Treatment compliance at initial and maintenance therapy at gastroesophageal reflux disease
Aim of investigation. To analyze treatment compliance at initial course and maintenance treatment by proton pump inhibitors at gastroesophageal reflux disease (GERD). Material and methods. Overall 84 GERD patients with took part in prospective study: 50 (59.5%) men and 34 (40.5%) women aged from 18...
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| Language: | Russian |
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Gastro LLC
2018-08-01
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| Series: | Российский журнал гастроэнтерологии, гепатологии, колопроктологии |
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| Online Access: | https://www.gastro-j.ru/jour/article/view/120 |
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| author | V. I. Simanenkov S. V. Tikhonov N. B. Lischuk |
| author_facet | V. I. Simanenkov S. V. Tikhonov N. B. Lischuk |
| author_sort | V. I. Simanenkov |
| collection | DOAJ |
| description | Aim of investigation. To analyze treatment compliance at initial course and maintenance treatment by proton pump inhibitors at gastroesophageal reflux disease (GERD). Material and methods. Overall 84 GERD patients with took part in prospective study: 50 (59.5%) men and 34 (40.5%) women aged from 18 to 74 years. By results of esophagogastroduodenoscopy and morphological investigation of mucosal biopsies non-erosive reflux disease (NERD) was diagnosed in 32 (38.1%) patients, reflux esophagitis was found in 52 cases (61.9%). Total period of patients monitoring was 12 months at which patients made five visits to the research center: initial, through 1.5, 3, 6 and 12 months with filling in of questionnaires of Spielberger-Khanin, Beck, SF-36 and abridged multifactorial questionnaire of the personality (AMQP). Treatment compliance was established according to duration of study participation, along with that patients self-estimated it on 2, 3, 4 and 5 visits by Morisky-Green test and 5-score analog scales of pharmaceutical treatment compliance and lifestyle verification. The first visit patients underwent 1:1 randomization to the educational program devoted to reflux disease. Results. Of all patients 17.9% missed the second visit, the logistic regression analysis revealed no factors associated to the early low compliance; 38% of patients made all five visits for 12 months. The latter differed significantly from those who dropped out of the study at different stages: they had high number of chronic diseases (р |
| format | Article |
| id | doaj-art-49a7c701d71744828d9564d3a22bf39b |
| institution | Kabale University |
| issn | 1382-4376 2658-6673 |
| language | Russian |
| publishDate | 2018-08-01 |
| publisher | Gastro LLC |
| record_format | Article |
| series | Российский журнал гастроэнтерологии, гепатологии, колопроктологии |
| spelling | doaj-art-49a7c701d71744828d9564d3a22bf39b2025-02-10T16:14:28ZrusGastro LLCРоссийский журнал гастроэнтерологии, гепатологии, колопроктологии1382-43762658-66732018-08-01271293410.22416/1382-4376-2017-27-1-29-34120Treatment compliance at initial and maintenance therapy at gastroesophageal reflux diseaseV. I. Simanenkov0S. V. Tikhonov1N. B. Lischuk2Mechnikov North-Western State Medical UniversityMechnikov North-Western State Medical UniversityMechnikov North-Western State Medical UniversityAim of investigation. To analyze treatment compliance at initial course and maintenance treatment by proton pump inhibitors at gastroesophageal reflux disease (GERD). Material and methods. Overall 84 GERD patients with took part in prospective study: 50 (59.5%) men and 34 (40.5%) women aged from 18 to 74 years. By results of esophagogastroduodenoscopy and morphological investigation of mucosal biopsies non-erosive reflux disease (NERD) was diagnosed in 32 (38.1%) patients, reflux esophagitis was found in 52 cases (61.9%). Total period of patients monitoring was 12 months at which patients made five visits to the research center: initial, through 1.5, 3, 6 and 12 months with filling in of questionnaires of Spielberger-Khanin, Beck, SF-36 and abridged multifactorial questionnaire of the personality (AMQP). Treatment compliance was established according to duration of study participation, along with that patients self-estimated it on 2, 3, 4 and 5 visits by Morisky-Green test and 5-score analog scales of pharmaceutical treatment compliance and lifestyle verification. The first visit patients underwent 1:1 randomization to the educational program devoted to reflux disease. Results. Of all patients 17.9% missed the second visit, the logistic regression analysis revealed no factors associated to the early low compliance; 38% of patients made all five visits for 12 months. The latter differed significantly from those who dropped out of the study at different stages: they had high number of chronic diseases (рhttps://www.gastro-j.ru/jour/article/view/120гастроэзофагеальная рефлюксная болезньприверженность к лечениюингибиторы протонной помпыобразовательная программаподдерживающая терапия |
| spellingShingle | V. I. Simanenkov S. V. Tikhonov N. B. Lischuk Treatment compliance at initial and maintenance therapy at gastroesophageal reflux disease Российский журнал гастроэнтерологии, гепатологии, колопроктологии гастроэзофагеальная рефлюксная болезнь приверженность к лечению ингибиторы протонной помпы образовательная программа поддерживающая терапия |
| title | Treatment compliance at initial and maintenance therapy at gastroesophageal reflux disease |
| title_full | Treatment compliance at initial and maintenance therapy at gastroesophageal reflux disease |
| title_fullStr | Treatment compliance at initial and maintenance therapy at gastroesophageal reflux disease |
| title_full_unstemmed | Treatment compliance at initial and maintenance therapy at gastroesophageal reflux disease |
| title_short | Treatment compliance at initial and maintenance therapy at gastroesophageal reflux disease |
| title_sort | treatment compliance at initial and maintenance therapy at gastroesophageal reflux disease |
| topic | гастроэзофагеальная рефлюксная болезнь приверженность к лечению ингибиторы протонной помпы образовательная программа поддерживающая терапия |
| url | https://www.gastro-j.ru/jour/article/view/120 |
| work_keys_str_mv | AT visimanenkov treatmentcomplianceatinitialandmaintenancetherapyatgastroesophagealrefluxdisease AT svtikhonov treatmentcomplianceatinitialandmaintenancetherapyatgastroesophagealrefluxdisease AT nblischuk treatmentcomplianceatinitialandmaintenancetherapyatgastroesophagealrefluxdisease |