The knowledge mapping of traditional Chinese medicine for hepatocellular carcinoma: A bibliometric study
Introduction: Traditional Chinese medicine is widely used as adjuvant therapy for hepatocellular carcinoma (HCC), but no relevant bibliometric study has comprehensively analyzed the available data. Methods: To summarize the research landscape of traditional Chinese medicine (TCM) in relation to HCC...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-03-01
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| Series: | Pharmacological Research - Modern Chinese Medicine |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2667142525000107 |
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| author | Wenya Pei Boyu Jiao Zexiong Chen Jingchun Zeng Yancheng Fu Zhanmou Liang Baoguo Sun Jingwen Ruan Shijun Zhang |
| author_facet | Wenya Pei Boyu Jiao Zexiong Chen Jingchun Zeng Yancheng Fu Zhanmou Liang Baoguo Sun Jingwen Ruan Shijun Zhang |
| author_sort | Wenya Pei |
| collection | DOAJ |
| description | Introduction: Traditional Chinese medicine is widely used as adjuvant therapy for hepatocellular carcinoma (HCC), but no relevant bibliometric study has comprehensively analyzed the available data. Methods: To summarize the research landscape of traditional Chinese medicine (TCM) in relation to HCC over the past decade, publications on TCM and HCC from 2013 to 2023 were collected and analyzed using CiteSpace software. Results: A total of 1,160 articles on TCM for HCC were included in the bibliometric analysis, with the most productive countries and institutions located in the Asia region. The analysis indicated that traditional Chinese medicine may enhance immunity and regulate the local tumor microenvironment through mechanisms involving DNA damage, cell cycle arrest, and apoptosis by signaling pathways. Discussion: This study provides insights into the trends of traditional Chinese medicine for hepatocellular carcinoma, which may inform clinical practice and identify potential targets for further research. However, high-quality evidence-based research and rigorous mechanistic studies should be prioritized to explore new anticancer approaches. |
| format | Article |
| id | doaj-art-46122ab7baa343478d42cd15846ce85f |
| institution | Kabale University |
| issn | 2667-1425 |
| language | English |
| publishDate | 2025-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Pharmacological Research - Modern Chinese Medicine |
| spelling | doaj-art-46122ab7baa343478d42cd15846ce85f2025-02-08T05:01:36ZengElsevierPharmacological Research - Modern Chinese Medicine2667-14252025-03-0114100581The knowledge mapping of traditional Chinese medicine for hepatocellular carcinoma: A bibliometric studyWenya Pei0Boyu Jiao1Zexiong Chen2Jingchun Zeng3Yancheng Fu4Zhanmou Liang5Baoguo Sun6Jingwen Ruan7Shijun Zhang8Department of Acupuncture, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, ChinaDepartment of Human Anatomy and Physiology, Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, Guangdong, ChinaDepartment of Traditional Chinese Medicine, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, ChinaDepartment of Rehabilitation, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, ChinaDepartment of Acupuncture, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, ChinaDepartment of Acupuncture, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, ChinaDepartment of Traditional Chinese Medicine, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China; Corresponding authors at: The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China.Department of Acupuncture, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China; Corresponding authors at: The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China.Department of Traditional Chinese Medicine, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China; Corresponding authors at: The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China.Introduction: Traditional Chinese medicine is widely used as adjuvant therapy for hepatocellular carcinoma (HCC), but no relevant bibliometric study has comprehensively analyzed the available data. Methods: To summarize the research landscape of traditional Chinese medicine (TCM) in relation to HCC over the past decade, publications on TCM and HCC from 2013 to 2023 were collected and analyzed using CiteSpace software. Results: A total of 1,160 articles on TCM for HCC were included in the bibliometric analysis, with the most productive countries and institutions located in the Asia region. The analysis indicated that traditional Chinese medicine may enhance immunity and regulate the local tumor microenvironment through mechanisms involving DNA damage, cell cycle arrest, and apoptosis by signaling pathways. Discussion: This study provides insights into the trends of traditional Chinese medicine for hepatocellular carcinoma, which may inform clinical practice and identify potential targets for further research. However, high-quality evidence-based research and rigorous mechanistic studies should be prioritized to explore new anticancer approaches.http://www.sciencedirect.com/science/article/pii/S2667142525000107Traditional Chinese medicineHepatocellular carcinomaBibliometric analysisCiteSpaceResearch hotspot |
| spellingShingle | Wenya Pei Boyu Jiao Zexiong Chen Jingchun Zeng Yancheng Fu Zhanmou Liang Baoguo Sun Jingwen Ruan Shijun Zhang The knowledge mapping of traditional Chinese medicine for hepatocellular carcinoma: A bibliometric study Pharmacological Research - Modern Chinese Medicine Traditional Chinese medicine Hepatocellular carcinoma Bibliometric analysis CiteSpace Research hotspot |
| title | The knowledge mapping of traditional Chinese medicine for hepatocellular carcinoma: A bibliometric study |
| title_full | The knowledge mapping of traditional Chinese medicine for hepatocellular carcinoma: A bibliometric study |
| title_fullStr | The knowledge mapping of traditional Chinese medicine for hepatocellular carcinoma: A bibliometric study |
| title_full_unstemmed | The knowledge mapping of traditional Chinese medicine for hepatocellular carcinoma: A bibliometric study |
| title_short | The knowledge mapping of traditional Chinese medicine for hepatocellular carcinoma: A bibliometric study |
| title_sort | knowledge mapping of traditional chinese medicine for hepatocellular carcinoma a bibliometric study |
| topic | Traditional Chinese medicine Hepatocellular carcinoma Bibliometric analysis CiteSpace Research hotspot |
| url | http://www.sciencedirect.com/science/article/pii/S2667142525000107 |
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