Sangre Por Salud (SPS) Biobank: cohort profile
Purpose The Sangre Por Salud (SPS) Biobank was established to facilitate biomedical research opportunities for the Latino community by creating an easily accessible prospective cohort for scientists interested in studying health conditions and health disparities in this population.Participants Indiv...
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| Format: | Article |
| Language: | English |
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BMJ Publishing Group
2025-02-01
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| Series: | BMJ Open |
| Online Access: | https://bmjopen.bmj.com/content/15/2/e093445.full |
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| author | Richard R Sharp Euijung Ryu Janet E Olson Karen Meagher James R Cerhan Davinder Singh Suzette Bielinski Emmil Zarrugh Marlene E Girardo Giovanna Moreno Garzon Valentina Hernandez Sharon Levey Crystal Gonzalez Daniela B Pompa Gabriel Q Shaibi Lawrence Mandarino Steven Thibodeau Elena De Filippis |
| author_facet | Richard R Sharp Euijung Ryu Janet E Olson Karen Meagher James R Cerhan Davinder Singh Suzette Bielinski Emmil Zarrugh Marlene E Girardo Giovanna Moreno Garzon Valentina Hernandez Sharon Levey Crystal Gonzalez Daniela B Pompa Gabriel Q Shaibi Lawrence Mandarino Steven Thibodeau Elena De Filippis |
| author_sort | Richard R Sharp |
| collection | DOAJ |
| description | Purpose The Sangre Por Salud (SPS) Biobank was established to facilitate biomedical research opportunities for the Latino community by creating an easily accessible prospective cohort for scientists interested in studying health conditions and health disparities in this population.Participants Individuals self-identifying as Latino, aged 18–85 years, were prospectively recruited from the primary care Internal Medicine clinic at Mountain Park Health Center in Phoenix, Arizona. After obtaining informed consent, detailed medical history questionnaires were captured, and blood samples were obtained for common laboratory tests. Participants authorised the research team to access their electronic health records for research purposes. In addition, participants had serum, plasma and DNA samples isolated and stored at the Mayo Clinic Arizona Biorepository Laboratory for long-term storage and future access. As part of the study, participants consented and agreed to be contacted for potential participation in future research studies.Findings to date 3756 participants provided informed consent, of whom 3733 completed all study questionnaires, an oral glucose tolerance test and had blood collected and stored. The SPS cohort is predominantly composed of females (72%), with a median age at time of consent of 42 years. All participants self-identified as Hispanic/Latino, 45% were married, 53% were employed for wages and 60% had less than a high school degree. Around 25% of participants met diagnostic criteria for overweight (BMI 25–29 kg/m2), and 49% met for obesity (BMI≥30 kg/m2). At time of recruitment, hypertension, hyperlipidaemia and depression affected 22%, 20% and 13% of the cohort, respectively.Future plans We plan to regularly update the participants’ electronic health records and self-reported health data to longitudinal research. Additionally, we plan to obtain a more comprehensive genomic analysis on the entire cohort, ensuring greater research interest and investigation into the underlying genetic factors that contribute to disease susceptibility in this cohort. |
| format | Article |
| id | doaj-art-507bdabcc8854c4bbee0db4f20718c03 |
| institution | Kabale University |
| issn | 2044-6055 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | BMJ Publishing Group |
| record_format | Article |
| series | BMJ Open |
