Disparate and shared transcriptomic signatures associated with cortical atrophy in genetic behavioral variant frontotemporal degeneration
Abstract Background Cortical atrophy is a common manifestation in behavioral variant frontotemporal degeneration (bvFTD), exhibiting spatial heterogeneity across various genetic subgroups, which may be driven by distinct biological mechanisms. Methods We employed an integrative imaging transcriptomi...
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Main Authors: | Ting Shen, Jacob W. Vogel, Vivianna M. Van Deerlin, EunRan Suh, Laynie Dratch, Jeffrey S. Phillips, Lauren Massimo, Edward B. Lee, David J. Irwin, Corey T. McMillan |
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Format: | Article |
Language: | English |
Published: |
BMC
2025-02-01
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Series: | Molecular Neurodegeneration |
Subjects: | |
Online Access: | https://doi.org/10.1186/s13024-025-00806-3 |
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