Animal models of hemorrhage, parameters, and development of hemostatic methods
Abstract Hemorrhage is a prevalent side effect of various injuries and can be life-threatening in certain instances. It is categorized into compressible and non-compressible types, each necessitating distinct modeling, laboratory assessments, and hemostatic approaches. This study utilized the keywor...
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| Format: | Article |
| Language: | English |
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BMC
2025-02-01
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| Series: | Laboratory Animal Research |
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| Online Access: | https://doi.org/10.1186/s42826-025-00239-5 |
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| author | Gholamhossien Darya Hamid Mohammadi Zeinab Dehghan Alireza Nakhaei Amin Derakhshanfar |
| author_facet | Gholamhossien Darya Hamid Mohammadi Zeinab Dehghan Alireza Nakhaei Amin Derakhshanfar |
| author_sort | Gholamhossien Darya |
| collection | DOAJ |
| description | Abstract Hemorrhage is a prevalent side effect of various injuries and can be life-threatening in certain instances. It is categorized into compressible and non-compressible types, each necessitating distinct modeling, laboratory assessments, and hemostatic approaches. This study utilized the keywords Hemorrhage, Bleeding, Animal Modeling, and Hemostat in reputable databases. The findings indicate that femoral artery hemorrhage and hepatic parenchymal hemorrhage are the predominant modeling techniques for compressible and non-compressible bleeding, respectively. Furthermore, it is noted that animal models of compressible hemorrhages are primarily situated in superficial body areas to investigate dressing or additive hemostats, while non-compressible hemorrhage models, typically located in visceral organs, are employed to examine adhesive or surgical instrument-based hemostats. |
| format | Article |
| id | doaj-art-496d267fa98240f199cc61409aba435f |
| institution | Kabale University |
| issn | 2233-7660 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | BMC |
| record_format | Article |
| series | Laboratory Animal Research |
| spelling | doaj-art-496d267fa98240f199cc61409aba435f2025-02-09T12:09:16ZengBMCLaboratory Animal Research2233-76602025-02-0141111410.1186/s42826-025-00239-5Animal models of hemorrhage, parameters, and development of hemostatic methodsGholamhossien Darya0Hamid Mohammadi1Zeinab Dehghan2Alireza Nakhaei3Amin Derakhshanfar4Department of Comparative Biomedical Sciences, School of Advanced Medical Sciences and Technologies, Shiraz University of Medical SciencesDepartment of Pediatric, School of Medicine, Shiraz University of Medical SciencesDepartment of Comparative Biomedical Sciences, School of Advanced Medical Sciences and Technologies, Shiraz University of Medical SciencesDepartment of Comparative Biomedical Sciences, School of Advanced Medical Sciences and Technologies, Shiraz University of Medical SciencesDepartment of Comparative Biomedical Sciences, School of Advanced Medical Sciences and Technologies, Shiraz University of Medical SciencesAbstract Hemorrhage is a prevalent side effect of various injuries and can be life-threatening in certain instances. It is categorized into compressible and non-compressible types, each necessitating distinct modeling, laboratory assessments, and hemostatic approaches. This study utilized the keywords Hemorrhage, Bleeding, Animal Modeling, and Hemostat in reputable databases. The findings indicate that femoral artery hemorrhage and hepatic parenchymal hemorrhage are the predominant modeling techniques for compressible and non-compressible bleeding, respectively. Furthermore, it is noted that animal models of compressible hemorrhages are primarily situated in superficial body areas to investigate dressing or additive hemostats, while non-compressible hemorrhage models, typically located in visceral organs, are employed to examine adhesive or surgical instrument-based hemostats.https://doi.org/10.1186/s42826-025-00239-5HemorrhageBleedingAnimal modelingHemostat |
| spellingShingle | Gholamhossien Darya Hamid Mohammadi Zeinab Dehghan Alireza Nakhaei Amin Derakhshanfar Animal models of hemorrhage, parameters, and development of hemostatic methods Laboratory Animal Research Hemorrhage Bleeding Animal modeling Hemostat |
| title | Animal models of hemorrhage, parameters, and development of hemostatic methods |
| title_full | Animal models of hemorrhage, parameters, and development of hemostatic methods |
| title_fullStr | Animal models of hemorrhage, parameters, and development of hemostatic methods |
| title_full_unstemmed | Animal models of hemorrhage, parameters, and development of hemostatic methods |
| title_short | Animal models of hemorrhage, parameters, and development of hemostatic methods |
| title_sort | animal models of hemorrhage parameters and development of hemostatic methods |
| topic | Hemorrhage Bleeding Animal modeling Hemostat |
| url | https://doi.org/10.1186/s42826-025-00239-5 |
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