results are inconsistent. The objective of the present study was to evaluate the association between maternal consumption of caffeine during pregnancy and attention deficit hyperactivity disorder (ADHD) at the age of 11 years.Methodology All children born in the city of Pelotas, Brazil, during the year 2004, were selected for a cohort study. The mothers were interviewed at birth to obtain information on coffee and yerba mate consumption during pregnancy, among other matters. At the age of 11 years, presence of ADHD was evaluated using the Development and Well-Being Assessment (DAWBA) questionnaire, applied to the mothers. The prevalence of ADHD was calculated, with 95% CIs. The association between caffeine consumption and ADHD was tested by means of logistic regression.Results 3485 children were included in the analyses. The prevalence of ADHD was 4.1% (95% CI 3.4% to 4.7%): 5.8% (95% CI 4.7% to 6.9%) among boys and 2.3% (95% CI 1.5% to 3.0%) among girls. The prevalence of caffeine consumption during the entire pregnancy and in the first, second and third trimesters was 88.7% (87.7% to 89.7%), 86.5% (85.4% to 87.5%), 83.0% (81.8% to 84.2%) and 92.3% (91.4% to 93.1%), respectively. Caffeine consumption during the entire pregnancy and the first, second and third trimesters were not associated with ADHD in the crude or adjusted analysis.Conclusions The present study did not show any association between maternal caffeine consumption during pregnancy and ADHD at the age of 11 years. |
| format | Article |
| id | doaj-art-43b8b72de3ab4ac6b51a88a8a03ca884 |
| institution | Kabale University |
| issn | 2044-6055 |
| language | English |
| publishDate | 2016-12-01 |
| publisher | BMJ Publishing Group |
| record_format | Article |
| series | BMJ Open |
| spelling | doaj-art-43b8b72de3ab4ac6b51a88a8a03ca8842025-02-08T19:55:10ZengBMJ Publishing GroupBMJ Open2044-60552016-12-0161210.1136/bmjopen-2016-012749Caffeine consumption during pregnancy and ADHD at the age of 11 years: a birth cohort studyTiago N Munhoz0Iná S Santos1Alicia Matijasevich2Luciana Anselmi3Bianca Del-Ponte4Luciana Tovo-Rodrigues57 Department of Psychology, Federal University of Pelotas, Pelotas, Rio Grande do Sul, BrazilUniversidade Federal de Pelotas, Pelotas, Brazil4Postgraduate Program in Epidemiology, Federal University of Pelotas, Pelotas, Brazil1 Programa de Pós-graduação em Epidemiologia, Faculdade de Medicina, Universidade Federal de Pelotas, Pelotas, Brazil1Postgraduate Program in Epidemiology, Federal University of Pelotas, Pelotas, BrazilUniversidade Federal de Pelotas, Pelotas, BrazilObjective Studies evaluating caffeine intake during pregnancy and long-term outcomes, such as the child's neurobehaviour, are still scarce and their results are inconsistent. The objective of the present study was to evaluate the association between maternal consumption of caffeine during pregnancy and attention deficit hyperactivity disorder (ADHD) at the age of 11 years.Methodology All children born in the city of Pelotas, Brazil, during the year 2004, were selected for a cohort study. The mothers were interviewed at birth to obtain information on coffee and yerba mate consumption during pregnancy, among other matters. At the age of 11 years, presence of ADHD was evaluated using the Development and Well-Being Assessment (DAWBA) questionnaire, applied to the mothers. The prevalence of ADHD was calculated, with 95% CIs. The association between caffeine consumption and ADHD was tested by means of logistic regression.Results 3485 children were included in the analyses. The prevalence of ADHD was 4.1% (95% CI 3.4% to 4.7%): 5.8% (95% CI 4.7% to 6.9%) among boys and 2.3% (95% CI 1.5% to 3.0%) among girls. The prevalence of caffeine consumption during the entire pregnancy and in the first, second and third trimesters was 88.7% (87.7% to 89.7%), 86.5% (85.4% to 87.5%), 83.0% (81.8% to 84.2%) and 92.3% (91.4% to 93.1%), respectively. Caffeine consumption during the entire pregnancy and the first, second and third trimesters were not associated with ADHD in the crude or adjusted analysis.Conclusions The present study did not show any association between maternal caffeine consumption during pregnancy and ADHD at the age of 11 years.https://bmjopen.bmj.com/content/6/12/e012749.full |
| spellingShingle | Tiago N Munhoz Iná S Santos Alicia Matijasevich Luciana Anselmi Bianca Del-Ponte Luciana Tovo-Rodrigues Caffeine consumption during pregnancy and ADHD at the age of 11 years: a birth cohort study BMJ Open |
| title | Caffeine consumption during pregnancy and ADHD at the age of 11 years: a birth cohort study |
| title_full | Caffeine consumption during pregnancy and ADHD at the age of 11 years: a birth cohort study |
| title_fullStr | Caffeine consumption during pregnancy and ADHD at the age of 11 years: a birth cohort study |
| title_full_unstemmed | Caffeine consumption during pregnancy and ADHD at the age of 11 years: a birth cohort study |
| title_short | Caffeine consumption during pregnancy and ADHD at the age of 11 years: a birth cohort study |
| title_sort | caffeine consumption during pregnancy and adhd at the age of 11 years a birth cohort study |
| url | https://bmjopen.bmj.com/content/6/12/e012749.full |
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