The use of Platelet Rich Plasmain combination of guided tissue regeneration (chitosan) for bone defects: homogeneity analysis.

Background and objective Guided bone regeneration is an accepted surgical procedure intended to increase the quantity and quality of host bone in localized defects of the alveolar bone. In this investigation, a novel combination by mixing of Platelet Rich Plasma (PRP) with the chitosan solution ha...

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Main Authors: Dildar Abdullah Othman, Ziwar Ahmed Saleh, Raid Fahim Salman
Format: Article
Language:English
Published: College Of Dentistry Hawler Medical University 2022-12-01
Series:Erbil Dental Journal
Subjects:
Online Access:https://edj.hmu.edu.krd/index.php/journal/article/view/185
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author Dildar Abdullah Othman
Ziwar Ahmed Saleh
Raid Fahim Salman
author_facet Dildar Abdullah Othman
Ziwar Ahmed Saleh
Raid Fahim Salman
author_sort Dildar Abdullah Othman
collection DOAJ
description Background and objective Guided bone regeneration is an accepted surgical procedure intended to increase the quantity and quality of host bone in localized defects of the alveolar bone. In this investigation, a novel combination by mixing of Platelet Rich Plasma (PRP) with the chitosan solution has been prepared. Method In method Platelet-rich plasma was prepared and mixed with chitosan in three different ratios (80:20, 90:10 and 95:5) the homogeneity status of the utilized samples has been studied using scanning electron microscopy (SEM), energy dispersive X-ray (EDS) analysis and FT-IR spectroscopy techniques. Results The result showed The homogeneity status of the utilized samples has been studied scanning electron microscopy (SEM), energy dispersive X-ray (EDX) analysis and FT-IR spectroscopy techniques SEM Bigger cracks and obvious gaps can be seen clearly in the 20:80 ratio sample which shows the adhesion failure between PRP and chitosan in this mixture. By energy dispersive X-ray (EDX) It can be seen, that carbon percentages, which belong to chitosan, is a vital parameter that shows the optimum percentage for the formation of a homogeneous PRPchitosan compound and FTIR show the homogenous mixing without chemical changing of the mixture and showed the preservation of the chemical properties of each content. Conclusion The study concluded The homogeneity status of different ratios of novel material (mixture of PRP / Chitosan) revealed that 95:5 ratio was preferable to test for biocompatibility and bone regeneration.
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institution Kabale University
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language English
publishDate 2022-12-01
publisher College Of Dentistry Hawler Medical University
record_format Article
series Erbil Dental Journal
spelling doaj-art-4bed626926a7412497132577d2f1470c2025-02-10T20:48:21ZengCollege Of Dentistry Hawler Medical UniversityErbil Dental Journal2523-61722616-47952022-12-0152The use of Platelet Rich Plasmain combination of guided tissue regeneration (chitosan) for bone defects: homogeneity analysis.Dildar Abdullah Othman0 Ziwar Ahmed SalehRaid Fahim Salman1Department of Periodontology, College of Dentistry, Hawler Medical University, Erbil, Iraq.Department of Conservative Dentistry, College of Dentistry, Hawler Medical University, Erbil, Iraq. Background and objective Guided bone regeneration is an accepted surgical procedure intended to increase the quantity and quality of host bone in localized defects of the alveolar bone. In this investigation, a novel combination by mixing of Platelet Rich Plasma (PRP) with the chitosan solution has been prepared. Method In method Platelet-rich plasma was prepared and mixed with chitosan in three different ratios (80:20, 90:10 and 95:5) the homogeneity status of the utilized samples has been studied using scanning electron microscopy (SEM), energy dispersive X-ray (EDS) analysis and FT-IR spectroscopy techniques. Results The result showed The homogeneity status of the utilized samples has been studied scanning electron microscopy (SEM), energy dispersive X-ray (EDX) analysis and FT-IR spectroscopy techniques SEM Bigger cracks and obvious gaps can be seen clearly in the 20:80 ratio sample which shows the adhesion failure between PRP and chitosan in this mixture. By energy dispersive X-ray (EDX) It can be seen, that carbon percentages, which belong to chitosan, is a vital parameter that shows the optimum percentage for the formation of a homogeneous PRPchitosan compound and FTIR show the homogenous mixing without chemical changing of the mixture and showed the preservation of the chemical properties of each content. Conclusion The study concluded The homogeneity status of different ratios of novel material (mixture of PRP / Chitosan) revealed that 95:5 ratio was preferable to test for biocompatibility and bone regeneration. https://edj.hmu.edu.krd/index.php/journal/article/view/185PRPChitosanscanning electron microscope (SEM)energy dispersive X-ray (EDS)FTIR
spellingShingle Dildar Abdullah Othman
Ziwar Ahmed Saleh
Raid Fahim Salman
The use of Platelet Rich Plasmain combination of guided tissue regeneration (chitosan) for bone defects: homogeneity analysis.
Erbil Dental Journal
PRP
Chitosan
scanning electron microscope (SEM)
energy dispersive X-ray (EDS)
FTIR
title The use of Platelet Rich Plasmain combination of guided tissue regeneration (chitosan) for bone defects: homogeneity analysis.
title_full The use of Platelet Rich Plasmain combination of guided tissue regeneration (chitosan) for bone defects: homogeneity analysis.
title_fullStr The use of Platelet Rich Plasmain combination of guided tissue regeneration (chitosan) for bone defects: homogeneity analysis.
title_full_unstemmed The use of Platelet Rich Plasmain combination of guided tissue regeneration (chitosan) for bone defects: homogeneity analysis.
title_short The use of Platelet Rich Plasmain combination of guided tissue regeneration (chitosan) for bone defects: homogeneity analysis.
title_sort use of platelet rich plasmain combination of guided tissue regeneration chitosan for bone defects homogeneity analysis
topic PRP
Chitosan
scanning electron microscope (SEM)
energy dispersive X-ray (EDS)
FTIR
url https://edj.hmu.edu.krd/index.php/journal/article/view/185
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