Relationship between Abnormal Lipid Metabolism and Gallstone Formation

Cholelithiasis is a common biliary system disease with a high incidence worldwide. Abnormal lipid metabolism has been shown to play a key role in the mechanism of gallstones. Therefore, recent research literature on the genes, proteins, and molecular substances involved in lipid metabolism during th...

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Main Authors: Xiang Li, Xiaodan Yin, Jun Xu, Lei Geng, Zhengtao Liu
Format: Article
Language:English
Published: Jin Publishing & Printing Co. 2025-01-01
Series:The Korean Journal of Gastroenterology
Subjects:
Online Access:https://www.kjg.or.kr/journal/view.html?uid=6075&vmd=Full
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author Xiang Li
Xiaodan Yin
Jun Xu
Lei Geng
Zhengtao Liu
author_facet Xiang Li
Xiaodan Yin
Jun Xu
Lei Geng
Zhengtao Liu
author_sort Xiang Li
collection DOAJ
description Cholelithiasis is a common biliary system disease with a high incidence worldwide. Abnormal lipid metabolism has been shown to play a key role in the mechanism of gallstones. Therefore, recent research literature on the genes, proteins, and molecular substances involved in lipid metabolism during the pathogenesis of gallstones has been conducted. This study aimed to determine the role of lipid metabolism in the pathogenesis of gallstones and provide insights for future studies using previous research in genomics, metabolomics, transcriptomics, and other fields.
format Article
id doaj-art-45fdefb4a12b40e4bfaf17b7dac4f55a
institution Kabale University
issn 1598-9992
2233-6869
language English
publishDate 2025-01-01
publisher Jin Publishing & Printing Co.
record_format Article
series The Korean Journal of Gastroenterology
spelling doaj-art-45fdefb4a12b40e4bfaf17b7dac4f55a2025-02-07T06:01:40ZengJin Publishing & Printing Co.The Korean Journal of Gastroenterology1598-99922233-68692025-01-01851112110.4166/kjg.2024.135Relationship between Abnormal Lipid Metabolism and Gallstone FormationXiang Li0Xiaodan Yin1Jun Xu2Lei Geng3https://orcid.org/0009-0006-8693-5721Zhengtao Liu4https://orcid.org/0009-0006-8693-5721Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou; NHC Key Laboratory of Combined Multi-organ Transplantation, Key Laboratory of the diagnosis and treatment of organ Transplantation, CAMS, First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou; Key Laboratory of Organ Transplantation, Zhejiang Province, First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, ChinaDivision of Hepatobiliary and Pancreatic Surgery, Department of Surgery, First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou; NHC Key Laboratory of Combined Multi-organ Transplantation, Key Laboratory of the diagnosis and treatment of organ Transplantation, CAMS, First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou; Key Laboratory of Organ Transplantation, Zhejiang Province, First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, ChinaDivision of Hepatobiliary and Pancreatic Surgery, Department of Surgery, First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou; NHC Key Laboratory of Combined Multi-organ Transplantation, Key Laboratory of the diagnosis and treatment of organ Transplantation, CAMS, First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou; Key Laboratory of Organ Transplantation, Zhejiang Province, First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, ChinaDivision of Hepatobiliary and Pancreatic Surgery, Department of Surgery, First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou; NHC Key Laboratory of Combined Multi-organ Transplantation, Key Laboratory of the diagnosis and treatment of organ Transplantation, CAMS, First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou; Key Laboratory of Organ Transplantation, Zhejiang Province, First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, ChinaShulan International Medical College, Zhejiang Shuren University, Hangzhou, Zhejiang4, ChinaCholelithiasis is a common biliary system disease with a high incidence worldwide. Abnormal lipid metabolism has been shown to play a key role in the mechanism of gallstones. Therefore, recent research literature on the genes, proteins, and molecular substances involved in lipid metabolism during the pathogenesis of gallstones has been conducted. This study aimed to determine the role of lipid metabolism in the pathogenesis of gallstones and provide insights for future studies using previous research in genomics, metabolomics, transcriptomics, and other fields.https://www.kjg.or.kr/journal/view.html?uid=6075&vmd=Fullgallstoneslipid metabolismtriglyceridesphospholipidsmetabolomics
spellingShingle Xiang Li
Xiaodan Yin
Jun Xu
Lei Geng
Zhengtao Liu
Relationship between Abnormal Lipid Metabolism and Gallstone Formation
The Korean Journal of Gastroenterology
gallstones
lipid metabolism
triglycerides
phospholipids
metabolomics
title Relationship between Abnormal Lipid Metabolism and Gallstone Formation
title_full Relationship between Abnormal Lipid Metabolism and Gallstone Formation
title_fullStr Relationship between Abnormal Lipid Metabolism and Gallstone Formation
title_full_unstemmed Relationship between Abnormal Lipid Metabolism and Gallstone Formation
title_short Relationship between Abnormal Lipid Metabolism and Gallstone Formation
title_sort relationship between abnormal lipid metabolism and gallstone formation
topic gallstones
lipid metabolism
triglycerides
phospholipids
metabolomics
url https://www.kjg.or.kr/journal/view.html?uid=6075&vmd=Full
work_keys_str_mv AT xiangli relationshipbetweenabnormallipidmetabolismandgallstoneformation
AT xiaodanyin relationshipbetweenabnormallipidmetabolismandgallstoneformation
AT junxu relationshipbetweenabnormallipidmetabolismandgallstoneformation
AT leigeng relationshipbetweenabnormallipidmetabolismandgallstoneformation
AT zhengtaoliu relationshipbetweenabnormallipidmetabolismandgallstoneformation