Drug-induced liver injuries
The aim of review. To demonstrate modern concept on management and prevention in patients with drug-induced liver injury (DILI).Key points. DILI have a wide spectrum of clinical symptoms, from asymptomatic elevation of serum transaminase activity to fulminant liver failure. The task of clinician – t...
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| Format: | Article |
| Language: | Russian |
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Gastro LLC
2014-07-01
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| Series: | Российский журнал гастроэнтерологии, гепатологии, колопроктологии |
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| Online Access: | https://www.gastro-j.ru/jour/article/view/1087 |
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| _version_ | 1823860188736651264 |
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| author | S. F. Galimova |
| author_facet | S. F. Galimova |
| author_sort | S. F. Galimova |
| collection | DOAJ |
| description | The aim of review. To demonstrate modern concept on management and prevention in patients with drug-induced liver injury (DILI).Key points. DILI have a wide spectrum of clinical symptoms, from asymptomatic elevation of serum transaminase activity to fulminant liver failure. The task of clinician – to withdraw a «causative» drug and under indications to prescribe specific and/or symptomatic treatment in due time. Preventive measures include global control of clinical and postmarketing investigations. Observation of mode of intake of the drug, analysis of risk factors, polypragmasy, drug interactions, carrying out of appropriate investigation at prescription of potentially hepatotoxic drugs lays at the basis of prevention concerning the specific patient. |
| format | Article |
| id | doaj-art-46815d61fa92493fa5577c62b6c9fa70 |
| institution | Kabale University |
| issn | 1382-4376 2658-6673 |
| language | Russian |
| publishDate | 2014-07-01 |
| publisher | Gastro LLC |
| record_format | Article |
| series | Российский журнал гастроэнтерологии, гепатологии, колопроктологии |
| spelling | doaj-art-46815d61fa92493fa5577c62b6c9fa702025-02-10T16:14:33ZrusGastro LLCРоссийский журнал гастроэнтерологии, гепатологии, колопроктологии1382-43762658-66732014-07-012412128688Drug-induced liver injuriesS. F. Galimova0State educational government-financed institution of higher professional education «Sechenov First Moscow State Medical University» Ministry of Health and Social Development of RussiaThe aim of review. To demonstrate modern concept on management and prevention in patients with drug-induced liver injury (DILI).Key points. DILI have a wide spectrum of clinical symptoms, from asymptomatic elevation of serum transaminase activity to fulminant liver failure. The task of clinician – to withdraw a «causative» drug and under indications to prescribe specific and/or symptomatic treatment in due time. Preventive measures include global control of clinical and postmarketing investigations. Observation of mode of intake of the drug, analysis of risk factors, polypragmasy, drug interactions, carrying out of appropriate investigation at prescription of potentially hepatotoxic drugs lays at the basis of prevention concerning the specific patient.https://www.gastro-j.ru/jour/article/view/1087drug-induced liver injurypreventionmanagement of the patientguidelines |
| spellingShingle | S. F. Galimova Drug-induced liver injuries Российский журнал гастроэнтерологии, гепатологии, колопроктологии drug-induced liver injury prevention management of the patient guidelines |
| title | Drug-induced liver injuries |
| title_full | Drug-induced liver injuries |
| title_fullStr | Drug-induced liver injuries |
| title_full_unstemmed | Drug-induced liver injuries |
| title_short | Drug-induced liver injuries |
| title_sort | drug induced liver injuries |
| topic | drug-induced liver injury prevention management of the patient guidelines |
| url | https://www.gastro-j.ru/jour/article/view/1087 |
| work_keys_str_mv | AT sfgalimova druginducedliverinjuries |