Mucocutaneous Changes in End-Stage Renal Disease under Regular Hemodialysis - A Cross-Sectional Study

Introduction: Patients with end-stage renal disease (ESRD) suffer from mucocutaneous changes that could significantly impair the quality of life. We aimed this study to assess the mucocutaneous changes in hemodialysis patients and to correlate the serum creatinine to these changes. Methods: Data wer...

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Main Authors: Asmaa A. Ras, Nevine H. Kheir El Din, Ashraf M. Talaat, Radwa R. Hussein, Eman Khalil
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2023-04-01
Series:Indian Journal of Dental Research
Subjects:
Online Access:https://journals.lww.com/10.4103/ijdr.IJDR_802_20
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author Asmaa A. Ras
Nevine H. Kheir El Din
Ashraf M. Talaat
Radwa R. Hussein
Eman Khalil
author_facet Asmaa A. Ras
Nevine H. Kheir El Din
Ashraf M. Talaat
Radwa R. Hussein
Eman Khalil
author_sort Asmaa A. Ras
collection DOAJ
description Introduction: Patients with end-stage renal disease (ESRD) suffer from mucocutaneous changes that could significantly impair the quality of life. We aimed this study to assess the mucocutaneous changes in hemodialysis patients and to correlate the serum creatinine to these changes. Methods: Data were collected from the Hemodialysis Center at Benha University. A cross-sectional study design on 130 chronic kidney disease (CKD) patients (30-60 years old, 84 males, 46 females) undergoing hemodialysis. Oral examinations were done for these patients as per the modified World Health Organization oral health survey 2013 criteria. All the mucocutaneous changes were recorded then types, distribution, and frequencies were calculated and correlated to serum creatinine. Results: Mucocutaneous abnormalities were present in 100% of the studied CKD sample. We observed that pallor (76.2%), xerostomia (70%), petechiae/purpura (49.2%), altered taste (49.2%), and lip pigmentation (40.8%) were the most prevalent mucocutaneous changes among the CKD patients undergoing hemodialysis. A strong association was detected between serum creatinine and the following: abnormal lip pigmentation and lichen planus. Discussion: There is an association between lip pigmentation and lichen planus in CKD patients and the level of serum creatinine as the higher level of serum creatinine was found in the patients with abnormal lip pigmentation and the atrophic lichen planus patients.
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1998-3603
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spelling doaj-art-4de45990e9564a31914acade78f3816e2025-02-09T09:38:05ZengWolters Kluwer Medknow PublicationsIndian Journal of Dental Research0970-92901998-36032023-04-0134213013510.4103/ijdr.IJDR_802_20Mucocutaneous Changes in End-Stage Renal Disease under Regular Hemodialysis - A Cross-Sectional StudyAsmaa A. RasNevine H. Kheir El DinAshraf M. TalaatRadwa R. HusseinEman KhalilIntroduction: Patients with end-stage renal disease (ESRD) suffer from mucocutaneous changes that could significantly impair the quality of life. We aimed this study to assess the mucocutaneous changes in hemodialysis patients and to correlate the serum creatinine to these changes. Methods: Data were collected from the Hemodialysis Center at Benha University. A cross-sectional study design on 130 chronic kidney disease (CKD) patients (30-60 years old, 84 males, 46 females) undergoing hemodialysis. Oral examinations were done for these patients as per the modified World Health Organization oral health survey 2013 criteria. All the mucocutaneous changes were recorded then types, distribution, and frequencies were calculated and correlated to serum creatinine. Results: Mucocutaneous abnormalities were present in 100% of the studied CKD sample. We observed that pallor (76.2%), xerostomia (70%), petechiae/purpura (49.2%), altered taste (49.2%), and lip pigmentation (40.8%) were the most prevalent mucocutaneous changes among the CKD patients undergoing hemodialysis. A strong association was detected between serum creatinine and the following: abnormal lip pigmentation and lichen planus. Discussion: There is an association between lip pigmentation and lichen planus in CKD patients and the level of serum creatinine as the higher level of serum creatinine was found in the patients with abnormal lip pigmentation and the atrophic lichen planus patients.https://journals.lww.com/10.4103/ijdr.IJDR_802_20creatinineesrdhemodialysismucocutaneous
spellingShingle Asmaa A. Ras
Nevine H. Kheir El Din
Ashraf M. Talaat
Radwa R. Hussein
Eman Khalil
Mucocutaneous Changes in End-Stage Renal Disease under Regular Hemodialysis - A Cross-Sectional Study
Indian Journal of Dental Research
creatinine
esrd
hemodialysis
mucocutaneous
title Mucocutaneous Changes in End-Stage Renal Disease under Regular Hemodialysis - A Cross-Sectional Study
title_full Mucocutaneous Changes in End-Stage Renal Disease under Regular Hemodialysis - A Cross-Sectional Study
title_fullStr Mucocutaneous Changes in End-Stage Renal Disease under Regular Hemodialysis - A Cross-Sectional Study
title_full_unstemmed Mucocutaneous Changes in End-Stage Renal Disease under Regular Hemodialysis - A Cross-Sectional Study
title_short Mucocutaneous Changes in End-Stage Renal Disease under Regular Hemodialysis - A Cross-Sectional Study
title_sort mucocutaneous changes in end stage renal disease under regular hemodialysis a cross sectional study
topic creatinine
esrd
hemodialysis
mucocutaneous
url https://journals.lww.com/10.4103/ijdr.IJDR_802_20
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AT ashrafmtalaat mucocutaneouschangesinendstagerenaldiseaseunderregularhemodialysisacrosssectionalstudy
AT radwarhussein mucocutaneouschangesinendstagerenaldiseaseunderregularhemodialysisacrosssectionalstudy
AT emankhalil mucocutaneouschangesinendstagerenaldiseaseunderregularhemodialysisacrosssectionalstudy