Machine Learning for Precision Health Economics and Outcomes Research (P-HEOR): Conceptual Review of Applications and Next Steps

Precision health economics and outcomes research (P-HEOR) integrates economic and clinical value assessment by explicitly discovering distinct clinical and health care utilization phenotypes among patients. Through a conceptualized example, the objective of this review is to highlight the capabiliti...

Full description

Saved in:
Bibliographic Details
Main Authors: Yixi Chen, Viktor V Chirikov, Xiaocong L Marston, Jingang Yang, Haibo Qiu, Jianfeng Xie, Ning Sun, Chengming Gu, Peng Dong, Xin Gao
Format: Article
Language:English
Published: Columbia Data Analytics, LLC 2020-05-01
Series:Journal of Health Economics and Outcomes Research
Online Access:https://doi.org/10.36469/jheor.2020.12698
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1823860339962281984
author Yixi Chen
Viktor V Chirikov
Xiaocong L Marston
Jingang Yang
Haibo Qiu
Jianfeng Xie
Ning Sun
Chengming Gu
Peng Dong
Xin Gao
author_facet Yixi Chen
Viktor V Chirikov
Xiaocong L Marston
Jingang Yang
Haibo Qiu
Jianfeng Xie
Ning Sun
Chengming Gu
Peng Dong
Xin Gao
author_sort Yixi Chen
collection DOAJ
description Precision health economics and outcomes research (P-HEOR) integrates economic and clinical value assessment by explicitly discovering distinct clinical and health care utilization phenotypes among patients. Through a conceptualized example, the objective of this review is to highlight the capabilities and limitations of machine learning (ML) applications to P-HEOR and to contextualize the potential opportunities and challenges for the wide adoption of ML for health economics. We outline a P-HEOR conceptual framework extending the ML methodology to comparatively assess the economic value of treatment regimens. Latest methodology developments on bias and confounding control in ML applications to precision medicine are also summarized.
format Article
id doaj-art-4ea1832a4be94f1b90ab371aae3ebcf2
institution Kabale University
issn 2327-2236
language English
publishDate 2020-05-01
publisher Columbia Data Analytics, LLC
record_format Article
series Journal of Health Economics and Outcomes Research
spelling doaj-art-4ea1832a4be94f1b90ab371aae3ebcf22025-02-10T16:13:02ZengColumbia Data Analytics, LLCJournal of Health Economics and Outcomes Research2327-22362020-05-0171Machine Learning for Precision Health Economics and Outcomes Research (P-HEOR): Conceptual Review of Applications and Next StepsYixi ChenViktor V ChirikovXiaocong L MarstonJingang YangHaibo QiuJianfeng XieNing SunChengming GuPeng DongXin GaoPrecision health economics and outcomes research (P-HEOR) integrates economic and clinical value assessment by explicitly discovering distinct clinical and health care utilization phenotypes among patients. Through a conceptualized example, the objective of this review is to highlight the capabilities and limitations of machine learning (ML) applications to P-HEOR and to contextualize the potential opportunities and challenges for the wide adoption of ML for health economics. We outline a P-HEOR conceptual framework extending the ML methodology to comparatively assess the economic value of treatment regimens. Latest methodology developments on bias and confounding control in ML applications to precision medicine are also summarized.https://doi.org/10.36469/jheor.2020.12698
spellingShingle Yixi Chen
Viktor V Chirikov
Xiaocong L Marston
Jingang Yang
Haibo Qiu
Jianfeng Xie
Ning Sun
Chengming Gu
Peng Dong
Xin Gao
Machine Learning for Precision Health Economics and Outcomes Research (P-HEOR): Conceptual Review of Applications and Next Steps
Journal of Health Economics and Outcomes Research
title Machine Learning for Precision Health Economics and Outcomes Research (P-HEOR): Conceptual Review of Applications and Next Steps
title_full Machine Learning for Precision Health Economics and Outcomes Research (P-HEOR): Conceptual Review of Applications and Next Steps
title_fullStr Machine Learning for Precision Health Economics and Outcomes Research (P-HEOR): Conceptual Review of Applications and Next Steps
title_full_unstemmed Machine Learning for Precision Health Economics and Outcomes Research (P-HEOR): Conceptual Review of Applications and Next Steps
title_short Machine Learning for Precision Health Economics and Outcomes Research (P-HEOR): Conceptual Review of Applications and Next Steps
title_sort machine learning for precision health economics and outcomes research p heor conceptual review of applications and next steps
url https://doi.org/10.36469/jheor.2020.12698
work_keys_str_mv AT yixichen machinelearningforprecisionhealtheconomicsandoutcomesresearchpheorconceptualreviewofapplicationsandnextsteps
AT viktorvchirikov machinelearningforprecisionhealtheconomicsandoutcomesresearchpheorconceptualreviewofapplicationsandnextsteps
AT xiaoconglmarston machinelearningforprecisionhealtheconomicsandoutcomesresearchpheorconceptualreviewofapplicationsandnextsteps
AT jingangyang machinelearningforprecisionhealtheconomicsandoutcomesresearchpheorconceptualreviewofapplicationsandnextsteps
AT haiboqiu machinelearningforprecisionhealtheconomicsandoutcomesresearchpheorconceptualreviewofapplicationsandnextsteps
AT jianfengxie machinelearningforprecisionhealtheconomicsandoutcomesresearchpheorconceptualreviewofapplicationsandnextsteps
AT ningsun machinelearningforprecisionhealtheconomicsandoutcomesresearchpheorconceptualreviewofapplicationsandnextsteps
AT chengminggu machinelearningforprecisionhealtheconomicsandoutcomesresearchpheorconceptualreviewofapplicationsandnextsteps
AT pengdong machinelearningforprecisionhealtheconomicsandoutcomesresearchpheorconceptualreviewofapplicationsandnextsteps
AT xingao machinelearningforprecisionhealtheconomicsandoutcomesresearchpheorconceptualreviewofapplicationsandnextsteps