| spelling | doaj-art-507bdabcc8854c4bbee0db4f20718c032025-02-11T20:20:10ZengBMJ Publishing GroupBMJ Open2044-60552025-02-0115210.1136/bmjopen-2024-093445Sangre Por Salud (SPS) Biobank: cohort profileRichard R Sharp0Euijung Ryu1Janet E Olson2Karen Meagher3James R Cerhan4Davinder Singh5Suzette Bielinski6Emmil Zarrugh7Marlene E Girardo8Giovanna Moreno Garzon9Valentina Hernandez10Sharon Levey11Crystal Gonzalez12Daniela B Pompa13Gabriel Q Shaibi14Lawrence Mandarino15Steven Thibodeau16Elena De Filippis175 Biomedical Ethics Research Program, Mayo Clinic, Rochester, Minnesota, USAComputational Biology, Mayo Clinic, Rochester, Minnesota, USADepartment of Quantitative Health Sciences, Mayo Clinic, Rochester, Minnesota, USABiomedical Ethics Research Program, Mayo Clinic, Rochester, Minnesota, USA2 Department of Quantitative Health Sciences, Mayo Clinic, Rochester, New York, USALeeds Children’s HospitalDivision of Epidemiology, Mayo Clinic, Rochester, Minnesota, USA1 Center for Individualized Medicine, Mayo Clinic Arizona, Scottsdale, Arizona, USA2 Department of Quantitative Health Sciences, Mayo Clinic, Rochester, New York, USA1 Center for Individualized Medicine, Mayo Clinic Arizona, Scottsdale, Arizona, USA4 Mountain Park Health Center, Phoenix, Arizona, USA1 Center for Individualized Medicine, Mayo Clinic Arizona, Scottsdale, Arizona, USA4 Mountain Park Health Center, Phoenix, Arizona, USA1 Center for Individualized Medicine, Mayo Clinic Arizona, Scottsdale, Arizona, USA6 College of Health Solutions, Arizona State University, Phoenix, Arizona, USA7 Division of Endocrinology, Diabetes and Metabolism, University of Arizona Medical Center, Tucson, Arizona, USA8 Division of Laboratory Genetics, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA9 Division of Endocrinology, Diabetes and Metabolism, Mayo Clinic Arizona, Scottsdale, Arizona, USAPurpose The Sangre Por Salud (SPS) Biobank was established to facilitate biomedical research opportunities for the Latino community by creating an easily accessible prospective cohort for scientists interested in studying health conditions and health disparities in this population.Participants Individuals self-identifying as Latino, aged 18–85 years, were prospectively recruited from the primary care Internal Medicine clinic at Mountain Park Health Center in Phoenix, Arizona. After obtaining informed consent, detailed medical history questionnaires were captured, and blood samples were obtained for common laboratory tests. Participants authorised the research team to access their electronic health records for research purposes. In addition, participants had serum, plasma and DNA samples isolated and stored at the Mayo Clinic Arizona Biorepository Laboratory for long-term storage and future access. As part of the study, participants consented and agreed to be contacted for potential participation in future research studies.Findings to date 3756 participants provided informed consent, of whom 3733 completed all study questionnaires, an oral glucose tolerance test and had blood collected and stored. The SPS cohort is predominantly composed of females (72%), with a median age at time of consent of 42 years. All participants self-identified as Hispanic/Latino, 45% were married, 53% were employed for wages and 60% had less than a high school degree. Around 25% of participants met diagnostic criteria for overweight (BMI 25–29 kg/m2), and 49% met for obesity (BMI≥30 kg/m2). At time of recruitment, hypertension, hyperlipidaemia and depression affected 22%, 20% and 13% of the cohort, respectively.Future plans We plan to regularly update the participants’ electronic health records and self-reported health data to longitudinal research. Additionally, we plan to obtain a more comprehensive genomic analysis on the entire cohort, ensuring greater research interest and investigation into the underlying genetic factors that contribute to disease susceptibility in this cohort.https://bmjopen.bmj.com/content/15/2/e093445.full |
| spellingShingle | Richard R Sharp Euijung Ryu Janet E Olson Karen Meagher James R Cerhan Davinder Singh Suzette Bielinski Emmil Zarrugh Marlene E Girardo Giovanna Moreno Garzon Valentina Hernandez Sharon Levey Crystal Gonzalez Daniela B Pompa Gabriel Q Shaibi Lawrence Mandarino Steven Thibodeau Elena De Filippis Sangre Por Salud (SPS) Biobank: cohort profile BMJ Open |
| title | Sangre Por Salud (SPS) Biobank: cohort profile |
| title_full | Sangre Por Salud (SPS) Biobank: cohort profile |
| title_fullStr | Sangre Por Salud (SPS) Biobank: cohort profile |
| title_full_unstemmed | Sangre Por Salud (SPS) Biobank: cohort profile |
| title_short | Sangre Por Salud (SPS) Biobank: cohort profile |
| title_sort | sangre por salud sps biobank cohort profile |
| url | https://bmjopen.bmj.com/content/15/2/e093445.full |
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