Oocyte Cryopreservation: Retrospective Analysis of 5 Years Experience
OBJECTIVE: To analyze demographic and clinical data of patients who resorted to oocyte freezing between January 2014 and December 2018. STUDY DESIGN: Patients who applied to the Reproductive Endocrinology and Infertility Unit of Ankara University School of Medicine between January 2014 and Decemb...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Medical Network
2021-12-01
|
| Series: | Gynecology Obstetrics & Reproductive Medicine |
| Subjects: | |
| Online Access: | https://gorm.com.tr/index.php/GORM/article/view/1014 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1823857342049943552 |
|---|---|
| author | Halime Goktepe Esengul Turkyilmaz Gulsen Dogan Durdag Murat Sonmezer Cem Atabekoglu Batuhan Ozmen |
| author_facet | Halime Goktepe Esengul Turkyilmaz Gulsen Dogan Durdag Murat Sonmezer Cem Atabekoglu Batuhan Ozmen |
| author_sort | Halime Goktepe |
| collection | DOAJ |
| description |
OBJECTIVE: To analyze demographic and clinical data of patients who resorted to oocyte freezing between January 2014 and December 2018.
STUDY DESIGN: Patients who applied to the Reproductive Endocrinology and Infertility Unit of Ankara University School of Medicine between January 2014 and December 2018 with the request of oocyte freezing were included in this study. The files and computer records of the patients were analyzed retrospectively and sociodemographic, clinical and laboratory data were evaluated.
RESULTS: A total of 46 cycles were recorded in 40 patients over a 5-year period. The main indications were low ovarian reserve and/or advanced age (68.3%) and malignancy diagnosis (31.7%). There was a significant difference between elective fertility preservation and oncofertility preservation (Onco-FP) groups in terms of the age (38.4±4.7 vs 28.4±6.1; p=0.001). There was a significant difference between two groups in favor of oncofertility group in terms of anti-Mullerian hormone level, basal follicle-stimulating hormone level, antral follicle count, trigger day estradiol (E2) level, number of obtained oocytes, MII oocytes, and frozen oocytes
CONCLUSION: According to our study, the most prominent oocyte cryopreservation indication was advanced age and/or low ovarian reserve. The number of oocytes collected from patients in the Onco-FP group and thus the number of frozen oocytes was significantly higher than in the elective fertility preservation group, due to younger ages and better ovarian reserve in the Onco-FP group. Abdominal administration of the technique is particularly important for virgin patients in our country. Oocyte freezing is a fertility protection method available in a wide range of indications for reproductive-aged women.
|
| format | Article |
| id | doaj-art-45a67ce77c5443d0babfb69f788531e7 |
| institution | Kabale University |
| issn | 1300-4751 2602-4918 |
| language | English |
| publishDate | 2021-12-01 |
| publisher | Medical Network |
| record_format | Article |
| series | Gynecology Obstetrics & Reproductive Medicine |
| spelling | doaj-art-45a67ce77c5443d0babfb69f788531e72025-02-11T21:13:49ZengMedical NetworkGynecology Obstetrics & Reproductive Medicine1300-47512602-49182021-12-0127310.21613/GORM.2019.1014Oocyte Cryopreservation: Retrospective Analysis of 5 Years ExperienceHalime Goktepe0Esengul Turkyilmaz1Gulsen Dogan Durdag2Murat Sonmezer3Cem Atabekoglu4Batuhan Ozmen5Department of Gynecology and Obstetrics, Konya Education and Research Hospital, Konya, TurkeyDepartment of Gynecology and Obstetrics, Ankara Bilkent City Hospital, Ankara, TurkeyDepartment of Gynecology and Obstetrics, Başkent University, Faculty of Medicine, Adana Application and Research HospitalDepartment of Gynecology and Obstetrics, Ankara University, Faculty of Medicine, Ankara, TurkeyDepartment of Gynecology and Obstetrics, Ankara University, Faculty of Medicine, Ankara, TurkeyDepartment of Gynecology and Obstetrics, Ankara University, Faculty of Medicine, Ankara, Turkey OBJECTIVE: To analyze demographic and clinical data of patients who resorted to oocyte freezing between January 2014 and December 2018. STUDY DESIGN: Patients who applied to the Reproductive Endocrinology and Infertility Unit of Ankara University School of Medicine between January 2014 and December 2018 with the request of oocyte freezing were included in this study. The files and computer records of the patients were analyzed retrospectively and sociodemographic, clinical and laboratory data were evaluated. RESULTS: A total of 46 cycles were recorded in 40 patients over a 5-year period. The main indications were low ovarian reserve and/or advanced age (68.3%) and malignancy diagnosis (31.7%). There was a significant difference between elective fertility preservation and oncofertility preservation (Onco-FP) groups in terms of the age (38.4±4.7 vs 28.4±6.1; p=0.001). There was a significant difference between two groups in favor of oncofertility group in terms of anti-Mullerian hormone level, basal follicle-stimulating hormone level, antral follicle count, trigger day estradiol (E2) level, number of obtained oocytes, MII oocytes, and frozen oocytes CONCLUSION: According to our study, the most prominent oocyte cryopreservation indication was advanced age and/or low ovarian reserve. The number of oocytes collected from patients in the Onco-FP group and thus the number of frozen oocytes was significantly higher than in the elective fertility preservation group, due to younger ages and better ovarian reserve in the Onco-FP group. Abdominal administration of the technique is particularly important for virgin patients in our country. Oocyte freezing is a fertility protection method available in a wide range of indications for reproductive-aged women. https://gorm.com.tr/index.php/GORM/article/view/1014CryopreservationElective fertility preservationOocyteOncofertility preservation |
| spellingShingle | Halime Goktepe Esengul Turkyilmaz Gulsen Dogan Durdag Murat Sonmezer Cem Atabekoglu Batuhan Ozmen Oocyte Cryopreservation: Retrospective Analysis of 5 Years Experience Gynecology Obstetrics & Reproductive Medicine Cryopreservation Elective fertility preservation Oocyte Oncofertility preservation |
| title | Oocyte Cryopreservation: Retrospective Analysis of 5 Years Experience |
| title_full | Oocyte Cryopreservation: Retrospective Analysis of 5 Years Experience |
| title_fullStr | Oocyte Cryopreservation: Retrospective Analysis of 5 Years Experience |
| title_full_unstemmed | Oocyte Cryopreservation: Retrospective Analysis of 5 Years Experience |
| title_short | Oocyte Cryopreservation: Retrospective Analysis of 5 Years Experience |
| title_sort | oocyte cryopreservation retrospective analysis of 5 years experience |
| topic | Cryopreservation Elective fertility preservation Oocyte Oncofertility preservation |
| url | https://gorm.com.tr/index.php/GORM/article/view/1014 |
| work_keys_str_mv | AT halimegoktepe oocytecryopreservationretrospectiveanalysisof5yearsexperience AT esengulturkyilmaz oocytecryopreservationretrospectiveanalysisof5yearsexperience AT gulsendogandurdag oocytecryopreservationretrospectiveanalysisof5yearsexperience AT muratsonmezer oocytecryopreservationretrospectiveanalysisof5yearsexperience AT cematabekoglu oocytecryopreservationretrospectiveanalysisof5yearsexperience AT batuhanozmen oocytecryopreservationretrospectiveanalysisof5yearsexperience |